Could many staph patients skip heart scans? major trial aims to find out

NCT ID NCT06457386

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether people with a staph bloodstream infection and a low risk score (VIRSTA score less than 3) can safely avoid a routine heart ultrasound. About 700 participants will be randomly assigned to either get the ultrasound or not. The goal is to see if skipping it leads to similar rates of death or infection relapse, potentially simplifying care for many patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that many patients with staph bloodstream infections can safely avoid routine heart ultrasound, simplifying care and reducing costs.
What could go wrong: This is a non-inferiority trial, so it may not prove that skipping echocardiography is better—only that it is not worse. The results may not apply to patients with higher risk scores.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis endocarditis infective endocarditis staphylococcal infection staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTEREMIA INFECTIVE ENDOCARDITIS STAPHYLOCOCCUS AUREUS

Contacts and locations

Locations

Bichat Claude Bernard Hospital
RECRUITING

Paris, 75018, France

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