New diagnostic tool could speed up treatment for deadly heart infection
NCT ID NCT07682389
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests whether adding advanced molecular tests (like PCR and DNA sequencing) to standard blood cultures helps doctors identify the cause of infective endocarditis—a serious heart valve infection—more quickly. The goal is to see if this leads to more patients receiving the right antibiotics within 14 days. The trial involves 128 adults with suspected or confirmed infective endocarditis, comparing the new diagnostic algorithm to standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Molecular tests (PCR, sequencing)
What this could lead to
If successful, this diagnostic algorithm could help doctors prescribe targeted antibiotics sooner for infective endocarditis, potentially reducing complications.
What could go wrong
This is a relatively small trial (128 participants) testing a diagnostic approach, not a treatment itself. The algorithm may not improve outcomes or may be difficult to implement in routine care.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for INFECTIVE ENDOCARDITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- OSCAR Study: Oritavancin for Heart Infections (NCT07550595)
- Infectious Disease Registry & Biobank Study | NCT06418048
- COUNT Study: Tracer Uptake in TAVR Valves (NCT03683355)
- Phage Therapy for Endocarditis Trial (NCT06870409)
- Heart Rehab After Endocarditis Study | NCT06704048
- Oral vs IV Antibiotics for Endocarditis (NCT02701595)
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
A.N. Bakulev National Medical Research Center for Cardiovascular Surgery of the Russian Ministry of Health
NOT_YET_RECRUITINGMoscow, Russia
Contact
-
City Clinical Hospital Named After S. S. Yudin
RECRUITINGMoscow, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
City Clinical Hospital №67 Named After L. A. Vorokhobova
RECRUITINGMoscow, Russia
Contact