University Of Illinois At Chicago
Clinical trials sponsored by University Of Illinois At Chicago, explained in plain language.
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New hope to shield kidneys in sickle cell disease
Disease control Not yet recruitingThis study is testing if a drug called empagliflozin can help protect the kidneys of people with sickle cell anemia. It will involve 20 adults who already show early signs of kidney damage. Researchers will measure changes in urine and blood tests, and use a special kidney scan, …
Phase: PHASE2 • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Common allergy drug may boost brain repair in older adults with depression
Disease control Not yet recruitingThis study is testing whether adding the antihistamine clemastine to standard antidepressant treatment can improve brain structure and help depression treatment work better in adults over 60. Researchers will compare two groups—one receiving antidepressants with clemastine and on…
Phase: PHASE2 • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Virtual nurse support aims to stop silent kidney damage in diabetics
Disease control Not yet recruitingThis study tests whether a virtual meeting with a nurse before a doctor's visit can help people with diabetes and early kidney disease. The nurse provides education, motivation, and connects people to support services. Researchers want to see if this approach helps patients bette…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Double attack on deadly brain bleeds: surgery meets drug in groundbreaking trial
Disease control Not yet recruitingThis study tests whether combining a minimally invasive surgery to remove a brain bleed with an intravenous drug (deferoxamine) works better than standard medical care alone. It aims to improve recovery and reduce disability in 240 adults who have recently suffered a spontaneous …
Phase: PHASE2, PHASE3 • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Can a fitbit help young people with psychosis get healthier?
Disease control Not yet recruitingThis study is testing a wellness program for young adults recently diagnosed with conditions like schizophrenia. The program combines Fitbit activity trackers with health coaching to help participants improve their sleep and get more physical activity. Researchers will enroll abo…
Phase: PHASE1 • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Could a probiotic pill be a gentler fix for pregnancy anemia?
Disease control Not yet recruitingThis study is testing if a daily probiotic supplement can help pregnant women at risk for low iron absorb iron better from their diet and improve their blood health. Researchers want to see if this approach is more comfortable and effective than standard iron pills, which can cau…
Phase: PHASE2 • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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New program aims to keep kids with feeding tubes out of the ER
Disease control Not yet recruitingThis study is testing a new, structured education program for parents whose children are being sent home from the hospital with a feeding tube. The goal is to see if better training and support for parents leads to fewer emergency room visits and gives families more confidence in…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Can prescription meals cure high blood pressure?
Disease control Not yet recruitingThis study is testing whether a 'food is medicine' program can help adults with high blood pressure and obesity. For 24 weeks, half the participants will receive weekly deliveries of heart-healthy meals and cooking lessons, while the other half receives usual care. Researchers wa…
Phase: PHASE2 • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Mar 11, 2026 14:54 UTC
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Fast lifting for a sharp mind: new study tests exercise as brain shield against dementia
Prevention Not yet recruitingThis study is testing whether a 12-week program of fast-paced strength training can improve brain health in older adults at risk for Alzheimer's disease. Researchers want to see if this specific type of exercise improves blood flow to the brain and thinking skills like memory and…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Prevention
Last updated Apr 03, 2026 20:10 UTC
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New hope: local nurses and peers join forces to stop suicide
Prevention Not yet recruitingThis study aims to test a new suicide prevention program for women in Tajikistan. The program, called SUSTAIN, will be led by nurses and trained peers in local health clinics. Researchers will enroll 96 women at moderate to high risk of suicide to see if the support program can r…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Prevention
Last updated Mar 30, 2026 14:33 UTC
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Can playing a video game stop dementia? new study tests Brain-Body training
Prevention Not yet recruitingThis study is testing a new computer-based exercise game designed to help prevent dementia in older adults with mild memory problems. Researchers want to see if combining physical movement with mental challenges in a fun, video-game format can improve balance, thinking skills, an…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Prevention
Last updated Mar 27, 2026 12:38 UTC
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New approach: community health workers tackle mental health in Spanish-Speaking families
Symptom relief Not yet recruitingThis study is testing whether community health workers can effectively deliver a mental health support program to Spanish-speaking Latine parents experiencing depression, anxiety, or traumatic stress. Researchers will enroll 52 parents and randomly assign them to receive the 14-w…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Can an 8-Hour eating window ease chemo side effects?
Symptom relief Not yet recruitingThis study is testing whether time-restricted eating—consuming all daily food within an 8-hour window—is practical and helpful for people undergoing chemotherapy for breast cancer. Researchers will enroll 40 women to compare different eating schedules over 24 weeks. The main goal…
Phase: PHASE1 • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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New therapy tested to help struggling moms after birth
Symptom relief Not yet recruitingThis study is testing whether a 6-week therapy program can help new mothers who are experiencing depression and drinking alcohol. Researchers will enroll about 30 mothers within their first year after giving birth. Half will receive the therapy sessions, while the other half will…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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New program aims to ease tough talks about cancer care
Symptom relief Not yet recruitingThis study is testing a web-based program called ROCKS, designed to build resilience and help patients with advanced cancer and their family caregivers have important conversations about future care wishes. Researchers will see if the program helps people complete advance directi…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Can home workouts ease Parkinson's symptoms? new study tests remote coaching
Symptom relief Not yet recruitingThis study is testing whether a 16-week home exercise program, guided by a coach over video calls, can help people with Parkinson's disease. Fifty participants who are not currently very active will be randomly assigned to either do aerobic and strength exercises or a stretching …
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Brain scans probe why drugs hit people differently
Knowledge-focused Not yet recruitingThis study aims to understand why people's moods, behaviors, and brain responses vary after using recreational drugs like cannabis. Researchers will use brain scans (fMRI) and computer tasks to measure how young adults anticipate rewards and learn from them. The goal is to gather…
Phase: EARLY_PHASE1 • Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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AI predicts your cancer risk: how do patients react?
Knowledge-focused Not yet recruitingThis study aims to understand how patients feel and what they believe after an artificial intelligence (AI) tool tells them their personal risk of developing lung cancer in the next three years. Researchers at the University of Illinois will enroll up to 400 current or former hea…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:56 UTC
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Could your kitchen be fogging your brain? study tests cooking fumes
Knowledge-focused Not yet recruitingThis study aims to understand the immediate effects of breathing in tiny particles from cooking on lung function and memory. Healthy adults will spend time in a controlled room on two days: one with clean air and one where researchers cook a meal. The goal is to measure changes i…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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AI tool aims to spot lung cancer risk earlier
Knowledge-focused Not yet recruitingThis study is testing whether an artificial intelligence tool called Sybil can better predict who is at risk for lung cancer. Researchers will enroll 2,500 current or former smokers aged 50-80 to see if using Sybil and expanded screening rules can find more at-risk people than cu…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Apple watches reveal hidden stress in dental students
Knowledge-focused Not yet recruitingThis study aims to understand how stressful it is for dental students to treat patients, especially those with special needs. Researchers will have 10 dental students wear Apple Watches during about 200 routine patient appointments to track their heart rates. The goal is to compa…
Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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New program aims to bridge communication gap in oral cancer care
Knowledge-focused Not yet recruitingThis study is creating and testing a new communication tool designed to help dentists talk with Black men about oral cancer. Researchers will work with community members to make the tool culturally appropriate, then test it with both dentists and patients. The goal is to see if t…
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:24 UTC