Head-to-Head: which acne cream works better for clear skin?

NCT ID NCT07673094

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study compares two topical medications—clascoterone cream and adapalene gel—for treating mild acne vulgaris. Researchers will enroll 60 people aged 12 to 35 with mild acne and randomly assign them to use one of the treatments for 12 weeks. The goal is to see which treatment leads to clearer or almost-clear skin, helping doctors make better treatment choices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

clascoterone cream 1% and adapalene gel 0.1%

What this could lead to

If one treatment proves more effective, it could help dermatologists choose the best topical option for mild acne, improving skin clearance and patient satisfaction.

What could go wrong

This is a small, early-phase study with only 60 participants, so results may not apply broadly. Both treatments may cause skin irritation or allergic reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACNE VULGARIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••