Colgate-Palmolive

This Phase 3 trial tests whether a multi-component oral hygiene regimen, including specific mouthwashes and toothpaste, improves outcomes in adults with stage II periodontitis undergoing non-surgical periodontal treatment. Participants will use either an active regimen or a place…

This study will test if a toothpaste with stannous fluoride can reduce bacteria on teeth, tongue, cheeks, and gums better than a regular toothpaste. About 100 adults with plaque and gingivitis will brush with one of the two toothpastes. The goal is to see which one controls bacte…

This Phase 3 trial will test whether a toothpaste containing chitosan, a natural substance, can reduce plaque, gingivitis, and gum bleeding better than a standard fluoride toothpaste. About 90 adults aged 18-70 with good general health will brush with either the chitosan toothpas…

Researchers are testing a device called BlueCheck to see if it can reliably find early enamel lesions and track how they change over 12 weeks. Participants aged 13 and older with active enamel lesions but no cavities needing immediate fillings receive high-fluoride toothpaste and…

This trial tests whether training nursing home staff to provide better oral hygiene can reduce pneumonia in residents aged 60 and older. Participants will use special toothpastes and mouthwashes, including stannous fluoride and chlorhexidine options. The study measures how many r…

This study looks at how gum inflammation and the bacteria in your mouth interact with your body's immune system. Twenty healthy adults will use a special toothpaste and then stop brushing for a period to see how inflammation and bacteria change. The goal is to better understand t…

This study tests how well three different toothpastes repair early tooth damage (enamel lesions) in 30 healthy adults aged 18-70. Participants wear a removable mouth device with human enamel pieces for 14 days per toothpaste, with breaks in between. Researchers measure mineral ga…