Centre Hospitalier Universitaire, Amiens

This study tested two different antibiotic combinations to treat a rare lung infection caused by M. xenopi bacteria. 92 adults received either clarithromycin or moxifloxacin along with two other antibiotics. The main goal was to see which combination cleared the bacteria from spu…

This study tested a new method to guide how quickly heart surgery patients are taken off norepinephrine, a drug that raises blood pressure. The method uses a measure called dynamic arterial compliance to decide when to reduce the drug. 130 adults who had heart surgery and develop…

This study looked at 62 patients who had a hip replacement revision using a special cup (dual-mobility) cemented into a metal ring. The goal was to see if this method prevents the implant from loosening or dislocating. Patients were followed for at least 5 years after surgery.

This study tested whether sleeve gastrectomy (a weight-loss surgery) improves walking ability in people with severe obesity. 99 adults with a BMI over 35 or 40 took a 6-minute walk test before surgery and again 6 months after. Researchers also measured quality of life using quest…

This study tested a drug called sevelamer carbonate in 98 people with chronic kidney disease (stages 3b or 4) who were not on dialysis. The goal was to see if the drug could lower high levels of FGF-23, a protein linked to mineral imbalances, by reducing phosphate absorption from…

This study tested a new treatment plan for people with a severe type of brain cancer called glioblastoma who are too sick for standard radiation. Doctors gave a combination of two drugs, bevacizumab and temozolomide, first to shrink the tumor and improve symptoms. The goal was to…

This Phase 3 trial tested whether tetrabenazine (Xenazine) can reduce involuntary movements in people with tardive dyskinesia, a condition caused by long-term use of antipsychotic medications. Fifty-four adults with persistent symptoms were randomly assigned to receive either tet…

This study tested a procedure to close a small pouch in the heart (the left atrial appendage) in people with atrial fibrillation who had a brain bleed and cannot use standard blood thinners. The goal was to see if this could prevent future strokes without causing another bleed. R…

This study tested two different combinations of immunosuppressant drugs in 88 adults who received a new kidney. The goal was to see which plan better protects kidney function over the short term. All participants took lifelong anti-rejection medication, so this is about managing …

This study looked at whether using a patient's genetic information to set the starting dose of the anti-rejection drug tacrolimus leads to better drug levels in the blood after a kidney transplant. 280 adults receiving a kidney transplant were randomly assigned to get either a st…

This study tested a powerful treatment plan for people under 70 with primary plasma cell leukemia, a rare and aggressive blood cancer. The approach combined several chemotherapy drugs followed by one or two stem cell transplants (using the patient's own cells or a donor's) and th…

This study tested a new way to guide treatment during major surgery by measuring gases in a patient's breath. The goal was to see if this approach could help doctors give the right amount of fluids and medicines to prevent organ failure after surgery. 350 adults having abdominal,…

This study looked at 43 patients who had one adrenal gland removed to treat primary hyperaldosteronism, a condition where a hormone imbalance causes high blood pressure. Researchers checked blood pressure and medication use 1 month, 1 year, and many years after surgery. They foun…

This study tested the drug thalidomide in people with a rare disease called systemic mastocytosis, where too many mast cells build up in the body. The goal was to see if thalidomide could shrink the disease by cutting off its blood supply. The trial included adults whose disease …

This study looked at whether giving antibiotics after gallbladder removal surgery for mild to moderate gallstone inflammation helps prevent infections. Over 400 adults who had early surgery were followed for 30 days. The goal was to see if antibiotics reduce surgical site or othe…

This study looked at 128 kidney transplant patients with chronic graft dysfunction and anemia. Researchers compared two different hemoglobin levels to see which one better improved quality of life after 6 months and slowed kidney function decline over 24 months. The goal was to f…

This study tested whether using a special filter called Oxiris during heart-lung bypass surgery can reduce inflammation and improve blood flow in small blood vessels. 70 adults having planned heart surgery were included. The filter aims to remove inflammatory substances, potentia…

This study looked at giving a drug called norepinephrine early during major abdominal surgery to prevent low blood pressure. The goal was to see if this approach reduces organ problems and other complications after surgery. 500 adults aged 50 and older at higher risk took part. T…

This study tested whether a green dye called indocyanine green (ICG) works as well as standard contrast dye for seeing bile ducts during gallbladder removal surgery. The trial involved 156 adults with acute gallstone cholecystitis. The goal was to see if ICG could help surgeons a…

