Can a Two-Drug punch shrink eyelid tumors before surgery?

This trial is testing whether giving two drugs—sintilimab and disitamab vedotin—before surgery can shrink tumors in people with a rare type of eyelid cancer called sebaceous gland carcinoma. Participants receive two cycles of the combination, then undergo surgery to remove the tumor, followed by up to a year of maintenance therapy with sintilimab alone. The study aims to see how many patients have a major or complete response in the tumor tissue after this pre-surgery treatment, and to assess safety and how long patients stay cancer-free.