Whitening toothpaste with hydrogen peroxide tested for stain removal
NCT ID NCT07276672
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a toothpaste containing hydrogen peroxide removes tooth stains better than a regular fluoride toothpaste after just one brushing. 80 healthy adults brushed once under supervision, and their tooth stains were measured. The goal is to see if the hydrogen peroxide toothpaste works faster for immediate whitening.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hydrogen peroxide toothpaste
- What this could lead to
- If it works, this could offer a more effective option for removing tooth stains with regular brushing.
- What could go wrong
- This is a small, completed trial focused on immediate stain removal after a single brushing, so long-term effects or benefits are not tested. Results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
-
80 people
The number who actually took part.
- Started
-
Nov 2025
- Finished
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Nov 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Signed Informed Consent Form; * Male and female subjects, aged 18-70, inclusive; * Good general health and good oral health based on the opinion of the study investigator; - Presence of permanent natural anterior teeth (no veneers/crowns/restorations that may interfere with this study scoring procedures); * A minimum composite mean of ≥ 1.5 determined by the Mod. Lobene Tooth Stain Index; * Available for the duration of the study; * Clinical evidence of a tendency to form extrinsic stains on anterior teeth Exclusion Criteria: * Presence of orthodontic appliances/retainers involving scorable teeth; * Presence of partial removable/fixed dentures and/or restorations involving scorable teeth; 3. Tumor(s) of the soft or hard tissues of the oral cavity; * Obvious signs of periodontal disease rampant caries, or any condition that the dental examiner considers exclusionary from the study; * Five or more carious lesions requiring immediate care; * Use of antibiotics, stain-inducing medications, and/or on any prescription that might interfere with the study outcome; * Concurrent participation in another clinical study; * Self-reported pregnancy and/or lactating women; * Have used professional whitening product within one (1) year or had a dental prophylaxis (professional dental cleaning) within thirty (30) days - prior to the start of the study * History of allergies or sensitivity to tooth whitening products, hydrogen peroxide, personal care consumer products, or their ingredients; * History of alcohol and/or drug abuse.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Spa Dental
Santo Domingo, 10148, Dominican Republic
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