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Heart infection registry aims to unlock better treatments

NCT ID NCT06434012

Knowledge-focused Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This registry collects detailed information from 1,000 patients with infective endocarditis, a serious heart infection. Researchers will track demographics, microbiology, imaging, and outcomes to understand current treatment effectiveness and guide future studies. The goal is to improve diagnosis and management of this life-threatening condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this registry could help identify better ways to diagnose and treat infective endocarditis, potentially reducing deaths and complications.
What could go wrong
This is an observational registry, not a treatment trial. It collects data but does not test any new therapy, so direct patient benefits may take years to emerge.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2019

Expected to finish

Apr 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

There are approximately 150 cases of endocarditis each year treated within the trust and recruitment is expected to be rapid

Ages

16 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Patients aged 16 and over (Patients under 16 years of age are not admitted to Barts Heart Centre) * Patients admitted to Barts Heart Centre with confirmed Endocarditis (see above) * Patients attending outpatients with confirmed/suspected Endocarditis * Patients with possible IE who complete treatment for endocarditis * Patients with cardiac device related Endocarditis * Patients with the ability to provide informed consent Exclusion Criteria: * • Patients with pacemaker pocket infection with no evidence of pacemaker lead or valve infection * Patients who refuse consent to be included in the research database * Patients with "rejected" endocarditis

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Conditions

The condition(s) this trial relates to.

bacterial endocarditis endocarditis infective endocarditis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endocarditis Endocarditis, bacterial Infective endocarditis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • St Bartholomews Hospital

    RECRUITING

    London, United Kingdom

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