This study tested whether a special PET scan using florbetapir can help doctors figure out why some people develop memory and thinking problems after a stroke. The scan looks for amyloid plaques, a hallmark of Alzheimer's disease. Researchers studied 92 adults aged 40 to 80 who h…

This study tested whether a new MRI technique using artificial intelligence (deep learning) can accurately measure heart function while patients breathe normally, instead of holding their breath. The standard method requires repeated breath-holds, which can be hard for people wit…

This study tested whether a thermal camera could detect intestinal inflammation in 43 children with Crohn disease. The camera measures heat patterns on the belly, which may reflect underlying inflammation. Researchers compared these readings to standard stool tests and symptom sc…

This study tested whether new deep learning (AI) technology can make prostate MRI scans faster while still finding suspicious nodules. Researchers compared standard MRI sequences with faster, AI-enhanced versions in 34 adults referred for prostate MRI. The goal was to see if the …

This study tested whether an ultra-low-dose CT scan, combined with a deep-learning AI reconstruction, can accurately detect urinary tract stones. 62 adults with known or suspected kidney stones received both a standard low-dose CT and an additional ultra-low-dose scan (less than …

This study tested a small monitoring device called a microdialysis catheter in 21 people who had rectal cancer surgery. The goal was to see if the device could help doctors quickly spot internal leaks where the bowel was reconnected. Early detection of such leaks could prevent se…

This study tested whether an early, quick PET scan using F-DOPA can help doctors tell the difference between a brain tumor coming back and damage from radiation therapy. Eight patients who already needed a PET scan for their brain metastases took part. The goal was to see if meas…

This study tested whether the Nephrocheck™ device can predict if early acute kidney injury will reverse within 72 hours in patients with septic shock. Researchers enrolled 184 adults in the ICU and measured the device's accuracy. The goal is to help doctors decide who might recov…

This study tested whether a special MRI technique called 4D flow can accurately measure blood pressure in the lungs of people with pulmonary hypertension. 28 patients had both the MRI and the standard invasive catheterization to compare results. If the MRI proves reliable, it cou…

This study tested whether a new ultra-low dose CT scan, using deep learning to improve image quality, can accurately find lung nodules compared to standard low-dose CT. 70 adults getting a chest CT for nodule check-up or follow-up took part. The goal was to see if the new method …

This study tested a new method called CO-rebreathing to measure red blood cell mass in people with polycythemia, a condition where the body makes too many red blood cells. The goal was to see if this simple, non-invasive breath test works as well as the standard radioactive blood…

This study tested a new method using imaging flow cytometry to diagnose platelet disorders and heparin-induced thrombocytopenia (HIT). Researchers compared this technique with standard lab tests in 31 patients. The goal was to see if the new method is as good or better at detecti…

This study tested whether a noninvasive ultrasound done on the belly (transperineal) can accurately measure cervical length in pregnant women, compared to the standard internal ultrasound. The goal is to find a less uncomfortable way to check for risk of early labor. 85 women in …

This study tested a new method for PET scans that tracks breathing to get clearer images of lung tumors. 103 adults with small lung nodules took part. The goal was to see if this technique helps doctors find and measure lung cancer more accurately.

This study tested whether wrapping premature babies in a polyethylene bag during central line placement helps prevent dangerous drops in body temperature. The procedure can take 30 minutes to 2 hours, and opening the incubator causes heat loss. 63 premature infants (32 weeks or l…

This study looked at 363 women with a history of three or more early miscarriages who carry a specific gene mutation (MTHFR C677T). Researchers compared two treatments during pregnancy: aspirin plus folic acid, or the same plus a blood thinner (enoxaparin). The goal was to see wh…

This study tested whether taking vitamin C before and after planned upper limb surgery could prevent a chronic pain condition called Complex Regional Pain Syndrome (CRPS) type 1. About 995 adults took part. The goal was to see if vitamin C, an antioxidant, reduces the number of p…

This study tested whether relaxation therapy can reduce chronic pain and improve daily life in people with fibromyalgia. Eighty adults with fibromyalgia were randomly assigned to either active relaxation sessions with a therapist or to relax alone in a quiet room (placebo) for 12…

This study compares two ways to relax the abdominal muscles during laparoscopic (keyhole) digestive surgery. One method is a nerve block called TAP block, which numbs the abdominal wall. The other is a standard muscle relaxant drug called curare. The trial involves 60 adults aged…

