Hair loss showdown: methotrexate gel vs minoxidil spray in new trial

NCT ID NCT07459933

First seen Mar 17, 2026 · Last updated May 17, 2026 · Updated 7 times

Summary

This study tests whether a methotrexate gel applied to the scalp can regrow hair better than the standard minoxidil spray in people with localized alopecia areata (patchy hair loss). About 268 adults aged 18-50 with less than 25% scalp hair loss will use one of the two treatments for 24 weeks. The goal is to see which treatment reduces hair loss more effectively.

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