Post-COVID-19 disorder

This trial tests whether adding a 12-week digital maintenance program to standard inpatient rehabilitation helps people with post-COVID syndrome maintain improvements in quality of life and symptoms. Participants are randomly assigned to either rehabilitation alone or rehabilitat…

This study tests whether a combination of a special omega-3 supplement (LIPINOVA®) and a home-based exercise and education program can improve quality of life for people with lingering post-COVID symptoms. About 146 adults aged 18–70 who have had symptoms for more than 12 weeks w…

This study tested whether a combination of L-citrulline supplements, nutritional therapy, and pulmonary rehabilitation could help recovered COVID-19 patients improve their blood vessel health, body composition, and physical function. 43 adults aged 40-80 who had recovered from CO…

Many people who had COVID-19 continue to struggle with fatigue, memory problems, and difficulty managing daily tasks. This study follows 120 adults with these symptoms who join a 10-week group rehabilitation program at a Swedish hospital. The program brings together occupational …

This pilot study tested whether a non-invasive vagus nerve stimulator can help people with post-COVID syndrome who suffer from fatigue and headaches. Eighteen participants used the device, and researchers measured changes in their functional status and fatigue levels. The goal is…

This study looks at whether online psychotherapy, a physical activity program, or a combination of both can reduce fatigue in people with Post-COVID syndrome. 195 adults with fatigue will be assigned to one of three groups for 3 months of treatment. The goal is to find which appr…

This trial asks whether kinesiotaping or traditional physiotherapy better eases mid-back pain that lingers after a COVID-19 infection. Adults who have recovered from COVID-19 and now have mechanical mid-back pain will receive either elastic tape applied to the back for 10 days or…

This trial investigates whether ginkgo biloba, piracetam, or a combination of both can help people recover from persistent symptoms after COVID-19, such as memory problems and fatigue. The study enrolls adults aged 18 to 70 who had COVID-19 within the past three months. Participa…

This study tests whether two dietary supplements—eicosapentaenoic acid (EPA), an omega-3 fatty acid, and specialized pro-resolving lipid mediators (SPMs)—can reduce depressive symptoms in adults with long COVID. Participants take either EPA, SPMs, or a placebo daily for 12 weeks.…

This pilot study tested a Spanish-language chronic-disease self-management program called 'Tomando control de su salud' in 47 adults with Long-COVID and at least one other chronic condition in Puerto Rico. The goal was to see if the program could improve quality of life, reduce f…

This completed study looked at whether a once-a-week home-based resistance exercise program could help reduce fatigue in veterans aged 50 and older with Long COVID. The study enrolled 21 participants and measured changes in muscle strength and perceived tiredness. The goal was to…

This completed study tested a digital rehab program combining cognitive training, physical exercise, and mindfulness for people with long COVID who have memory and thinking problems. 172 adults with persistent cognitive symptoms at least 12 weeks after COVID-19 took part. The pro…

This study tested Pycnogenol, a natural pine bark extract, against a placebo in 153 adults with Long COVID. The goal was to see if it improves overall health and reduces symptoms like fatigue and brain fog. Participants took the supplement for 12 weeks and reported their health s…

This study tested two breathing devices—a Lung Boost trainer and an incentive spirometer—to see which better improves lung function in 60 children aged 4-9 with cerebral palsy who had recovered from COVID-19. All children also received standard breathing therapy. The goal was to …

This study tested whether a non-invasive treatment called enhanced external counterpulsation (EECP) can improve heart and lung function in adults with long COVID. Ten participants received EECP therapy on one of two schedules. Researchers measured exercise capacity, symptoms, and…

This small study tested whether sitting under a bright light for 30 minutes a day for two weeks could help people with long-lasting fatigue after COVID-19. Twelve adults who had been tired for months after their infection took part. The goal was to see if the light therapy could …

This study tested whether a remote cognitive strategy training program (CO-OP) is feasible for people with Post-COVID syndrome who have memory or thinking problems. 65 participants learned a step-by-step problem-solving method (Goal-Plan-Do-Check) to improve daily activities. The…

This study tested whether a 6-week personalized day-hospital program could improve quality of life for 80 people with persistent long COVID symptoms like fatigue, shortness of breath, and brain fog. The program included group education, tailored exercise, and cognitive behavioral…

This Canadian trial tested two drugs, ibudilast and pentoxifylline, against a placebo in 460 adults with lingering COVID-19 symptoms. Participants took the drugs for 2 months and were followed for 4 more months to see if symptoms improved. The goal is to find safe, effective trea…