This study tested whether spinal anesthesia (numbing the lower body) helps doctors turn a breech baby (feet-first) to a head-down position more successfully than standard sedation. 186 pregnant women at 36+ weeks participated. The goal was to increase the chance of a successful v…

This study looked at whether adults with simple appendicitis can safely have their appendix removed and go home within 12 hours, instead of staying overnight in the hospital. 120 patients were enrolled to see if this outpatient approach is feasible. The goal was to reduce hospita…

This study tested three different numbing methods for people having lung surgery (thoracoscopy). 155 adults received either a serratus plane block, a paravertebral block, or both together before surgery. The goal was to see which method reduced pain the most after the operation. …

This study tested a medicine called 3,4-diaminopyridine (FIRDAPSE) in people with severe botulism who needed a breathing machine. The goal was to see if the drug could improve muscle strength and breathing. Only 3 people took part, and researchers measured changes in nerve signal…

This pilot study looked at whether a supervised or distance-supervised brisk walking program could help manage fatigue in breast cancer patients currently on hormone therapy. Seventeen women who had completed chemotherapy and/or radiation took part in a 6-week program, walking tw…

This study looked at whether placing a bridge device during ileostomy surgery helps prevent problems like infections or skin irritation. 166 adults having planned colorectal surgery with an ileostomy took part. The goal was to see if the device reduces complications and makes car…

This study tested whether a gel made from timolol, a drug usually used in eye drops, can help heal chronic leg ulcers caused by poor vein circulation. 42 adults with ulcers that had not healed after at least 24 weeks of standard care were enrolled. For 12 weeks, half received sta…

This study tested two different ways of using a breathing machine during the night to help people with COPD stop relying on the machine. 19 patients in the hospital took part. The goal was to see which method helped them breathe on their own faster and sleep better.

This study tested if giving the antibiotic teicoplanin as a shot under the skin is safe for treating bone and joint infections. Thirty adults with infections that were resistant to other antibiotics took part. The main goal was to see how well the shot was tolerated at the inject…

This study compared two numbing medicines (levobupivacaine and ropivacaine) given as a spinal injection for leg surgery. 50 adults took part to see which medicine numbed the leg longer and affected movement less. The goal was to find the better option for pain control during surg…

This study tested whether a common weight-loss surgery (laparoscopic sleeve gastrectomy) could be safely performed as a day-case procedure, meaning patients go home the same day. Thirty adults with obesity were enrolled, and researchers tracked how many needed an unexpected overn…

This study looked at health insurance records of over 75,000 people with cirrhosis in France to see if doctors follow guidelines for early liver cancer screening. The goal was to find out how often screening is done correctly and what factors might lead to missed or delayed diagn…

This study looked at whether a substance called M-CSF in the blood can indicate bone damage in people with multiple myeloma. Researchers compared M-CSF levels in 111 participants: those with multiple myeloma, those with a pre-cancer condition called MGUS, and healthy controls. Th…

This study explored whether lab-grown skin models containing a patient's own melanoma cells could predict which drug combinations would work best. Researchers took a small sample of a skin metastasis and used it to create 3D cultures and artificial skin. The goal was to test diff…

This study tested whether the POSOS app, an AI tool, helps emergency doctors detect drug-induced harm (iatrogenesis) in simulated patient cases. 85 doctors were randomly assigned to use the app or not, and their accuracy was measured at 5 and 15 minutes. The goal is to see if suc…

This study looked at whether the common diabetes drug metformin can be used safely in people with kidney failure. Researchers gave increasing doses of metformin to 82 diabetic patients with various stages of kidney disease and measured drug levels in their red blood cells. The go…

This study combined MRI and CT scans from 150 healthy newborns to create a detailed head template. MRI shows soft tissues well, while CT captures bone and fontanelles. The goal is to improve how doctors locate brain activity sources, such as seizures, in infants.

