Acne showdown: which gel wins for clearer skin?

NCT ID NCT07392047

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two prescription gels—metronidazole and clindamycin—to see which works better for moderate acne. Sixty adults aged 18 to 35 will apply the gel twice daily for 12 weeks. Doctors will check acne severity at the start and at weeks 4, 8, and 12 to measure improvement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
metronidazole gel 2% and clindamycin gel 1%
What this could lead to
If one gel works better, it could offer a new or cheaper option for treating moderate acne.
What could go wrong
This is a small, early-phase trial with only 60 people, so results may not apply to everyone. Both gels can cause skin irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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