22,000 patients studied to unlock secrets of deadly heart infection

NCT ID NCT07671118

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This observational study looks back at 22,000 adults in Sweden diagnosed with infective endocarditis, a serious heart valve infection, since 1997. By linking national health records, researchers aim to understand which patients benefit most from valve surgery and what factors affect long-term survival. No new treatments are tested; instead, the goal is to learn from real-world data to guide future care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better decide when and how to perform valve surgery for infective endocarditis, potentially improving survival and reducing complications.

What could go wrong

This is an observational study, so it cannot prove cause and effect. Results may be influenced by factors not fully captured in the registry data.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacterial endocarditis endocarditis infective endocarditis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Karolinska Institutet

    Stockholm, Sweden