This study tested whether a questionnaire called VQ11 can accurately measure changes in quality of life for people with COPD who start taking a long-acting bronchodilator. Fifty-seven stable COPD patients filled out the VQ11 before and after three months of treatment. The goal wa…

This study reviewed 1251 intrauterine insemination (IUI) cycles at one hospital to see if the type of fertility drug used or the cause of infertility affected pregnancy rates. Participants were women aged 20-44 with normal ovulation and their partners with adequate sperm. The res…

This study compared two drugs used to start labor in pregnant women at full term with an unfavorable cervix. One group received oral misoprostol pills, the other received vaginal dinoprostone gel or insert. Researchers tracked how many women delivered vaginally within 24 hours, a…

This study looked at a thin layer of proteins and sugars that lines blood vessels, called the glycocalyx, in 28 people having heart surgery. The goal was to see if changes in this layer relate to fluid leaking out of blood vessels, which can cause swelling. By measuring glycocaly…

This completed study looked at whether a protein called vasorin in the blood can help predict how severe kidney injury will be in people with septic shock. Researchers took blood samples from 50 intensive care patients on day 0 and day 3. The goal was to see if vasorin levels are…

This study looked at whether measuring procalcitonin (PCT) levels in the blood could help detect infections earlier in people with stage IV non-small cell lung cancer starting chemotherapy. Researchers enrolled 45 patients and took a PCT blood sample before their first chemo sess…

This study looked at whether the constant low-level radiofrequency exposure from medical devices in the NICU affects the brain development of preterm infants. Researchers measured exposure levels over six weeks and tracked sleep patterns, brain oxygen levels, and heart rate in 40…

This study tested a new way to analyze red blood cells in people with anemia using flow imaging and artificial intelligence. Instead of the usual method of spreading blood on a slide and staining it, the researchers used a machine that takes pictures of cells flowing in liquid. T…

This completed study reviewed 37 cases of rare brain tumors (DIA/DIG) in infants treated in French hospitals over 20 years. Researchers analyzed medical records and tumor samples to see why some tumors stay benign while others turn aggressive. The goal is to find clues that could…

This study compared two common positions for digital rectal exams: lying on your side (lateral decubitus) versus lying on your back (supine). Researchers wanted to see which position allows doctors to perform a more complete exam. The study involved 320 men with conditions like c…

This study tested whether a computer program could predict which older patients (over 75) would have unnecessary days in the hospital. Researchers analyzed electronic health records from 102 patients in an acute geriatric unit. The goal was to create an algorithm that flags when …

This study looked at 58 full-term newborns with suspected early-onset sepsis to find early clinical signs that could help doctors tell if a bacterial infection is present. Researchers reviewed medical records from 2013 at a single hospital. The goal was to improve diagnosis and a…

This study looked at whether a substance in the blood called D-dimer can help predict how well people recover after a stroke. Researchers measured D-dimer levels in 102 stroke patients who had received treatment to restore blood flow. They then compared these levels with standard…

This study tracked 883 adults with atrial fibrillation to see how faithfully they took their direct oral anticoagulants (blood thinners). Researchers used pharmacy refill records and questionnaires to measure adherence. The goal is to create a profile of patients at risk of skipp…

This study tested whether the usual method of placing ACL reconstruction tunnels at the center of the natural ligament attachments actually keeps the new ligament taut (isometric) throughout knee motion. Thirty healthy volunteers had their knees scanned with a special 4D scanner …

This study looked at small molecules called microRNA in the blood and in plaques removed from the carotid arteries of 14 adults during surgery. The goal was to find new biomarkers that could help understand or track carotid artery disease. The study did not test any treatment, bu…

This study used MRI to measure blood flow in the eye's main artery in 20 adults with untreated glaucoma and compared it to healthy people. The goal was to understand how blood flow problems might contribute to glaucoma damage. Participants had one MRI scan, and no treatment was g…

This completed study looked at 114 adults with a type of brain bleed called subarachnoid hemorrhage from a ruptured aneurysm. Researchers measured the optic nerve sheath on early CT scans to see if the size could predict whether a patient would survive for 6 months. The goal was …

This study looked at a hospital outbreak of a hard-to-treat bacteria (VIM-producing Enterobacter cloacae) in an intensive care unit during the 2020 COVID-19 pandemic. Researchers reviewed the cases of 14 ICU patients who caught this superbug to understand how the outbreak was man…

This study looked at tiny particles called extracellular vesicles found in urine. Researchers measured these particles in 143 healthy adults and people with chronic kidney disease to find normal and abnormal levels. The goal was to learn more about kidney disease, not to test a t…

This study tested a device called ANI that measures pain during weight-loss surgery in 15 adults. The goal was to see if using the monitor helps doctors give less morphine. The study is complete and focused on improving pain control during surgery.

