New MRI technique aims to sharpen arthritis bone erosion detection

NCT ID NCT06383585

Ongoing Diagnosis Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This Mayo Clinic study tests a new 3D MRI sequence called oZTEo, enhanced with deep learning, to detect bone erosions in the hands of people with inflammatory arthritis. The goal is to see if this advanced scan finds erosions better than standard MRI or X-rays. The study will enroll 25 adults who already have hand X-rays showing bone damage and are scheduled for a routine hand MRI.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 3D DL oZTEo MRI pulse sequence (imaging device)
What this could lead to: If successful, this could improve how doctors spot bone damage in arthritis patients, leading to earlier treatment decisions.
What could go wrong: This is a very small, early study (25 people) testing a new imaging method. It may not show clear benefits over standard MRI, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

arthritic joint disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLAMMATORY ARTHRITIS

Contacts and locations

Locations

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

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