Intestinal disorder
MONDO:0005020A non-neoplastic or neoplastic disorder that affects the small or large intestine.
Also known as: disease of intestine, disease or disorder of intestine, disorder of intestine, intestinal disease, intestinal disorder, intestine disease, intestine disease or disorder, disease, intestinal
5443 clinical trials for this condition and its sub-types, 70 tagged with Intestinal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Intestinal disorder
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Large intestine disorder 2 trials · 3,821 incl. sub-types
11 sub-types
- Colorectal neoplasm 1,495 trials · 2,900 incl. sub-types Sub-types →
- Colonic disorder 18 trials · 1,470 incl. sub-types Sub-types →
- Rectal disorder 22 trials · 793 incl. sub-types Sub-types →
- Disorder of appendix 1 trial · 132 incl. sub-types Sub-types →
- Polyp of large intestine 60 trials · 114 incl. sub-types Sub-types →
- Anal canal cancer 22 trials · 44 incl. sub-types Sub-types →
- Epithelial tumor of anal canal 0 trials · 34 incl. sub-types Sub-types →
- Shigellosis 14 trials
- Crohn's colitis 7 trials
- Benign neoplasm of large intestine 4 trials · 6 incl. sub-types Sub-types →
- Colorectal Kaposi sarcoma 0 trials Sub-types →
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Intestinal neoplasm 4 trials · 3,080 incl. sub-types
6 sub-types
- Colorectal neoplasm 1,495 trials · 2,900 incl. sub-types Sub-types →
- Intestinal cancer 25 trials · 2,791 incl. sub-types Sub-types →
- Small intestine neoplasm 1 trial · 223 incl. sub-types Sub-types →
- Epithelial tumor of anal canal 0 trials · 34 incl. sub-types Sub-types →
- Intestinal neuroendocrine neoplasm 7 trials · 21 incl. sub-types Sub-types →
- Intestinal benign neoplasm 1 trial · 7 incl. sub-types Sub-types →
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Inflammatory bowel disease 430 trials · 1,081 incl. sub-types
40 sub-types
- Colitis 41 trials · 679 incl. sub-types Sub-types →
- Crohn disease 563 trials · 569 incl. sub-types Sub-types →
- Proctitis 2 trials · 21 incl. sub-types Sub-types →
- Inflammatory bowel disease 1 3 trials
- Undetermined colitis 3 trials
- Ulcerative proctosigmoiditis 2 trials
- ALPI-related inflammatory bowel disease 0 trials
- IL10-related early-onset inflammatory bowel disease 0 trials Sub-types →
- TRIM22-related inflammatory bowel disease 0 trials
- Cap polyposis 0 trials
- Cutaneous photosensitivity-lethal colitis syndrome 0 trials
- Inflammatory bowel disease (infantile ulcerative colitis) 31, autosomal recessive 0 trials
- Inflammatory bowel disease 10 0 trials
- Inflammatory bowel disease 11 0 trials
- Inflammatory bowel disease 12 0 trials
- Inflammatory bowel disease 13 0 trials
- Inflammatory bowel disease 14 0 trials
- Inflammatory bowel disease 15 0 trials
- Inflammatory bowel disease 16 0 trials
- Inflammatory bowel disease 17 0 trials
- Inflammatory bowel disease 18 0 trials
- Inflammatory bowel disease 19 0 trials
- Inflammatory bowel disease 2 0 trials
- Inflammatory bowel disease 20 0 trials
- Inflammatory bowel disease 21 0 trials
- Inflammatory bowel disease 22 0 trials
- Inflammatory bowel disease 23 0 trials
- Inflammatory bowel disease 24 0 trials
- Inflammatory bowel disease 26 0 trials
- Inflammatory bowel disease 27 0 trials
- Inflammatory bowel disease 29 0 trials
- Inflammatory bowel disease 3 0 trials
- Inflammatory bowel disease 30 0 trials
- Inflammatory bowel disease 4 0 trials
- Inflammatory bowel disease 5 0 trials
- Inflammatory bowel disease 6 0 trials
- Inflammatory bowel disease 7 0 trials
- Inflammatory bowel disease 8 0 trials
- Inflammatory bowel disease 9 0 trials
- Neonatal inflammatory skin and bowel disease 0 trials Sub-types →
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Gastroenteritis 20 trials · 839 incl. sub-types
9 sub-types
- Colitis 41 trials · 679 incl. sub-types Sub-types →
- Appendicitis 76 trials
- Intestinal infectious disease 3 trials · 49 incl. sub-types Sub-types →
- Inflammatory diarrhea 0 trials · 33 incl. sub-types Sub-types →
- Enteritis 5 trials · 23 incl. sub-types Sub-types →
- Eosinophilic gastroenteritis 6 trials · 7 incl. sub-types Sub-types →
- Campylobacteriosis 3 trials Sub-types →
- Intestinal tuberculosis 2 trials
- Salmonella gastroenteritis 0 trials
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Small intestine disorder 7 trials · 387 incl. sub-types
10 sub-types
- Small intestine neoplasm 1 trial · 223 incl. sub-types Sub-types →
- Duodenal disorder 1 trial · 109 incl. sub-types Sub-types →
- Celiac disease 81 trials Sub-types →
- Enteritis 5 trials · 23 incl. sub-types Sub-types →
- Pouchitis 18 trials
- Small intestinal bacterial overgrowth 18 trials
- Atresia of small intestine 0 trials
- Congenital short bowel syndrome 0 trials Sub-types →
- Small intestine diverticulitis 0 trials Sub-types →
- Small intestine duplication 0 trials Sub-types →
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Irritable bowel syndrome 223 trials
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Bowel dysfunction 11 trials · 211 incl. sub-types
1 sub-type
- Constipation disorder 189 trials · 202 incl. sub-types Sub-types →