This study looked at whether a special nurse consultation can help people with rheumatoid arthritis become more independent and safe when managing their injectable biotherapy. Many patients don't know the warning signs of side effects and often delay seeking help. The study enrol…

This study looked at 75 older adults with suspected normal pressure hydrocephalus, a condition that can cause a reversible form of dementia. Researchers used a combination of fluid infusion tests and special MRI scans to better understand how brain fluid and pressure interact. Th…

This study looked at 21 adults with COVID-19 who had neurological symptoms like loss of smell, headache, or memory problems. Researchers used MRI scans to find brain changes linked to the virus. The goal was to better understand how COVID-19 can affect the brain, not to test a tr…

This study looked at whether using strong steroid creams for 6 months to treat bullous pemphigoid (a blistering skin condition) causes bone loss. 47 adults had their bone density measured at the start and end of treatment. The goal was to see if these creams increase the risk of …

This study looked at how well people with bipolar I and bipolar II disorder recognize facial emotions compared to healthy individuals. Ten participants completed a facial emotion recognition test and questionnaires. The goal was to see if there are differences between the two bip…

This study tested whether a special heart ultrasound technique can predict serious heart problems in people recovering from lung surgery. 191 adults having planned lung surgery received ultrasounds before, two days after, and 15 days after their operation. Researchers tracked hea…

This study looked at 107 women having a first-time cervical procedure (LEEP) for abnormal cells. Researchers compared how local anesthesia (cervical block) versus general or spinal anesthesia affected the size of the removed tissue. The goal was to see if the anesthesia method in…

This study looked back at the records of 652 patients who were seen in the emergency department of a French hospital and then referred to a special addiction liaison team. The goal was to understand the social and medical backgrounds of these patients. The findings could help hos…

This study followed 104 people with venous leg ulcers to see which factors might predict healing within 24 weeks. Researchers checked medical history, mental health, and social background. The goal was to find patterns that could help doctors offer better care.

This study looked at how Doose syndrome, a rare form of epilepsy, affects children's ability to learn and develop. Researchers surveyed parents of 9 children diagnosed between ages 1 and 6. The goal was to understand the disease's impact on learning and track how epilepsy changes…

This study looked at whether reading stories to premature babies in the hospital helps improve the connection between mother and baby. Researchers measured heart and breathing patterns in 27 mother-baby pairs. The goal was to see if reading together creates better rhythmic commun…

This study looked at 201 very premature babies born before 31 weeks to see how often they received blood transfusions that went beyond French guidelines. Researchers found that many transfusions were given even when not recommended, possibly due to the babies' fragile health. The…

This study tested a new 4D MRI technique to create a 3D map of blood flow in the liver. 44 adults who had fasted for 6 hours took part. The goal was to see if this method could accurately measure blood flow through the liver's main vessels. The results could improve how doctors i…

This study tested whether a simple lung ultrasound can accurately detect fluid overload in people on hemodialysis. 46 patients had an ultrasound before their regular dialysis session, and the results were compared to other standard tests. The goal is to help doctors better determ…

This study looked at three ways to help people with rheumatoid arthritis take their methotrexate medication as prescribed: usual doctor visits, text message reminders, or a chat with a pharmacist. The goal was to see which method works best to improve adherence. The study include…

This study looked at 73 patients to see if taking vitamin K antagonists (a type of blood thinner) is linked to more calcium deposits in the aorta. Researchers compared CT scans of people on the drug with those who never took it. The goal is to understand whether these common bloo…

This study tested over 1,000 newborns in the Picardie region of France to see if they were exposed to common pesticides before birth. Researchers measured pesticides in the baby's first stool (meconium) and in the mother's hair, and asked mothers about their exposure. The goal wa…

This completed study looked at how the antibiotics amoxicillin and clavulanic acid get into the infected fluid around the lungs (pleural fluid) in 11 patients with pleural infections. All patients had a chest tube to drain the fluid and received standard antibiotic doses. The goa…

This study followed 37 adults over age 60 with unexplained low platelet counts to see if certain tests could predict immune thrombocytopenic purpura (ITP). Participants had blood tests, bone marrow biopsies, and a short course of the steroid prednisone. The goal was to find which…

This study looked at how accurately patients with alcohol intoxication in the emergency department estimate their own blood alcohol concentration (BAC) compared to a real blood test. Researchers enrolled 34 adults aged 15-64 with a BAC of 60 mg/dL or higher. The goal was to see i…

