Colgate Palmolive
Clinical trials sponsored by Colgate Palmolive, explained in plain language.
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New toothpaste and mouthwash combo fights plaque and gum disease
Disease control CompletedThis study tested whether using a special stannous fluoride toothpaste, a cetylpyridinium chloride mouthwash, and a battery-powered toothbrush together can reduce dental plaque and gum inflammation (gingivitis) over 12 weeks. A total of 134 adults aged 18 to 70 with at least 20 n…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 08:48 UTC
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New toothpaste and mouthwash combo takes on gingivitis
Disease control CompletedThis study tested whether a special dental routine (PerioGard toothpaste, mouthwash, and toothbrush) works better than standard products at reducing gum inflammation and plaque. 80 adults with mild to moderate gingivitis used one of the two routines for three months. The goal was…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 08:46 UTC
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Floss vs. mouthwash: which wins the battle against plaque and gum disease?
Disease control CompletedThis study tested how well floss and three different mouthwashes (essential oil with alcohol, essential oil without alcohol, and CPC+Zn without alcohol) reduce dental plaque and gum inflammation. 228 adults with mild to moderate gum disease took part. The goal was to see which me…
Phase: PHASE4 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 08:45 UTC
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Toothpaste plus mouthwash beats regular brushing in gum health showdown
Disease control CompletedThis study tested whether using a special toothpaste with mouthwash and a manual toothbrush works better than regular fluoride toothpaste for reducing plaque and gum problems. 90 adults aged 18-70 with mild gum disease and plaque took part over 12 weeks. Researchers measured plaq…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 08:35 UTC
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Tartar-Fighting toothpaste put to the test in bangkok study
Disease control CompletedThis study compared a toothpaste with stannous fluoride to a regular fluoride toothpaste for controlling tartar (hardened plaque) on teeth. About 100 adults in Bangkok used one of the two toothpastes for 12 weeks. Researchers measured tartar buildup to see if the stannous fluorid…
Phase: PHASE2, PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 08:35 UTC
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Battery toothbrush takes on plaque and gingivitis in 12-Week trial
Disease control CompletedThis study tested whether a battery-powered toothbrush, used with toothpaste, can reduce plaque and gum inflammation (gingivitis) in adults. 130 healthy adults with mild to moderate gum disease and plaque used the toothbrush for 12 weeks. Dentists measured plaque and gum health a…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 26, 2026 08:19 UTC
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Zinc toothpaste takes on gum disease in Head-to-Head trial
Disease control CompletedThis study tested whether a new Colgate toothpaste with two types of zinc can better control plaque and gingivitis (gum inflammation) compared to a standard cavity-protection toothpaste. 86 adults with mild to moderate gum issues used one of the two toothpastes for three months. …
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New toothpaste and brush combo takes on plaque and gum disease
Disease control CompletedThis study compared a stannous fluoride toothpaste paired with a newly designed toothbrush to a standard toothpaste and brush for reducing plaque and gingivitis. 95 adults in Thailand used their assigned products for three months. Researchers measured plaque and gum health at the…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New mouthwash fights plaque and gum trouble on implants
Disease control CompletedThis study tested whether a new mouthwash with CPC, hyaluronic acid, and zinc lactate can reduce plaque and prevent gum problems around dental implants better than a standard fluoride mouthwash. 80 adults with at least two dental implants used the mouthwash for 6 months. The goal…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Toothbrush showdown: which brush beats plaque?
Disease control CompletedThis study tested how well manual toothbrushes reduce plaque and gingivitis (gum inflammation). 84 adults brushed at home with one of two toothbrushes for 6 weeks. Dentists checked their teeth and gums at the start and after 1, 3, and 6 weeks to see how much plaque and gum swelli…
Phase: PHASE2 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 20, 2026 12:08 UTC
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Special toothpaste and mouthwash take on plaque and gingivitis in new study
Disease control CompletedThis study tested whether using a stannous fluoride toothpaste together with a cetylpyridinium chloride mouthwash works better than regular fluoride toothpaste alone for reducing dental plaque and gum inflammation (gingivitis). 82 adults with mild to moderate gum disease used the…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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Toothpaste showdown: which paste fights cavities best?
Disease control CompletedThis study tested how well three different toothpastes protect teeth from cavities. Thirty-six healthy adults wore a special dental device for six weeks to measure changes in enamel hardness. The goal was to see which toothpaste best prevents mineral loss and keeps teeth strong.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Mouthwash may keep the sniffles away!