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Glucose-galactose malabsorption 2 trials · 151 incl. sub-types
1 sub-type
- Glucose intolerance 149 trials
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Malabsorption syndrome 13 trials · 120 incl. sub-types
9 sub-types
- Celiac disease 81 trials Sub-types →
- Autoimmune enteropathy 2 trials · 11 incl. sub-types Sub-types →
- Lactose intolerance 9 trials · 10 incl. sub-types Sub-types →
- Idiopathic malabsorption due to bile acid synthesis defects 4 trials
- Intestinal disaccharidase deficiency 0 trials · 2 incl. sub-types Sub-types →
- Blind loop syndrome 1 trial
- Tropical sprue 1 trial
- Hereditary folate malabsorption 0 trials
- Lysine malabsorption syndrome 0 trials
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Intestinal obstruction 44 trials · 91 incl. sub-types
6 sub-types
- Ileus 10 trials · 42 incl. sub-types Sub-types →
- Intestinal volvulus 4 trials
- Duodenal obstruction 2 trials · 3 incl. sub-types Sub-types →
- Encapsulating peritoneal sclerosis 2 trials
- Intussusception 2 trials
- Intestinal impaction 0 trials
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Eosinophilic gastrointestinal disease 9 trials · 73 incl. sub-types
3 sub-types
- Eosinophilic esophagitis 67 trials Sub-types →
- Eosinophilic gastroenteritis 6 trials · 7 incl. sub-types Sub-types →
- Proton-pump inhibitor-responsive esophageal eosinophilia 0 trials
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Intestinal fistula 6 trials · 63 incl. sub-types
1 sub-type
- Anal fistula 57 trials
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Necrotizing enterocolitis 51 trials
1 sub-type
- Perinatal necrotizing enterocolitis 9 trials
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Short bowel syndrome 39 trials
1 sub-type
- Secondary short bowel syndrome 0 trials
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Intestinal motility disease 10 trials · 39 incl. sub-types
15 sub-types
- Hirschsprung disease 29 trials
- Multisystemic smooth muscle dysfunction syndrome 2 trials Sub-types →
- Goldberg-Shprintzen syndrome 0 trials
- Haddad syndrome 0 trials
- Hirschsprung disease-ganglioneuroblastoma syndrome 0 trials
- Hirschsprung disease-hearing loss-polydactyly syndrome 0 trials
- Hirschsprung disease-nail hypoplasia-dysmorphism syndrome 0 trials
- Hirschsprung disease-type D brachydactyly syndrome 0 trials
- Waardenburg-Shah syndrome 0 trials Sub-types →
- Chronic intestinal pseudoobstruction 0 trials Sub-types →
- Congenital diarrhea 6 0 trials
- Familial visceral myopathy 0 trials Sub-types →
- Intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency 0 trials
- Megacystis-microcolon-intestinal hypoperistalsis syndrome 0 trials Sub-types →
- Oculogastrointestinal muscular dystrophy 0 trials
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Diverticulitis 28 trials · 34 incl. sub-types
2 sub-types
- Diverticulitis of colon 19 trials
- Small intestine diverticulitis 0 trials Sub-types →
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Chronic intestinal failure 24 trials
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Neurogenic bowel 22 trials
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Postgastrectomy syndrome 2 trials · 20 incl. sub-types
2 sub-types
- Dumping syndrome 19 trials
- Afferent loop syndrome 0 trials
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Hypertrophic pyloric stenosis 16 trials
2 sub-types
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Parasitic intestinal disorder 0 trials · 16 incl. sub-types
7 sub-types
- Intestinal helminthiasis 3 trials · 9 incl. sub-types Sub-types →
- Cryptosporidiosis 5 trials
- Giardiasis 2 trials
- Protozoal dysentery 0 trials · 1 incl. sub-types Sub-types →
- Blastocystis infectious disease 0 trials
- Balantidiasis 0 trials
- Dientamoebiasis 0 trials
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Ischemic bowel disorder 8 trials · 15 incl. sub-types
1 sub-type
- Acute intestinal ischemia 12 trials
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Endometriosis of intestine 9 trials
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Intestinal perforation 9 trials
2 sub-types
- Perinatal intestinal perforation 0 trials
- Spontaneous intestinal perforation 0 trials
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Intestinal polyp 8 trials
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Protein-losing enteropathy 7 trials
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Intestinal atresia 3 trials · 6 incl. sub-types
2 sub-types
- Duodenal atresia 2 trials
- Multiple intestinal atresia 0 trials · 1 incl. sub-types Sub-types →
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Refractory celiac disease 4 trials
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Volvulus of midgut 4 trials
1 sub-type
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Abetalipoproteinemia 2 trials
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Pneumatosis cystoides intestinalis 2 trials
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Angiodysplasia of intestine 1 trial
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Steatorrhea 1 trial
1 sub-type
