Disorder of pilosebaceous unit

This study compares two topical medications—clascoterone cream and adapalene gel—for treating mild acne vulgaris. Researchers will enroll 60 people aged 12 to 35 with mild acne and randomly assign them to use one of the treatments for 12 weeks. The goal is to see which treatment …

This Phase 2 trial tests a cream called delgocitinib in 30 adults with frontal fibrosing alopecia, a condition that causes hair loss at the front of the scalp. Everyone in the study will use the cream for 24 weeks. Researchers will measure changes in hairline and hair counts to s…

This study tests whether a low daily dose of the acne drug isotretinoin can clear moderate to severe acne as effectively as the standard dose, but with fewer side effects. About 164 people aged 18-45 will be randomly assigned to one of two dose groups. Researchers will track acne…

This pilot study will test whether a daily gummy supplement called Xtressé can safely improve hair growth in 40 men with male pattern baldness. Participants take two gummies each day for six months, and researchers measure changes in hair density and thickness using special camer…

This study tests whether a daily oral minoxidil pill (N1087) can help regrow hair in men with male pattern baldness. About 372 men aged 18 to 60 with moderate hair loss will take either the drug or a placebo for 24 weeks, with the dose slowly increased. The main goal is to see if…

This Phase 3 trial tests a new topical drug called APSMNF for male pattern baldness. About 336 men aged 18 to 60 will apply it twice daily for 24 weeks. Researchers will measure changes in hair density using a special camera and track any side effects.

This study tests whether a treatment called DA-001 can safely reduce hair shedding and promote regrowth in people with certain types of hair loss, including telogen effluvium and female or male pattern baldness. About 1,120 adults will apply the treatment as directed and be monit…

This study tests whether a single injection of nanofat (processed fat from your own body) can treat pattern hair loss better than standard options. Sixty adults with androgenetic alopecia will receive either one nanofat injection, three monthly PRP injections, or daily topical mi…

This study is testing a gel called CABTREO, which combines three acne-fighting ingredients (clindamycin, adapalene, and benzoyl peroxide), in children aged 9 to 11 with moderate to severe acne. The goal is to see if it is safe and works well over 12 weeks. About 100 kids will app…

This study tests three different gels for mild-to-moderate acne: a standard clindamycin-retinoid combo, a clindamycin-retinoid-dexamethasone combo, and a gel made from stem-cell secretions (secretome). About 189 people will use one of the three gels for 8 weeks. Researchers will …

This study tests whether omega-3 supplements or a special anti-demodex eyelid cleanser can help treat and prevent chalazia (styes) in children aged 4 to 17. All 168 participants will use warm compresses, and they will be split into three groups: one adds omega-3 fish oil and stan…

This study tests a daily pill called upadacitinib for people with severe forms of lichen planus, a skin disease causing painful mouth sores or hair loss. About 56 adults will receive either the drug or a placebo for 16 weeks to see if it reduces symptoms. The goal is to control t…

This early-stage study tests two forms of a hair loss drug (AD-303A topical and AD-3031 oral) in 30 men aged 19-55 with male pattern baldness. The goal is to see how the drug moves through the body, how well it works, and if it is safe. The study will help decide the right dose f…

This study tests whether an injection called XVIE, made from processed human amniotic fluid, is safe and might help regrow hair in adults with common pattern baldness. Thirty participants will receive either XVIE or a placebo injected into the scalp, with two treatments 90 days a…

This study tests whether a gel containing methotrexate, an immune-suppressing drug, can regrow hair in people with localized alopecia areata better than minoxidil spray. About 268 adults with less than 25% scalp hair loss will apply one of the two treatments twice daily for 24 we…

This study tests a cream called clascoterone (1%) against a placebo in 692 people aged 12 and older with moderate to severe acne. Participants apply the cream to their face twice daily for 12 weeks. The goal is to see if the cream clears acne better than a placebo, with fewer sid…

This early-stage trial tests a new drug called HB0043, a bispecific antibody that targets two inflammatory proteins (IL-17A and IL-36R) linked to acne. About 21 adults with moderate to severe facial acne will receive either the drug or a placebo. The main goal is to check safety …

