INFECTIVE ENDOCARDITIS

This study compares two antibiotic approaches for a serious heart valve infection caused by staph bacteria. One group gets a standard treatment that includes the drug rifampin, while the other group gets a treatment without it. The goal is to see if skipping rifampin is just as e…

This study tests whether adding a special virus mixture (phage therapy) to standard antibiotics can improve outcomes for people with a serious heart valve infection called infective endocarditis. About 30 participants will receive either the phage therapy or a placebo alongside t…

This study tests whether replacing an infected heart device immediately after removal is as safe and effective as waiting for a later procedure. About 176 adults with device infections will be randomly assigned to either immediate or delayed reimplantation. The main goal is to se…

This study compares 3D cone beam CT scans to standard dental X-rays in 170 patients hospitalized for infective endocarditis, a serious heart infection. The goal is to see if the 3D scan detects more hidden mouth infections that could cause the heart infection to return. Participa…

This study is testing whether a special PET/CT scan using gallium-68 citrate can more accurately diagnose infections in artificial heart valves. Researchers will compare the scan results with the standard diagnosis after 3 months. The study involves 40 adults with suspected valve…

This study is creating a large registry and biobank of 10,000 adults with various infections, such as bloodstream, heart, and bone infections. Researchers will collect medical data and biological samples to describe the infections and their treatments. The goal is to better under…

This study looks at how people recover after infective endocarditis, a serious heart infection. Researchers want to see if a 12-week exercise program can improve physical fitness, fatigue, and quality of life. About 50 adults who had the infection will take surveys, do interviews…

This study is collecting data from 150 patients with a serious heart infection called endocarditis. Researchers will measure antibiotic levels in the blood and use that information to build a computer model. The goal is to find the best dose for each patient, which could help mor…

This study looks at whether people with a staph bloodstream infection and a low risk score (VIRSTA score less than 3) can safely avoid a routine heart ultrasound. About 700 participants will be randomly assigned to either get the ultrasound or not. The goal is to see if skipping …

This study follows 700 patients with infective endocarditis, a serious heart infection, to gather real-world data on complications and outcomes. Researchers aim to improve treatment guidelines, which currently rely on expert opinion due to limited evidence. No new drug or treatme…

This study is creating a large national database of infective endocarditis, a serious heart infection. Researchers will collect information from 5,000 patients across France to understand the disease's causes, risk factors, and how it is currently treated. The goal is to improve …