- Pancreatic steatorrhea 0 trials
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4-hydroxyphenylacetic aciduria 0 trials
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NK-cell enteropathy 0 trials
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Satoyoshi syndrome 0 trials
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Whipple disease 0 trials
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Collagenous sprue 0 trials
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Intestinal dysmotility syndrome 0 trials
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Intestinal lymphangiectasia 0 trials
2 sub-types
- Primary intestinal lymphangiectasia 0 trials
- Secondary intestinal lymphangiectasia 0 trials
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Isolated mesenteric vein thrombosis 0 trials
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Malakoplakia 0 trials
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Mucocele of appendix 0 trials
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Primary desmosis coli 0 trials
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Solitary rectal ulcer syndrome 0 trials
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Trichohepatoenteric syndrome 0 trials
2 sub-types
- Trichohepatoenteric syndrome 1 0 trials
- Trichohepatoenteric syndrome 2 0 trials
Most studied deeper sub-types
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Could a Gut-Healing shot fix hidden malnutrition?
Disease control Not yet recruitingThis study tests a drug called teduglutide in 55 undernourished women aged 18-35 in Bangladesh who have a chronic gut condition called environmental enteric dysfunction (EED). EED causes inflammation and poor nutrient absorption, with no proven treatment. Participants receive dai…
Phase 2 • Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Can a sticky pad on the belly replace invasive colon tests for kids?
Diagnosis Not yet recruitingThis trial tests whether a new non-invasive device, called Body Surface Colonic Mapping, can accurately measure colon movement in children. The device uses a sticky pad with electrodes placed on the abdomen to detect electrical activity from the colon. Researchers will compare it…
Sponsor: Murdoch Childrens Research Institute • Aim: Diagnosis
Last updated Sep 04, 2026 00:00 UTC
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Horseback therapy: a new hope for children with cerebral palsy?
Symptom relief Not yet recruitingThis trial tests whether hippotherapy—therapy involving horseback riding—can improve physical function, bladder and bowel symptoms, and family quality of life in children with cerebral palsy. Thirty children aged 7-15 will receive weekly 30-minute hippotherapy sessions for 8 week…
Sponsor: Fenerbahce University • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Horseback therapy: a new hope for autism symptoms?
Symptom relief Not yet recruitingThis trial tests whether adding hippotherapy—therapeutic horseback riding—to a standard special education program can improve physical function, bladder and bowel symptoms, and social communication in children with autism spectrum disorder. Thirty children will receive either the…
Sponsor: Fenerbahce University • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Could colonoscopy prep become a pill instead of a gallon of liquid?
Symptom relief Not yet recruitingThis study tests whether the powder used to clean the bowel before a colonoscopy can be taken as vegan capsules instead of mixing it into a liquid drink. Adults aged 18 to 75 who have had a prior colonoscopy will swallow many capsules with clear fluids. Researchers will check if …
Early phase 1 • Sponsor: Ottawa Hospital Research Institute • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Pickles and yogurt might ease bowel troubles in spinal cord injury
Symptom relief Not yet recruitingThis study tests whether eating at least 6 servings of fermented foods daily for 10 weeks can improve bowel function and gut health in adults with chronic spinal cord injury. Participants will be randomly assigned to either a high-fermented-food diet or a control diet. The resear…
Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Screening for celiac disease: could early diagnosis improve lives?
Knowledge-focused Not yet recruitingThis study follows 250 adults in Finland who were previously screened for celiac disease to see how early diagnosis affects their long-term health, diet habits, and quality of life. Researchers will track symptoms, gluten-free diet adherence, and overall well-being. The goal is t…
Sponsor: Tampere University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Should ICU tube feed be watered down? new study aims to find out
Knowledge-focused Not yet recruitingThis study will compare diluted and undiluted tube feeding in 80 critically ill adults after major abdominal surgery. Half will get extra fluids mixed with their feed, the other half will get undiluted feed with fluids given separately through an IV. The goal is to see which appr…
Sponsor: John Paul II Catholic University of Lublin • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC