University Of Illinois At Chicago

This small study tested whether 4 weeks of high-intensity breathing exercises (inspiratory muscle training) could improve blood vessel health in 11 adults with heart disease, such as those who had bypass surgery. Participants either did the real breathing workout or a sham versio…

This study tested a smartphone app called 'My Personal Health Guide' that uses a friendly, talking avatar to help HIV-positive African American men (ages 18-34) stick to their medication and keep up with doctor visits. The goal was to see if the app could improve viral suppressio…

This study looked at whether smokers who want to cut back can switch to a special research e-cigarette. Over 12 weeks, 63 participants tried to reduce their regular cigarette use. Researchers tracked how many cigarettes they smoked, any health changes, and how well they liked the…

This study looked at whether alternating between a day of fasting and a day of normal eating, combined with exercise, can reduce liver fat in people with non-alcoholic fatty liver disease (NAFLD). The trial included 80 obese adults who were not very active. Researchers measured c…

This early-phase study tested a combination of two drugs (venetoclax and omacetaxine) in 6 adults with acute myeloid leukemia (AML) whose cancer had stopped responding to venetoclax. The goal was to find a safe dose and see if the combo could shrink the cancer. The study was smal…

This study tested whether combining continuous glucose monitors with monthly telehealth appointments with a pharmacist could help people with uncontrolled type 2 diabetes. 46 adults from a community health center took part. Researchers measured blood sugar levels and surveyed par…

This study looked at whether eating only during an 8-hour window each day (time-restricted eating) helps young adult survivors of childhood cancer manage their weight. Thirteen survivors aged 18-39 with a BMI between 25 and 40 took part. The goal was to see if this eating pattern…

This study looked at whether giving head and neck cancer patients a special nutritional drink (Nestle Impact Advanced Recovery) before and after major surgery could lower the chance of wound problems like infections or fluid buildup. Only 4 adults took part, all scheduled for maj…

This study compared time-restricted eating (eating only during a 6-8 hour window each day) to daily calorie restriction for weight loss and blood sugar control in 32 adults with type 1 diabetes and obesity. Participants followed their assigned diet while continuing insulin and gl…

This study looked at whether the Big Brothers Big Sisters community-based mentoring program can help prevent crime and juvenile delinquency in youth ages 10 to 16. Over 1,300 participants were randomly assigned to either receive mentoring or not, and their outcomes were tracked f…

This study tested whether taking a daily supplement of lactoferrin, a protein found in cow's milk, could help prevent iron deficiency anemia in pregnant women with obesity. 23 women at risk for anemia took part. The main goal was to see if the approach was practical and acceptabl…

This study tested a mobile app called WeCanManage designed to help cancer survivors with disabilities manage long-term effects of their illness and treatment. Twenty adults who had breast cancer, head and neck cancer, or sarcoma participated. The goal was to see if the app was ea…

This study looked at whether high-intensity walking exercise can reduce fatigue and improve walking in people with multiple sclerosis (MS). Twelve adults with MS who had walking difficulties and significant fatigue took part. They completed a high-intensity gait training program,…

This study tested whether a computer program called PAINRelieveIt could help hospice patients with cancer and their caregivers better manage pain. About 250 patient-caregiver pairs took part, with some using the program and others receiving usual care. The goal was to see if the …

This study tested whether an AI voice coach called Lumen can help adults with mild-to-moderate depression and anxiety. About 200 participants were randomly assigned to receive problem-solving coaching from Lumen, a human coach, or a waitlist. The goal was to see if the AI coach c…

This study tested whether a 4-month exercise program done at home could help Hispanics/Latinos with multiple sclerosis (MS) feel better and move easier. Participants worked with coaches via video calls to do flexibility, aerobic, and resistance exercises. The goal was to see if t…

This study tested whether guided relaxation and acupuncture can reduce pain and opioid use in 379 adults with sickle cell disease. Participants were randomly assigned to one of these therapies or usual care, and researchers tracked pain levels, sleep, anxiety, and mood over six w…

This study tested a 6-week program called Heart Up! that uses text messages and support from nurses and loved ones to help adults with heart disease become more physically active and feel less hopeless. About 224 patients who had a heart attack or related procedure took part. The…

This study tested a 6-week program called BUILT for families with children aged 6-12 who have ADHD. The program aimed to improve sleep, nutrition, and exercise habits to help with focus and behavior. 69 children took part, and researchers measured changes in physical activity, sl…

This study tested whether a digital program to help young adults (ages 18-30) sleep longer could also improve their mood. Nineteen participants with mild mood and sleep problems received weekly phone coaching and educational materials for six weeks. Their sleep was tracked with a…

This early-phase study tested the safety of eye drops made from stem cell secretions (secretome) in 9 adults with chronic corneal damage and reduced eye sensation. The goal was to find the highest safe dose and see if it helps heal the cornea's surface. Participants received incr…

This study tested whether a smartphone app that tracks how you type can help monitor mood and thinking problems in people with mood disorders like depression or bipolar disorder. About 132 adults aged 25-50 participated. The goal was to see if typing patterns could predict sympto…

This study looked at 124 women with recent suicidal thoughts to understand how natural hormone changes during the menstrual cycle might increase suicide risk. Researchers used a two-week hormone-stabilizing treatment to see if it could reduce suicidal thinking around the time of …

This study looked at how different diets affect gut bacteria and markers of colon cancer risk in 15 African American adults at higher risk for the disease. Participants ate both a high-fat, animal-based diet and a low-fat, plant-based diet to see which one reduced harmful bacteri…

This study tested a program for parents of young children from low-income families. The program was delivered during regular doctor visits and aimed to help parents talk, read, and play more with their babies. 60 parents took part to see if the program was easy to use and if it i…

This study looked at whether teens on probation would use a meditation app for one month and if researchers could collect data remotely on their cannabis use, sexual health, and mental health. 107 youth aged 13-18 took part. The goal was to see if this approach is feasible, not t…

This study tested a website designed to help people with advanced cancer and their family caregivers have conversations about future medical care. Researchers worked with 36 participants to see how they used the tool and gathered their feedback to improve it. The goal was to make…

This study tested a technique called ischemic conditioning, which uses a blood pressure cuff to briefly restrict blood flow to the leg, to see if it could improve brain activity and movement in people who had a stroke. Twenty participants with stroke completed two sessions, one w…

This study looked at people with narrowed or blocked arteries in the back of the brain, which can cause strokes or mini-strokes. Researchers used MRI scans to measure blood flow and see if those with low flow had a higher chance of another stroke. The goal was to better understan…

This study looked at how Chinese American patients with cancer or heart disease and their families discuss advance care planning. Researchers interviewed religious leaders and surveyed community members in Chicago to understand what support people need. The goal is to create a cu…

This study tested new guidelines for PSA screening in 49 men aged 40-75 with elevated PSA levels. The goal was to improve how doctors decide when to start and stop screening, how often to repeat it, and when to refer for biopsy. Researchers compared PSA test rates, biopsy complic…

This study looked at whether practicing mindfulness can reduce chronic stress and lower colon cancer risk factors in Black women aged 45-65 who live in high-crime Chicago neighborhoods. Twenty-four women who had a past colon polyp and reported high stress took part. The goal was …