Can a Blood-Derived injection ease thumb arthritis pain?

NCT ID NCT06193499

Ongoing Disease control Sponsor: Karolinska Institutet Source: ClinicalTrials.gov ↗

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial tests whether injecting platelet-rich plasma (PRP) into the thumb joint can reduce pain and improve function in people with thumb base osteoarthritis. Participants are randomly assigned to receive either PRP or a saline placebo injection, and neither they nor the researchers know which they get. The study measures pain during thumb use and hand disability over time to see if PRP offers meaningful relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Platelet-rich plasma (PRP) injected into the thumb joint
What this could lead to: If effective, PRP injections could offer a non-surgical option to reduce pain and improve hand function in people with thumb base osteoarthritis.
What could go wrong: This is a small, early-stage trial, and PRP's benefit over placebo is unproven. Results may not apply to all patients, and injection-related risks like pain or infection exist.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, hand

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS THUMB

Contacts and locations

Locations

Department of Hand Surgery Södersjukhuset

Stockholm, S-11883, Sweden

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