This study tests whether a vitamin D-based cream (calcipotriol) works as well as steroid injections for regrowing hair in people with patchy alopecia areata. Sixty adults with less than half their scalp affected will use one of the two treatments for 12 weeks. The goal is to see …

This study tests if intense pulsed light (IPL) is a safe and effective way to treat chalazion, a common eyelid lump. About 40 adults with an inflamed chalazion will receive IPL or a control treatment. The main goal is to see if the lump shrinks by at least 80% four weeks after th…

This study compares two oral medications—tofacitinib and methotrexate—for treating severe alopecia areata, an autoimmune condition causing hair loss. 78 adults aged 18-60 with severe scalp or total body hair loss will take one of the drugs for 12 weeks. The main goal is to see wh…

This study tests two prescription gels—metronidazole and clindamycin—to see which works better for moderate acne. Sixty adults aged 18 to 35 will apply the gel twice daily for 12 weeks. Doctors will check acne severity at the start and at weeks 4, 8, and 12 to measure improvement…

This Phase 3 trial tests whether an oral solution called N1087 can help women with female pattern hair loss regrow hair. About 372 women aged 18 to 60 will receive either N1087 or a placebo daily for 24 weeks. The study measures changes in hair density and thickness using scalp p…

This phase 3 trial is testing whether an oral (pill) form of arsenic trioxide works as well as the standard IV form for consolidation therapy in people with a low-risk type of acute promyelocytic leukemia (APL). About 120 adults and teens who have already completed initial treatm…

This study tests whether adding platelet-rich plasma (PRP) or nanofat injections to standard hair transplants helps more hair grafts survive and grow thicker. Thirty men with stable male pattern baldness will receive both treatments on different scalp areas, and doctors will meas…

This early study will test a new device called the LuSeed Aneurysm Embolization System in 10 people with unruptured brain aneurysms. The device is designed to block blood flow to the aneurysm, reducing the risk of rupture. The main goals are to see if the device is safe and can b…

This study compares two forms of minoxidil—a topical spray and an oral pill—for treating androgenetic alopecia (common hair loss) in 200 men and women aged 18 to 50. Over 6 months, researchers will measure hair regrowth, shedding, and side effects. Participants will use either th…

This study tests biologic drugs for folliculitis decalvans, a rare scalp disease that causes painful pustules and permanent hair loss. Current antibiotics only work about half the time and the condition often returns. The trial will enroll 120 adults who have already tried at lea…

This study tests whether adding a stem-cell-derived exosome solution to fractional laser therapy helps regrow hair better than laser alone. Thirty men with male pattern baldness will receive three laser sessions and be followed for six months. Researchers will measure changes in …

This study compares two medicines, hydroxychloroquine and methotrexate, to see which works better for frontal fibrosing alopecia, a type of scarring hair loss that mainly affects women. About 50 adults who choose to start one of these treatments will be followed for up to 48 week…

This study tests whether platelet-rich plasma (PRP) injections can help treat central centrifugal cicatricial alopecia (CCCA), a scarring hair loss that mostly affects women of African descent. PRP is made from a patient's own blood and is thought to reduce inflammation and promo…

This study aims to train and test artificial intelligence (AI) models to diagnose male and female pattern hair loss (androgenetic alopecia) and assess its severity. Researchers will use images from a handheld dermoscope along with age and sex data from 400 participants. The goal …

This study tests a new treatment called DA-020 to prevent hair loss in people with early-stage breast cancer receiving chemotherapy. About 60 participants will use DA-020 during their chemo sessions. The goal is to see if it can reduce hair loss and help hair grow back faster aft…

This virtual clinical trial will test whether GenLabs' Social Skin products—a cleanser, serum, and cream—can improve acne symptoms and help skin heal better than a placebo. About 150 healthy adults aged 18 to 65 with acne will use the products for 30 days. The main goal is to see…

This early-stage study tests whether platelet-rich plasma (PRP) therapy, made from a participant's own blood, can help women with androgenic alopecia (female pattern hair loss). Sixteen women will receive PRP injections, and researchers will measure changes in hair loss severity …

