University Of Illinois At Chicago

This study tests whether providing healthy foods and cooking lessons can help adults with high blood pressure and obesity lower their blood pressure and lose weight. About 150 participants will either receive the food program or standard care for 24 weeks. The goal is to see if t…

This study tests whether combining a small surgery to remove blood clots from the brain with a drug called deferoxamine can help people recover better after a brain bleed. About 240 adults with moderate to severe bleeding will be randomly assigned to get the combo treatment or st…

This study tests whether empagliflozin, a drug already approved for kidney disease in diabetes, can slow kidney damage in people with sickle cell anemia. Researchers will enroll 20 adults with sickle cell disease and early signs of kidney trouble. Participants will take the drug …

This study tests a new program that combines thinking exercises with physical movement to help older adults with mild memory problems. The goal is to improve balance, activity levels, and quality of life, and to slow or prevent progression to dementia. Forty-six participants aged…

This study looks at whether a 12-week high-velocity resistance training program can improve thinking skills and brain blood flow in adults aged 60 to 79 who are at higher risk for Alzheimer's disease. Participants will be randomly assigned to either the exercise program or their …

This study tests a program called ROCKS to help people with advanced cancer and their family caregivers talk about and plan for future medical care. About 152 patient-caregiver pairs will be randomly assigned to the program or usual care. The goal is to see if the program helps m…

This study tests a program called On Track for Wellness that gives Fitbit activity trackers and health coaching to people recently diagnosed with psychosis. The goal is to help them increase daily steps and improve sleep. About 365 people from Illinois early psychosis programs wi…

This study tests a new program called SUSTAIN, where nurses and trained peers provide support to women at moderate or high risk of suicide in Tajikistan. About 96 women will take part, with half receiving the program and half getting usual care. The goal is to see if this approac…

This study will develop and test a digital mental health program called 'VIBE in the Parks' for teens and young adults (ages 13-24) who use Chicago Park District programs. About 268 participants will be split into two groups: one gets the VIBE program, the other gets a digital wo…

This pilot study looks at whether a 6-week program that combines problem-solving therapy with small rewards can help new mothers feel less depressed and drink less alcohol. About 30 mothers within a year of giving birth will take part. Half will get the program; the other half wi…

This study tests a 16-week home-based exercise program for 50 people with Parkinson's disease who are not very active. Participants will either do aerobic and resistance training or simple stretching, all guided by a coach through video chats. The goal is to see if the program in…

This study looks at whether community health workers (CHWs) can effectively deliver a mental health program to Spanish-speaking Latine parents who have symptoms of depression, anxiety, or traumatic stress. About 52 parents will either get the program right away or after a 5-month…

This study tests whether a low dose of olanzapine, a drug often used for nausea, can help people with stomach cancer maintain their weight and appetite while receiving chemotherapy before surgery. About 26 participants will be randomly assigned to receive either olanzapine plus s…

This study tests whether clemastine, a common antihistamine, can improve brain white matter and make antidepressants work better in older adults (over 60) with depression. About 80 participants will receive either clemastine or a placebo alongside their antidepressant. The goal i…

This study will test whether a 16-week Pilates program done at home via video calls can improve walking, balance, fatigue, and pain in people with multiple sclerosis (MS). About 50 adults with mild to moderate MS will be assigned to either the Pilates group or a waitlist. Researc…

This pilot study will test if a program that provides education, motivation, and social support can help prevent kidney disease from worsening in 50 adults with diabetes and early-stage chronic kidney disease. Participants will meet virtually with a nurse and complete surveys ove…

This study will have about 12 endodontists (root canal specialists) wear an Apple Watch during routine procedures to track their heart rate changes. A researcher will note when different steps happen, like numbing or drilling, to see which parts are most stressful. The goal is si…

This study looks at how tiny particles from cooking (like frying and grilling) affect healthy adults' memory, thinking speed, and lung function. Fifteen participants will spend two 6-hour sessions in a special room—one with clean air and one with cooking fumes—to compare the effe…

This study aims to find out how much audio delay people can tolerate when using wireless remote microphones, like those in smartphones. Researchers will test 60 adults with normal hearing to measure annoyance from delays in their own voice and external sounds. The results will he…

This study aims to find better ways to decide when patients can safely go home alone after anesthesia, without needing a friend or family member to drive them. Researchers will test custom phone apps and thinking tests in 1,000 adults who are staying in the hospital for 23 hours …

This study will have 10 dental students wear an Apple Watch to track their heart rate and stress while treating both special-needs and non-special-needs patients. Researchers want to see if treating special-needs patients causes more stress. The study does not test any treatment …

This study tests a new program to help families of children with feeding tubes (like G-tubes or NG-tubes) prepare for going home from the hospital. The program provides extra education and ensures all supplies and appointments are ready before discharge. Researchers will compare …

This study looks at how mood, behavior, and brain activity change in young adults (ages 18-21) who use cannabis. Researchers will use brain scans and questionnaires to understand why some people respond differently to the same drug. The goal is to learn more about individual diff…

This study tests a communication tool to help dentists talk with Black men about oral and throat cancers. About 50 Black men will fill out surveys before and after an oral cancer screening. The goal is to see if the tool improves understanding and comfort during these conversatio…

This study will test a new care system for people with opioid use disorder across a large health network in Chicago. Researchers want to see if the system increases screening, helps patients stay in care, boosts use of medication, and reduces opioid-related deaths. Over 270,000 p…