New acne cream could be Game-Changer for teens and adults

NCT ID NCT07457294

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a cream called clascoterone (1%) against a placebo in 692 people aged 12 and older with moderate to severe acne. Participants apply the cream to their face twice daily for 12 weeks. The goal is to see if the cream clears acne better than a placebo, with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
1% clascoterone cream
What this could lead to
If it works, this could provide a new topical treatment option for moderate to severe acne, reducing pimples and skin inflammation.
What could go wrong
This is a Phase 3 trial, but it hasn't started yet. The cream may not work better than placebo, and side effects like skin irritation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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