This study looked at 30 undernourished teens with anorexia, aged 11 to 17, to see how taking oral phosphorus supplements for 6 months changes a hormone called FGF23, which helps control phosphate and vitamin D levels. The goal was to understand the link between phosphorus intake …

This study examined 41 patients treated for non-tuberculous mycobacteria (NTM) infections, comparing those with and without cancer. The goal was to count side effects from NTM treatment in each group to understand why cancer patients often stop therapy. Researchers hope this will…

This study looked at 65 pregnant women at risk of preterm birth to see if giving them a booklet along with a doctor's explanation helped lower their anxiety more than just talking with the doctor. The women were split into two groups: one got only oral information, the other got …

This study looked at whether people with Parkinson's disease have higher levels of perfectionism, and how that relates to depression and anxiety. Researchers compared 59 participants with Parkinson's to a control group. The goal was to better understand the emotional challenges o…

This study looked at how often thinking, memory, and behavior problems happen after a stroke. Researchers tested over 1,600 people, including stroke patients and healthy volunteers, using a new French-language test battery. The goal was to better understand and diagnose these iss…

This study looked at how deep brain stimulation (DBS) changes brain activity in people with Parkinson's disease while they performed driving and impulse-control tasks. Fifteen participants had their brain blood flow measured with a special light-based imaging technique, both with…

This study looked at 141 people who had pancreatic surgery (pancreaticoduodenectomy). It compared removing surgical drains early (4 days after surgery) versus the usual time (10-15 days). The goal was to see if early removal reduces surgical site infections. Only patients without…

This study looked at how much lidocaine and ropivacaine stay in the blood when both are used for pain control during major abdominal surgery. It involved 51 adults having open abdominal surgery. The goal was to understand if combining these drugs is safe and how their levels chan…

This study reviewed medical records of 966 children diagnosed with Crohn's disease or ulcerative colitis between 1988 and 2011. Researchers looked at how often children needed surgery and how treatments like immunosuppressants and anti-TNF drugs were used over time. The goal was …

This study looked at a specific type of brain activity in very premature infants (born between 26 and 32 weeks). Researchers used EEG to find where this activity happens in the brain. The goal was to learn more about how the brain develops early on, not to test a treatment. 28 he…

This study looked at healthy blood donors to see if certain antibodies (called antiphospholipid antibodies) are linked to heart disease risk factors like high cholesterol or inflammation. Researchers compared people with and without these antibodies to better understand their rol…

This study looked at 90 adults having scheduled heart surgery to see if two types of ultrasound—one on the chest and one down the throat—give the same measurement of right heart function. The goal was to find out if doctors can use either method interchangeably during surgery. No…

This study looked at 90 people who had sleeve gastrectomy surgery for obesity but did not lose enough weight. Researchers measured the size of the remaining stomach two years after surgery to see if a larger leftover stomach was linked to failure. The goal was to find a way to de…

This study looked at how a new liquid form of midazolam (a sedative) is processed in the bodies of 37 children aged 6 months to 17 years before surgery. Researchers measured drug levels in the blood to understand how age affects dosing. The goal was to find the right dose for eac…

This study examined whether the standard dose of isoniazid, a key tuberculosis drug, is right for all adults. Researchers measured drug levels in 112 patients to see if some were getting too much or too little. The goal was to understand how individual differences in drug process…

This study tested whether a lung ultrasound can help doctors give the right amount of fluids during surgery. 200 adults having various surgeries were monitored. The goal was to see if the ultrasound could detect early fluid overload as well as standard methods. The findings could…

This study looked at whether a formal medication review at hospital discharge helps reduce the number of potentially harmful drugs prescribed to older adults. Researchers compared two groups of patients aged 75 and older: one group received a standardized medication check, while …

This study looked at 633 women in France who were exposed to pesticides and undergoing IVF. Researchers compared women with a high number of eggs showing a certain abnormality (CLCG) to those with few such eggs. The goal was to see if pesticide exposure was linked to lower IVF su…

This study looked at whether levels of cell free DNA (tiny DNA fragments) in blood and fluid around eggs are higher in women with endometriosis who are doing IVF. Researchers compared 114 women with and without endometriosis to see if these DNA levels relate to egg quality and pr…

This study looked at whether a motivational interview with a doctor helps people with chronic diseases stick to a physical activity program. 114 adults from Amiens took part. The goal was to see if this simple talk could improve how much they exercise and their quality of life.

