New diagnostic tool could speed up treatment for deadly heart infection

NCT ID NCT07682389

Recruiting now Diagnosis Sponsor: I.M. Sechenov First Moscow State Medical University Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study tests whether adding advanced molecular tests (like PCR and DNA sequencing) to standard blood cultures helps doctors identify the cause of infective endocarditis—a serious heart valve infection—more quickly. The goal is to see if this leads to more patients receiving the right antibiotics within 14 days. The trial involves 128 adults with suspected or confirmed infective endocarditis, comparing the new diagnostic algorithm to standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Molecular tests (PCR, sequencing)
What this could lead to: If successful, this diagnostic algorithm could help doctors prescribe targeted antibiotics sooner for infective endocarditis, potentially reducing complications.
What could go wrong: This is a relatively small trial (128 participants) testing a diagnostic approach, not a treatment itself. The algorithm may not improve outcomes or may be difficult to implement in routine care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INFECTIVE ENDOCARDITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

endocarditis infective endocarditis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFECTIVE ENDOCARDITIS MICROBIOLOGY

Contacts and locations

Locations

A.N. Bakulev National Medical Research Center for Cardiovascular Surgery of the Russian Ministry of Health
NOT_YET_RECRUITING

Moscow, Russia
City Clinical Hospital Named After S. S. Yudin
RECRUITING

Moscow, Russia
City Clinical Hospital №67 Named After L. A. Vorokhobova
RECRUITING

Moscow, Russia

More trials for these conditions

Other studies related to the condition(s) this trial covers.