University Of Illinois At Chicago

This study tests whether adding a precise, high-dose radiation to the marrow (total marrow irradiation) to standard chemotherapy before a donor stem cell transplant can help people with high-risk acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) live longer without …

This study tests whether curcumin, the active ingredient in turmeric, can improve blood vessel and brain function in kidney transplant recipients. Fourteen adults who received a kidney transplant will take curcumin or a placebo for 12 months. Researchers will measure kidney funct…

This study looks at whether different types of messages sent through a patient portal can encourage smokers to get free coaching from the Illinois Tobacco Quitline. About 3,000 adult smokers from several health centers will be randomly assigned to receive one of three messages. T…

This study tests a video-based healthy lifestyle program for adults aged 50 to 74 who are overweight and have conditions like prediabetes, diabetes, or high blood pressure. Participants use a tablet and fitness tracker at home, and some get extra support from a coach by video or …

This study compares time-restricted eating (eating only during a set daily window) to traditional calorie counting for weight loss and reducing colorectal cancer risk. About 193 adults with obesity, aged 45-70, will follow one of the two diets for a period. The goal is to see if …

This study tests a program called CATCH-IT, designed to prevent depression in teenagers aged 13-18 who have mild symptoms or a past episode but are not currently depressed. The program is delivered through primary care and uses a behavioral "vaccine" approach. Researchers will wo…

This early-stage study tests a group healthcare program called Centering PrEP+ for sex workers in Chicago. The goal is to see if this approach is acceptable and practical for increasing PrEP use and adherence to prevent HIV. About 24 sex workers and clinic staff will take part in…

This study looks at whether a multi-family therapy program can help teenagers with anorexia and their families. About 200 teens aged 11-18 and their parents will take part in group sessions to learn skills for meal support and managing emotions. The goal is to see if this approac…

This study looks at whether adding a gentle brain stimulation technique (tDCS) to personalized physical therapy can better relieve chronic knee pain and improve movement compared to physical therapy alone. About 30 adults with knee pain lasting over 3 months will receive either r…

This study tests whether a 1-month meditation app can help juvenile justice officers and others working with court-involved youth feel less stressed, anxious, or burned out. About 57 adults who work directly with these youth will use the app and report how acceptable and helpful …

This study tests a 16-week home-based exercise program for people diagnosed with multiple sclerosis within the last two years. The goal is to see if the program helps them become more active and improves fatigue, mood, and quality of life. Participants wear an activity tracker an…

This study tests a program to help adults with serious mental illness learn more about their immune health and adopt healthier habits. Around 100 participants from community mental health agencies will take part. The goal is to see if the program improves how they feel and manage…

This study looks at whether adding AI-enhanced images during single-port robotic surgery helps lower the mental workload for surgeons and their assistants. About 90 urology surgeons and residents will take part. The goal is to see if real-time AI overlays make complex procedures …

This study aims to find brain-based markers that predict whether depression will return in older adults. Researchers will measure stress reactions and brain network activity in 210 people aged 60 and older, some currently depressed and some in remission. The goal is to understand…

This study was designed to see if GLP-1 medications change how stiff arteries become after exercise in people with type 2 diabetes. It planned to measure artery stiffness and blood pressure during a treadmill test. The study was withdrawn before enrolling any participants, so no …

This study tests a program called Preschool and Me (PreM) that connects doctors and schools to help children aged 3-5 with developmental delays get special education services. About 320 parent-child pairs will join to see if the program improves access to therapies and school pro…

This study tests whether a walking program using fitness trackers and social networking is practical and helpful for older adults (ages 35-60) with mild to moderate intellectual disabilities. Participants will wear a Fitbit, receive text reminders, and get support from family or …