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Could a 30-Day blood thinner regimen prevent clots after spine cancer surgery?

NCT ID NCT07713875

Not yet recruiting Disease control Sponsor: James Bayley Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

People who have spine surgery for cancer that has spread are at high risk for dangerous blood clots in the legs or lungs. Currently, blood-thinning medicine is stopped when patients leave the hospital. This trial tests whether taking apixaban (Eliquis) by mouth for 30 days after discharge can reduce that risk. About 50 adults will take the medicine and be followed by phone for three months, and their results will be compared to a similar group from the past who did not receive extended treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a blood-thinning medicine called apixaban (brand name Eliquis) taken as a 2.5 mg tablet twice daily for 30 days after hospital discharge
What this could lead to
If it works, this could establish a new standard of care to prevent life-threatening blood clots after spine surgery for cancer that has spread.
What could go wrong
This is a small, single-center study with only 50 participants, so results may not apply broadly. Bleeding is a known risk of blood thinners, and the trial will carefully monitor for it.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone disorder metastatic malignant neoplasm in the spinal cord pulmonary embolism Venous Thrombosis venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEEP VEIN THROMBOSIS (DVT) PULMONARY EMBOLISM (PE) SPINE METASTASIS VENOUS THROMBOEMBOLISM (VTE)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Mercy Hospital

    Pittsburgh, Pennsylvania, 15219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UPMC Presbyterian Hospital

    Pittburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UPMC Shadyside Hospital

    Pittburgh, Pennsylvania, 15232, United States

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