This study looked at 400 ICU patients receiving beta-lactam antibiotics to see how often these drugs cause neurological problems like confusion or agitation. Researchers measured antibiotic levels in the blood and checked patients' brain function regularly. The goal was to find s…

This study looked at whether measuring the electrical activity of the uterus (called an electrohysterogram, or EHG) can help doctors spot the risk of preterm birth earlier. Researchers monitored 100 pregnant women who were hospitalized for threatened premature delivery. The goal …

This study checked for the HHV6 virus in the skin and blood of 37 adults with blood cancers who developed a rash. The goal was to see how often the virus is present and whether it might be causing the rash. If a link is found, it could help doctors diagnose and treat these rashes…

This study looked at medical records of 128 people treated for brain gliomas at a French hospital between 2008 and 2020. Researchers compared the genetic makeup, MRI scans, and outcomes of children (0-14 years) with those of adolescents and young adults (15-25 years). The goal wa…

This study looked at how repetitive negative thinking, called rumination, affects the emotional and mental health of people with fibromyalgia. Researchers measured rumination and depression levels in 107 adults with fibromyalgia using questionnaires. The goal was to better unders…

This study aims to better understand how facial muscles work during expressions like smiling. Researchers will use MRI scans and motion capture technology to measure both the surface skin movements and the deeper muscle movements. The goal is to create a computer model that helps…

This study looked back at medical records of 18 intensive care patients who received hydroxocobalamin (a form of vitamin B12) for severe vasodilatory shock, a condition where blood vessels widen too much and blood pressure drops dangerously. The goal was to see if the treatment c…

This study tested whether using a video to measure how quickly skin color returns after pressure (capillary refill time) is more reliable than the usual visual method. Researchers studied 59 adults in the intensive care unit. The goal was to see if the video method gives more con…

This study looked at whether using ultrasound to guide arterial catheter placement in intensive care patients improves success on the first try and reduces complications. Researchers enrolled 288 adults in the ICU who needed an arterial line. The goal was to see if ultrasound mak…

This study looked at what happens to mothers and their newborns in the first month after going home from the hospital earlier than usual. It included 177 mothers and babies who were sent home after a short hospital stay. The goal was to see if early discharge leads to any health …

This study tested a new way to decide when to give blood transfusions after heart surgery. Instead of using a fixed hemoglobin level, doctors used a measure of oxygen in the blood (ScvO2) to guide transfusions. The goal was to see if this approach could reduce unnecessary transfu…

This study tested a new MRI method called diffusion tractography to better measure how badly the anterior cruciate ligament (ACL) in the knee is torn. Researchers enrolled 30 adults who had a knee MRI after an injury. The goal was to see if this technique could give a more precis…

This study explored whether infection with parvovirus might trigger Graves' disease, an autoimmune condition affecting the thyroid. Researchers compared 52 participants: those recently diagnosed with Graves' disease and a control group with other thyroid issues. The goal was to s…

This study tested whether drones can safely transport blood samples between hospitals without damaging them. Thirty adult volunteers provided blood samples that were shipped by drone and by ground transport, then compared for temperature, timing, and physical condition. The goal …

This study tested if a system that ranks emergency surgeries by urgency leads to better results. Researchers tracked 756 adults who had non-cardiac emergency surgery. They wanted to see if delays beyond the recommended time for each urgency level increased complications or deaths…

This study looked at whether a special MRI scan (flow MRI) can predict if surgery will help people with normal pressure hydrocephalus, a condition where fluid builds up in the brain. Currently, doctors use a spinal tap to make this prediction. The study enrolled 30 adults and mea…

This study looked at how a type of hands-on therapy (specific back mobilizations) affects muscle activity in the back. 156 healthy adults took part. The goal was to understand the therapy's effects on muscle control, separate from placebo or natural changes.

This study looked at whether patients follow the advice they get when leaving the emergency room. Researchers called 242 adults a week after their ER visit to check if they followed discharge orders. The goal was to understand compliance, not to test a new treatment.

