Head-to-Head: which acne cream works better for clear skin?
NCT ID NCT07673094
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study compares two topical medications—clascoterone cream and adapalene gel—for treating mild acne vulgaris. Researchers will enroll 60 people aged 12 to 35 with mild acne and randomly assign them to use one of the treatments for 12 weeks. The goal is to see which treatment leads to clearer or almost-clear skin, helping doctors make better treatment choices.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- clascoterone cream 1% and adapalene gel 0.1%
- What this could lead to
- If one treatment proves more effective, it could help dermatologists choose the best topical option for mild acne, improving skin clearance and patient satisfaction.
- What could go wrong
- This is a small, early-phase study with only 60 participants, so results may not apply broadly. Both treatments may cause skin irritation or allergic reactions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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