New knee implant tested for Long-Term success

NCT ID NCT02380092

Ongoing Disease control Sponsor: Smith & Nephew, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study follows 163 people who received a LEGION knee replacement with a special VERILAST bearing surface to treat degenerative joint disease. Researchers track how long the implant lasts and how well patients function over time. The goal is to see if this newer device performs as well as or better than an older model.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LEGION Primary Total Knee System with VERILAST bearing surface (a knee replacement device)
What this could lead to: If successful, this could confirm that the LEGION knee system is a safe and durable option for people needing knee replacement due to arthritis.
What could go wrong: This is a post-market study, not a new treatment. Results may not show major improvement over existing options, and some patients may still need revision surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

arthropathy osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENERATIVE JOINT DISEASE

Contacts and locations

Locations

AMEOS Klinikum Seepark Geestland

Langen, Kreis Geestland, 27607, Germany
CaritasKlinikum St. Joseph Saarbrücken-Dudweiler

Saarbrücken-Dudweiler, 66125, Germany
Evangelisches Krankenhaus Wien

Vienna, 1180, Austria
KniePraxis Prof. Dr. Tibesku

Straubing, 94315, Germany
OrthoCentrum

Hamburg, 20149, Germany
Orthopadische Krankenhaus Gersthof

Vienna, 1180, Austria
Servicio de C.O.T. Hospital Clínico Universitario de Santiago de Compostela

Santiago de Compostela, 15706, Spain

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