Could a quick, dye-free CT scan spot deadly lung clots?
NCT ID NCT07527117
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether a low-dose CT scan without contrast dye can accurately detect pulmonary embolism (blood clots in the lungs). Researchers will enroll 750 adults suspected of having a clot and add two very low-radiation CT scans to their standard dye-based scan. The goal is to see if the dye-free method can reliably rule out clots, potentially offering a safer option for patients who cannot receive contrast dye.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
low-dose non-contrast chest CT scan
What this could lead to
If successful, this could offer a safer, dye-free way to diagnose pulmonary embolism, especially for patients who cannot tolerate contrast dye.
What could go wrong
This is an early-stage diagnostic study, not a treatment trial. The new method may not be accurate enough to replace standard scans, and there is a small radiation risk from the extra CT images.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02420, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••