This study looked at whether eating 2 ounces of walnuts every day for 12 weeks could improve memory and reduce brain fog in adults over 40 with Long-COVID. About 31 people took part, comparing walnut eaters to those getting usual care. The goal was to see if walnuts, which are ri…

This study looked at whether a breathing exercise using pressure biofeedback can help women with long COVID-19 improve their breathing muscle strength. 80 women who had COVID-19 and still had breathing problems took part. They did special diaphragm training for four weeks. The go…

This study tested a device called the Human Regenerator Jet, which emits cold atmospheric plasma, to see if it can improve quality of life in adults with chronic stress, fatigue, pain, or Long COVID. Forty participants received 10 sessions of either the plasma or plain air, and r…

This study tested whether amantadine, a medication used for other conditions, can improve memory and thinking problems in people with Long COVID. 64 adults with lasting cognitive issues after a COVID infection took part. Researchers also looked for lab markers that might predict …

This study tested a rehabilitation program to help adults with Post-COVID-19 syndrome who suffer from ongoing fatigue. 54 participants completed the program, which aimed to reduce tiredness and improve daily life. The study measured fatigue using several scales to see if the reha…

This study tested a 12-week smartphone program called SuperCAP for people with post-COVID syndrome. The program includes daily games, exercises, and videos to improve thinking, mood, and daily function. Sixty adults with ongoing cognitive complaints took part, and researchers mea…

This study tested a 10-week group program that teaches self-help strategies from European, Chinese, and Indian traditional medicine for people with post-COVID syndrome. 86 adults with persistent symptoms after COVID-19 took part. The goal was to see if these techniques, added to …

This study tested whether infusions of donor stem cells (HB-adMSCs) could reduce long COVID symptoms like extreme fatigue, brain fog, and headache. About 79 adults with chronic post-COVID syndrome received four IV doses of stem cells or a placebo over 10 weeks. Researchers tracke…

This study tested a program called AIR + Mindfulness, which aims to retrain parts of the brain (amygdala and insula) to reduce long COVID symptoms like fatigue, pain, and brain fog. 120 adults with persistent COVID took part in either the brain retraining program or a relaxation …

This study tested a blood filtering procedure called immunoadsorption to see if it reduces fatigue in people with post-COVID syndrome. 63 patients received either the real procedure or a sham version over 14 days. The goal was to measure changes in fatigue and other symptoms like…

This study tested whether motion-controlled video games in virtual reality could help people with long COVID feel better. 79 participants either played VR games or did standard exercises. Researchers measured pain, fatigue, mood, and quality of life to see if the VR approach was …

This study looks at long-term health problems in 400 adults who had COVID-19 and are now preparing for surgery. Researchers will ask about ongoing symptoms like breathing issues, heart problems, and fatigue. No new treatments are given; the goal is to understand how past COVID-19…

This study looks at why people with post-COVID syndrome have trouble exercising and feel very tired. Researchers will compare 62 post-COVID patients with healthy volunteers, monitoring their responses to different types of exercise like high-intensity intervals, moderate walking,…

This study looks at why some people have Long COVID symptoms like fatigue and brain fog. It also tests if a 12-week smartphone app with breathing exercises, relaxation, and energy management can help. About 120 adults with Long COVID are taking part to share health data and try t…

This completed study took blood samples from 62 people with Long COVID and compared them to healthy controls. Researchers looked for specific immune and metabolic patterns that might explain why symptoms persist. The goal is to better understand Long COVID, not to test a treatmen…

This study tested a program for people with long-COVID that includes an online screening, a detailed in-person assessment, and digital training modules with a personal counselor. 192 participants from Bavaria took part to see if this approach is practical and helpful. The goal wa…

This study interviewed 25 adults with long COVID to understand how the condition affects their daily life, work, and experience with healthcare. Researchers aimed to learn about the challenges patients face and what helps or hinders their return to work. The study does not test a…

This completed study looked at 355 adults with Long COVID in Suffolk and North Essex to understand their symptoms and rehabilitation needs up to 36 months after infection. The goal was to better diagnose and manage the condition, focusing on helping people return to everyday acti…

This study looked at 51 adults who had COVID-19 2 to 12 months earlier and still had brain fog or other thinking problems. Researchers checked if the virus was still hiding in the nose's smell center. They compared these patients to a control group to see if lingering virus is li…

This study followed over 4,200 Dutch COVID-19 patients for up to two years to learn about long COVID symptoms like exhaustion, breathing problems, and mental health issues. Researchers also looked at how these symptoms affect quality of life and what factors might predict who get…

This completed study used a special imaging method called electrical impedance tomography (EIT) to look at lung function in 100 people with long COVID who have trouble breathing, compared to 50 healthy volunteers. The goal was to see if EIT can detect changes in how air moves thr…