Osteoarthritis, hand

This study is testing a new modular shoulder replacement system in 105 people who need complex revision surgery due to joint disease, trauma, or cancer. The device can replace part or all of the upper arm bone. Researchers are tracking how long the implant lasts and how well pati…

This study followed 413 people with hip arthritis who received a new type of hip replacement called the OXINIUM DH system. The goal was to see how well the implant worked and how safe it was over 10 years. Researchers checked pain, movement, and whether the implant stayed in plac…

This study is checking the long-term safety and performance of two hip implant devices (RingLoc Bipolar Acetabular Cup and Endo II Femoral Head) used in hip replacement surgery. Researchers will follow 116 patients who had their surgery at least eight years ago, tracking complica…

This study tests whether a pharmacist-led program can help people reduce their risk of heart disease. Over 1,000 adults with conditions like diabetes, high blood pressure, or obesity are taking part. Pharmacists use a step-by-step guide to assess risk and support lifestyle change…

This study tests whether methotrexate, a drug used for other types of arthritis, can reduce pain and improve hand function in people with a severe form of hand osteoarthritis. About 163 adults with moderate to severe finger pain will receive either methotrexate or a placebo for 6…

This study follows 163 people who received a LEGION knee replacement with a special VERILAST bearing surface to treat degenerative joint disease. Researchers track how long the implant lasts and how well patients function over time. The goal is to see if this newer device perform…

This study follows 200 people who receive a cementless knee replacement (GMK Sphere) to see how long the implant lasts and how well it works. Participants have severe knee damage from arthritis or other conditions. The goal is to monitor safety and performance in real-world use, …

This study is testing a device called KeriFuse® that is implanted into the finger joint to fuse the bones together. It is for people with arthritis in the last joint of the finger or thumb. The goal is to see if it reduces pain and successfully fuses the joint within three months…

This study is testing a new thumb joint replacement called the Touch® prosthesis in 216 adults with severe thumb osteoarthritis. The implant is designed to reduce pain and improve thumb mobility. Researchers will check how well it works and how safe it is over time, starting at 3…

This early study tests an injection called Allocetra for osteoarthritis at the base of the thumb. The trial includes 46 adults aged 40 and older whose pain hasn't improved with standard treatments. Researchers are checking if the injection is safe and whether it can reduce pain a…

This study tests whether using a lower-pressure tourniquet during orthopedic surgeries can reduce pain and the need for opioid painkillers afterward. Standard tourniquets use high pressure, which can cause muscle weakness and pain. The experimental device sets pressure based on t…

This study looks at whether a 6-day course of oral steroids after orthopedic surgery can help reduce pain, nausea, and improve movement. About 500 adults having common surgeries like joint replacement or fracture repair will be randomly assigned to receive either standard care or…

This early-stage trial is testing whether injecting donated fat tissue into the small joints of the hand can reduce pain and improve movement in people with hand osteoarthritis. About 34 adults with joint pain and X-ray evidence of arthritis will receive the injection under local…

This study tests whether turmeric (curcumin) can reduce pain and improve function in people with thumb-joint arthritis. One hundred adults will take turmeric capsules for four weeks and a placebo for another four weeks, then compare results. The goal is to see if this common spic…

This study tests whether injecting botulinum toxin into the thumb joint can reduce pain and improve function in people with thumb osteoarthritis (rhizarthrosis). Sixty adults with moderate to severe pain who have not responded to standard painkillers will receive either botulinum…

This study tests whether adding high-intensity laser therapy to a standard exercise program can better reduce pain and improve function in people with thumb osteoarthritis. 48 participants with stage I-III thumb joint arthritis will receive laser treatment three times a week for …

This study follows up to 500 people with acute or chronic inflammatory disorders, such as infections or immune problems, over time. Researchers will monitor participants with standard tests and may screen them for other studies. The goal is to better understand these conditions a…

This study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…

This study follows over 1,500 people who received an Attune total knee replacement to see how long the implant lasts—up to 15 years. Participants had non-inflammatory degenerative joint disease (like osteoarthritis). The goal is to gather real-world data on the durability of four…

This study collects blood, urine, and tissue samples from 330 adults with advanced lung or head and neck cancer to improve precision medicine. Researchers will analyze genetic changes in these samples and grow some tumors in mice to compare DNA. The goal is to refine liquid biops…

This study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…

This study uses artificial intelligence to analyze X-rays and CT scans of the thumb joint affected by osteoarthritis. Researchers aim to develop automated tools to classify disease severity, detect implant loosening, and create 3D models for better surgical planning. The study in…

This study tests whether giving patients with hand problems like carpal tunnel syndrome or trigger finger a decision aid—a booklet with clear information about their condition and treatment options—helps them feel more satisfied and less conflicted about their choices. About 126 …

This study is tracking 120 people who received a HYPE SCS hip stem during total hip replacement. Researchers will monitor how long the implant lasts, how satisfied patients are, and any complications over 5 years. The goal is to confirm the device is safe and works as intended in…

This study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …

This study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…

This study looks at whether helping people with inflammatory arthritis address social needs—like food, housing, or transportation—can reduce missed doctor visits. About 100 adults with conditions like rheumatoid arthritis or lupus who have missed appointments in the past year wil…

This study was designed to see if a pre-surgery meeting with an occupational therapist helps people with hand injuries or thumb arthritis recover faster and attend their therapy appointments. It planned to include adults needing surgery for a broken wrist, a cut tendon, or thumb …