New radiation method aims to boost survival in tough blood cancers

This study tests whether adding a precise, high-dose radiation to the marrow (total marrow irradiation) to standard chemotherapy before a donor stem cell transplant can help people with high-risk acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) live longer without the cancer returning. About 38 adults aged 18 to 65 with hard-to-treat forms of these diseases will receive the treatment. The goal is to see if at least 18 out of 46 patients survive one year without relapse, which would suggest the approach is worth further study.