Heart device infection? new study tests immediate replacement

NCT ID NCT06250985

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether replacing an infected heart device immediately after removal is as safe and effective as waiting for a later procedure. About 176 adults with device infections will be randomly assigned to either immediate or delayed reimplantation. The main goal is to see if immediate replacement leads to fewer serious events like death, blood infections, or new device infections within six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

timing of reimplantation (immediate vs. standard delayed)

What this could lead to

If successful, this could allow patients with infected heart devices to get a new device sooner, reducing hospital stays and risks from waiting.

What could go wrong

This is a phase 3 trial with 176 participants, so results are not yet proven. Immediate reimplantation may increase the risk of reinfection or other complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacterial endocarditis endocarditis infective endocarditis prosthesis-related infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••