University Of California, Irvine
Clinical trials sponsored by University Of California, Irvine, explained in plain language.
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Can a few classes help people stick to their blood pressure pills?
Disease control CompletedThis study tested whether personalized educational sessions could help adults with uncontrolled high blood pressure take their medication more consistently. It involved 511 Hispanic adults who were randomly assigned to one of two educational programs. Researchers tracked if parti…
Phase: NA • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Early trial tests cholesterol pill to boost leukemia fight
Disease control CompletedThis early-stage study tested the safety of adding a common cholesterol-lowering drug (pitavastatin) to a standard leukemia treatment (venetoclax). It involved 6 adults with either chronic lymphocytic leukemia (CLL) or acute myeloid leukemia (AML). The main goal was to find the s…
Phase: PHASE1 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Mind-Controlled therapy helps stroke survivors walk again
Disease control CompletedThis study tested a new rehabilitation therapy for people who have difficulty walking after a stroke. It combined a brain-computer interface, which reads brain signals, with functional electrical stimulation, which activates leg muscles. The goal was to see if this high-tech ther…
Phase: NA • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Can a 5-Day fast help control rising blood sugar?
Disease control CompletedThis small, completed pilot study tested whether a special 5-day, low-calorie 'fasting-mimicking' diet is a practical approach to study for managing prediabetes in Asian American adults. The main goal was to see if people could stick to the diet and if researchers could run a lar…
Phase: NA • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Drugs before surgery aim to make kidney stone removal safer and faster
Disease control CompletedThis study tested whether taking certain medications before kidney stone surgery could help doctors safely place a larger working tube in the ureter. 220 adults scheduled for stone removal were randomly assigned to receive one of two drugs (tadalafil or tamsulosin), both together…
Phase: PHASE4 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Mar 11, 2026 14:52 UTC
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New program aims to close gaps in Life-Saving lung cancer checks
Prevention CompletedThis study tested a program designed to help more eligible patients get screened for lung cancer. It involved reminding doctors, educating patients, offering financial help, and prompting discussions during check-ups. The goal was to see if this approach led to more people gettin…
Phase: NA • Sponsor: University of California, Irvine • Aim: Prevention
Last updated Mar 30, 2026 14:35 UTC
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Scientists scan teen brains to stop risky behavior before it starts
Prevention CompletedThis study tested how a family-based program affects the developing brain to help prevent risky behaviors in African-American teens. Researchers used brain scans and questionnaires to see if the 6-week program changed how the brain handles rewards and self-control. The goal was t…
Phase: NA • Sponsor: University of California, Irvine • Aim: Prevention
Last updated Mar 23, 2026 15:15 UTC
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Hospital trial aims to clear deadly superbug from patients
Prevention CompletedThis study tested if a special hygiene regimen could prevent dangerous MRSA infections in people who carry the bacteria after leaving the hospital. Over 2,100 high-risk patients were randomly assigned to receive either the intensive hygiene treatment or standard hygiene education…
Phase: NA • Sponsor: University of California, Irvine • Aim: Prevention
Last updated Feb 23, 2026 14:50 UTC
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New study tests simple arm exercise device to boost stroke recovery
Symptom relief CompletedThis study tested two ways to add extra arm exercise to standard stroke rehabilitation. Researchers compared a customized hand-and-arm exercise program to using a movable wheelchair armrest that helps move the arm back and forth. The goal was to see which method better improved a…
Phase: NA • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Apr 03, 2026 14:46 UTC
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Smartphone app aims to ease cancer pain for kids at home
Symptom relief CompletedThis study tested a smartphone app called Pain Buddy, designed to help children with cancer manage pain and other symptoms while receiving outpatient chemotherapy. The app allowed kids to track their symptoms daily and provided coping skills training. Researchers aimed to see if …
Phase: NA • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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One poke or ten? study tests simpler bladder botox
Symptom relief CompletedThis study tested whether giving a standard Botox dose for overactive bladder through just one injection works as well as spreading it across ten injections. Researchers wanted to see if the single-injection method was just as effective at reducing symptoms while potentially caus…
Phase: PHASE4 • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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Virtual support program aims to ease burden for latino families facing childhood cancer
Symptom relief CompletedThis study tested a 13-week virtual support program designed specifically for Spanish-speaking Latino caregivers of children recently diagnosed with cancer. The program included cooking, gardening, movement, and educational sessions to help reduce stress and improve quality of li…
Phase: NA • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Puppy power: can dogs unlock calm for kids with ADHD?
Symptom relief CompletedThis small, completed study tested if adding therapy dogs to standard social skills training could help children with ADHD. Researchers compared the dog-assisted program to training alone, looking for improvements in behavior and self-esteem. They also collected saliva samples to…
Phase: NA • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Mar 20, 2026 14:48 UTC
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Scientists study Kids' exercise patterns to create better fitness tests
Knowledge-focused CompletedThis study aims to understand how different exercise types affect heart and lung health in children and young adults. Healthy participants aged 7-35 will perform various exercises on stationary bikes and treadmills. The research seeks to develop better fitness assessment methods …
Phase: NA • Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Apr 03, 2026 19:56 UTC
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Scientists probe why stress hits some teens harder, fuels obesity
Knowledge-focused CompletedThis study aimed to understand why obesity rates differ among racial groups, focusing on African-American, Hispanic, and White teenage girls. Researchers examined how stress influences food choices and physical activity in both everyday life and controlled lab settings. The goal …
Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Diet soda showdown: does your favorite Zero-Calorie drink help or hurt diabetes?
Knowledge-focused CompletedThis study aimed to find out if drinking diet sodas or water is better for people managing type 2 diabetes. Researchers followed 181 adults with diabetes for 24 weeks, having one group drink three servings of diet soda daily and another drink three servings of water. They measure…
Phase: NA • Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC