Thumb arthritis study tests PRP vs steroids – but ends early

NCT ID NCT03196310

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at three treatments for thumb base arthritis: a platelet-rich plasma (PRP) injection, a corticosteroid (Kenalog) injection, or a placebo (saline) injection. The goal was to see which best improved hand function and pain. The trial enrolled 74 people with early-stage thumb arthritis but was terminated early, so results are incomplete.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Platelet-rich plasma (PRP) and corticosteroid (Kenalog)

What this could lead to

If PRP proves effective, it could offer a longer-lasting, natural option for easing thumb arthritis pain without steroids.

What could go wrong

The trial was terminated early, so results are limited. PRP is still experimental for this use, and benefits may not be better than placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, hand

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Orthopedic Associates of Southwest Ohio

    Centerville, Ohio, 45459, United States