This study tests whether adding low-level red-light therapy to the standard hair-loss treatment minoxidil helps breast cancer patients regrow hair lost during chemotherapy. About 50 adults with stage I-IV breast cancer who lost at least half their scalp hair after chemo will be e…

This early-phase trial tests a probiotic capsule containing five bacterial strains to treat moderate to severe acne in 34 adults aged 18 to 45. The idea is that improving gut health and reducing inflammation may calm acne breakouts. Researchers will also track blood sugar spikes …

This study tests whether microneedling can improve hair growth in people with mild to moderate pattern baldness. About 25 adults will receive microneedling on one side of their scalp every two weeks for six sessions, while the other side gets no treatment. Researchers will measur…

This small pilot study will test a new type of light therapy for moderate-to-severe acne. A special gel is applied to the face, then activated with red light to kill bacteria and reduce inflammation. Ten people aged 16 and older will receive treatments twice a week. The goal is t…

This study tests whether Xdemvy eye drops can reduce eyelash mite irritation and improve comfort for people who wear special scleral lenses. Five adult lens users with moderate to severe Demodex blepharitis will use the drops and report changes in symptoms like dryness, itching, …

This study tests if a special laser (1726nm) can safely shrink small bumps that appear on the face in people with frontal fibrosing alopecia (FFA). Ten adults with FFA and facial papules will receive the laser treatment. Doctors will measure changes in bump size and number using …

This study tests whether taking oral probiotics for 12 weeks can reduce acne lesions and lower inflammation in people with moderate acne. Researchers will compare probiotics to a placebo in 64 Pakistani participants aged 15-35. The goal is to find a safe, antibiotic-free way to m…

This study tests a new topical gel containing 5% spironolactone against a standard 0.1% adapalene gel for treating acne. Forty people with mild to moderate acne will apply each gel to opposite sides of their face, allowing direct comparison. The goal is to see if the spironolacto…

This study tests if a special cooling cap can reduce hair loss in people with advanced solid tumors who are receiving a type of chemotherapy called antibody-drug conjugates (ADCs). About 102 women will be split into two groups: one gets the cooling cap during treatment, the other…

This study will test whether a gel containing dutasteride, a drug usually used for hair loss, can treat facial acne. Fifty adults with acne will apply the dutasteride gel to one side of their face and either a placebo or a standard triple-combination acne gel to the other side. R…

This study tests a new cream called KR230109 for mild to moderate acne. About 180 people aged 18 to 40 will use the cream or a placebo for 12 weeks. The goal is to see if the cream safely reduces pimples and skin bumps better than no treatment.

This study tests whether letting patients report their symptoms online can help doctors schedule follow-up visits only when needed. About 250 adults with chronic skin conditions like eczema or psoriasis will either get standard fixed appointments or flexible scheduling based on m…

This study is testing a new, non-invasive way to collect and analyze skin oil (sebum) using a simple adhesive patch called Sebutape. Researchers will recruit 200 people, including healthy volunteers and patients with acne, eczema, psoriasis, or seborrheic dermatitis. The goal is …

This early-stage study tests a drug called DA-020 in 60 healthy women aged 18-55. The goal is to measure how much of the drug enters the blood after one application to the scalp and to check for side effects like blood pressure changes. This research helps understand the drug's s…

This study will look at 200 people aged 18 to 25 with mild, moderate, or severe acne, plus healthy volunteers, to understand how acne develops in Singapore's tropical climate. Researchers will analyze skin bacteria, immune responses, and use AI to grade acne from photos. The goal…

This study will collect existing medical records from about 20,000 people aged 12 and older in Italy who have one of five inflammatory skin conditions: psoriasis, atopic dermatitis, vitiligo, alopecia areata, or hidradenitis suppurativa. Researchers want to describe who gets thes…

This study will measure three types of fats (ceramides and S1P) in the blood of 40 people with acne and 40 healthy volunteers. The goal is to see if these fats are different in acne patients and if they relate to acne severity. No treatment is given—just a blood draw. The results…