Heart device infection? new study tests immediate replacement

NCT ID NCT06250985

Recruiting now Disease control Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether replacing an infected heart device immediately after removal is as safe and effective as waiting for a later procedure. About 176 adults with device infections will be randomly assigned to either immediate or delayed reimplantation. The main goal is to see if immediate replacement leads to fewer serious events like death, blood infections, or new device infections within six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: timing of reimplantation (immediate vs. standard delayed)
What this could lead to: If successful, this could allow patients with infected heart devices to get a new device sooner, reducing hospital stays and risks from waiting.
What could go wrong: This is a phase 3 trial with 176 participants, so results are not yet proven. Immediate reimplantation may increase the risk of reinfection or other complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bacterial endocarditis endocarditis infective endocarditis prosthesis-related infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOCARDITIS, BACTERIAL

Contacts and locations

Locations

Rigshospitalet
RECRUITING

Copenhagen, 2100, Denmark

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