Prevention CompletedThis study tested whether gargling with a mouthwash containing cetylpyridinium chloride and zinc can reduce cold and flu symptoms. 150 healthy adults either brushed their teeth alone or brushed and then gargled with the mouthwash twice daily for 90 days. Researchers tracked how m…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Prevention
Last updated May 22, 2026 13:51 UTC
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Smart toothbrush and coaching cut cavity costs in kids Post-Surgery
Prevention CompletedThis study looked at whether giving children a connected toothbrush, special toothpaste, and behavioral support after cavity surgery could improve brushing habits and lower future dental costs. About 93 kids aged 4-7 who had already been treated for cavities in the operating room…
Sponsor: Colgate Palmolive • Aim: Prevention
Last updated May 18, 2026 12:03 UTC
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Toothpaste showdown: can potassium nitrate beat cavity protection for sensitive teeth?
Symptom relief CompletedThis study tested whether a toothpaste with 5% potassium nitrate can reduce tooth sensitivity better than a regular cavity-protection toothpaste. 80 adults with sensitive teeth used one of the two toothpastes for eight weeks. The researchers measured sensitivity using a gentle to…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 26, 2026 08:49 UTC
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New toothpaste fights bad breath all day, study finds
Symptom relief CompletedThis study tested whether a new toothpaste with stannous fluoride can keep breath fresh longer than regular fluoride toothpaste. 80 adults in Bangkok brushed twice daily for 3 weeks. Researchers measured bad breath 12 hours after brushing. The goal was to see if the new toothpast…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 26, 2026 08:45 UTC
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Toothpaste showdown: hydrogen peroxide vs. fluoride for instant stain removal
Symptom relief CompletedThis study tested whether a toothpaste with hydrogen peroxide removes tooth stains better than a regular fluoride toothpaste after a single brushing. Eighty healthy adults brushed once under supervision, and researchers measured stain removal. The goal was to see if the hydrogen …
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 26, 2026 08:39 UTC
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Gel could soothe pain after gum grafts, small study suggests
Symptom relief CompletedThis study tested whether a special gel made from hyaluronic acid (HA) can help reduce pain and speed up healing after gum graft surgery. Thirty adults aged 18 to 70 who needed a gum graft from the roof of their mouth took part. The gel was applied to the wound, and researchers m…
Phase: NA • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 26, 2026 08:30 UTC
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New whitening system brightens smiles in clinical trial
Symptom relief CompletedThis study tested a new tooth whitening system used at the dentist's office. 180 healthy adults aged 18-70 took part. The goal was to see how well it whitens teeth compared to other whitening systems already available.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 26, 2026 08:30 UTC
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Toothpaste breakthrough: arginine formula takes on tooth sensitivity!
Symptom relief CompletedThis study tested a toothpaste containing 8% arginine to see if it reduces tooth sensitivity better than a standard toothpaste. 80 adults with sensitive teeth used one of the two toothpastes for eight weeks. The goal was to measure relief from pain caused by touch or cold air.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 26, 2026 08:28 UTC
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Toothbrush showdown: which brush beats stains?
Symptom relief CompletedThis study tested how well manual toothbrushes remove tooth stains over 6 weeks. 80 adults with visible stains brushed normally and had their stains measured. The goal was to see which brush works best for cleaner-looking teeth.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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Toothpaste showdown: arginine formula takes on sensitive teeth
Symptom relief CompletedThis study tested whether a toothpaste containing 8% arginine is better at reducing tooth sensitivity than a standard toothpaste. 84 adults with sensitive teeth used one of the two toothpastes for 8 weeks. The goal was to see if the arginine toothpaste provided more relief from p…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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Whitening showdown: Colgate's peroxide paste beats plain toothpaste
Symptom relief CompletedThis study tested whether a Colgate toothpaste containing 5% hydrogen peroxide and fluoride whitens teeth better than a similar toothpaste without peroxide. Eighty adults brushed with one of the two toothpastes for one week. Dentists measured tooth color changes using a shade gui…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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New toothpaste aims to soothe sensitive teeth in just 8 weeks
Symptom relief CompletedThis study tested whether a special toothpaste with 8% arginine can reduce tooth sensitivity better than a regular toothpaste. 95 adults with sensitive teeth used the toothpaste for 8 weeks. Researchers measured sensitivity using a gentle touch and a puff of cold air.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Toothpaste showdown: which one soothes sensitive teeth fastest?
Symptom relief CompletedThis study tested whether a toothpaste with stannous fluoride can reduce tooth sensitivity better than a potassium-based toothpaste or a regular fluoride toothpaste. 123 adults with sensitive teeth used one of the three toothpastes for 7 days. The goal was to see which toothpaste…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated May 20, 2026 11:53 UTC
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Can a quick quiz boost your tooth knowledge? study finds out.
Knowledge-focused CompletedThis study tested whether an online oral health quiz called Know Your OQ helps people learn more about taking care of their teeth and gums. 176 adults took the quiz and gave feedback on how easy it was to understand and use. The goal was to see if the quiz is a helpful tool, not …
Sponsor: Colgate Palmolive • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC