Lichen planopilaris
MONDO:0018879Lichen planopilaris (LPP) is a rare cutaneous variant of lichen planus which affects hair follicles. It may occur on its own or in association with more common forms of lichen planus, usually classical type and/or oral lichen planus.
Also known as: LPP, follicular lichen planus, lichen follicularis, lichen planus follicularis, Kossard disease, frontal fibrosing alopecia (subtype), lichen planopilaris classic type
4 clinical trials for this condition and its sub-types.
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Could a cream stop scarring hair loss? small trial begins
Disease control Recruiting nowThis pilot study tests a topical cream called delgocitinib in 30 adults with two types of scarring hair loss: lichen planopilaris and central centrifugal cicatricial alopecia. Participants apply the cream twice daily for 48 weeks. The study focuses on safety and changes in immune…
Phase: PHASE2 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New pill could stop scalp scarring and hair loss
Disease control Recruiting nowThis study tests an oral medication called brepocitinib for adults with lichen planopilaris, a condition that causes scalp inflammation, scarring, and hair loss. About 342 participants will receive either the drug or a placebo to see if it reduces symptoms and improves scalp appe…
Phase: PHASE2, PHASE3 • Sponsor: Priovant Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New drug may stop scalp scarring and hair loss
Disease control Recruiting nowThis pilot study tests nemolizumab, a drug already approved for other skin conditions, in 10 adults with lichen planopilaris (LPP), a disease that causes permanent hair loss and scalp itching or burning. The goal is to see if the drug can reduce disease activity and improve sympt…
Phase: PHASE4 • Sponsor: The Skin Center Dermatology Group • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC