Can retraining your brain ease long COVID?
NCT ID NCT05956405
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a program called AIR + Mindfulness, which aims to retrain parts of the brain (amygdala and insula) to reduce long COVID symptoms like fatigue, pain, and brain fog. 120 adults with persistent COVID took part in either the brain retraining program or a relaxation program over two months. The goal was to see if this approach could improve their quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AIR + Mindfulness program (behavioral intervention)
What this could lead to
If it works, this could offer a non-drug way to ease long COVID symptoms like fatigue, brain fog, and mood issues.
What could go wrong
This is a small, completed trial without a placebo control, so results may not be widely applicable. The intervention is behavioral, not a cure, and benefits may vary.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Psychiatry. Miguel Servet University Hospital
Zaragoza, 50009, Spain