Botox for thumb arthritis? new trial tests pain relief
NCT ID NCT04829565
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injecting botulinum toxin into the thumb joint can reduce pain and improve function in people with thumb osteoarthritis (rhizarthrosis). Sixty adults with moderate to severe pain who have not responded to standard painkillers will receive either botulinum toxin or a placebo injection. The main goal is to measure pain changes after 3 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
botulinum toxin
What this could lead to
If it works, this could offer a new, non-surgical option to ease thumb arthritis pain and improve hand function.
What could go wrong
This is a small, early-phase trial with only 60 participants. The effect may be short-lived, and there is a risk of side effects like injection-site pain or muscle weakness.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU de Nice
Nice, PACA, 06000, France