This study looked at whether a substance called β-D-glucan in the blood can help doctors diagnose and monitor fungal infections in the abdomen (peritonitis). Researchers measured daily levels in 70 intensive care patients with and without yeast infections. The goal was to see if …

This study looked at whether the age at which a woman had cervical conization (surgery to remove precancerous cells) affects the length of her cervix during a later pregnancy. A shorter cervix can increase the risk of early delivery. Researchers measured cervix length in pregnant…

This study looked at how often thyroid problems (specifically an underactive thyroid) occur in people with HIV. Researchers reviewed medical records of 154 HIV-positive adults who were treated at a French hospital between 2001 and 2012. The goal was to get a clearer picture of th…

This study looked at how the liver's blood supply changes when healthy people receive extra fluids through an IV. Researchers used MRI to measure blood flow in the liver's main vessels before and after giving 500 ml of saline. The goal was to understand the liver's natural 'buffe…

This study looked at how babies' brains become specialized for language, comparing preterm and full-term newborns. Researchers used EEG and NIRS to measure brain activity while babies heard sounds. The goal was to understand when and where language dominance develops, and how a p…

This study looked at whether a mathematical formula can accurately measure bioavailable testosterone, instead of using a special lab test called radioimmunoassay (RIA). The researchers wanted to see if the two methods give similar results. 270 men and women aged 18 to 90 took par…

This study looked back at 210 patients with aortitis (inflammation of the main artery) or retroperitoneal fibrosis (scar tissue in the abdomen) to find better ways to diagnose these conditions. The goal is to help doctors tell different types apart more accurately, which could le…

This study looked at whether using ultrasound to guide a tracheostomy (a breathing tube placed in the neck) in the ICU is safe and practical. Researchers tracked complications like bleeding, tube misplacement, or injury in 40 adult patients. The goal was to see if this approach c…

This study tested the safety and effectiveness of a once-daily form of metformin (metformin XR) in 12 adults with type 2 diabetes and mild to moderate chronic kidney disease. Researchers measured blood sugar levels continuously and checked kidney and lactate levels over 12 weeks.…

This study tested whether a small monitoring probe (microdialysis catheter) placed directly into the bone can reliably measure the health of bone flaps used in head and neck reconstruction. 34 adults having surgery with bone from the hip or leg took part. The goal was to see if t…

This study looked at how preterm babies' brains develop the ability to recognize their mother's voice. Researchers measured brain activity in 22 premature infants to see which side of the brain processes voices. The goal was to understand how early sound exposure affects brain de…

This study looked at how often sleep apnea occurs in adults with type 1 diabetes. Researchers monitored 53 participants overnight with sleep tests and continuous blood sugar tracking. The goal was to find out how many have sleep apnea and whether it affects blood sugar control.

This study followed 100 people with severe COPD to see if the presence of aspergillus fungus in their sputum is linked to worse quality of life and breathing problems. Participants provided sputum samples and filled out questionnaires at the start, then again by phone after 1 and…

This study looked at 2,500 kidney transplant patients to find out why some develop cancer. The main focus was on the immunosuppressive drugs that prevent organ rejection, which can also raise cancer risk. Researchers tracked patients from four regions in France over 10 years to i…

This study tested a robot-assisted surgical method for cochlear implants in 9 adults with severe hearing loss. The goal was to see if the robot could make the surgery safer and less invasive than the traditional microscope-based approach. Researchers measured surgery time and sur…

This study looked at 97 men with type 2 diabetes to see if a non-invasive skin test (AGE Reader) could detect high levels of AGEs, which are linked to erectile dysfunction. The goal was to find a simple way to screen for sexual health problems and improve overall diabetes care. T…

This study looked at whether thinning of the retina (the back part of the eye) can be a sign of Alzheimer's disease. Researchers compared eye scans from 55 people with Alzheimer's, Lewy body disease, and healthy volunteers. The goal was to see if measuring retinal layers could he…

This study looked at whether inducing labor is a safe option for women whose babies are in the breech position (feet or bottom first) at full term. Normally, these women are scheduled for a C-section. The goal was to see if offering labor induction could lower the risks of surger…

This study tested whether using a machine to help patients breathe (non-invasive ventilation) before a throat procedure allows more time without a drop in oxygen levels compared to normal breathing. Fifty adults scheduled for panendoscopy took part. The goal was to find a safer w…

This study looked at how thinking over and over about pain (rumination) affects mood after physical activity in people with fibromyalgia. 47 adults completed surveys about their emotions and pain levels. The goal was to see if rumination makes negative feelings worse after exerci…

This study looked at how often certain gut bacteria (Enterobacteria) are resistant to a powerful group of antibiotics called carbapenems. Researchers tested samples from 287 patients in northwest France to find the rate of these resistant strains. The goal was to understand the p…