Centre Hospitalier Universitaire, Amiens

This study looked at giving a drug called norepinephrine early during major abdominal surgery to prevent low blood pressure and reduce organ damage. About 500 adults aged 50 and older having long or risky abdominal surgery took part. The goal was to see if this approach lowers th…

This study tested a new way to guide treatment during major surgery by measuring gases in a patient's breath. The goal was to see if this approach could prevent organ failure after surgery. 350 adults having abdominal, orthopedic, or vascular surgery took part. Doctors in the exp…

This study tested two different antibiotic combinations to treat a rare lung infection caused by M. xenopi bacteria. 92 adults with symptoms like cough and weight loss took either clarithromycin or moxifloxacin along with two other drugs. The main goal was to see which combinatio…

This study tested whether sleeve gastrectomy (a weight-loss surgery) improves walking and quality of life in 99 adults with severe obesity. Participants had a 6-minute walk test and filled out quality-of-life surveys before surgery and 6 months after. The goal was to see if the s…

This study tested a multi-step treatment plan for 40 patients under 70 with primary plasma cell leukemia, a rare and aggressive blood cancer. The approach included several rounds of different chemotherapy drugs, followed by one or two stem cell transplants (using the patient's ow…

This study tested whether a noninvasive ultrasound done on the belly (transperineal) is as accurate as the standard internal ultrasound for measuring cervical length in pregnant women. The goal is to find a more comfortable way to check for risk of early labor. Researchers measur…

This study tested whether a new type of PET scan using F-DOPA dye can help doctors tell the difference between a brain tumor coming back and damage from radiation treatment. Eight adults with brain metastases who already needed a PET scan took part. The goal was to see if early i…

This study tested a special breathing technique during PET scans to get clearer images of lung nodules. 103 people with small lung spots (under 35 mm) took part. The goal was to see if this method helps doctors spot cancer more accurately by reducing blur from breathing.

This study looked at whether people with simple (non-complicated) appendicitis can have their appendix removed and go home the same day, instead of staying overnight in the hospital. 120 adults took part. The main goal was to see how many patients could leave the hospital within …

This study tested whether a gel containing timolol, a drug usually used in eye drops, could help heal chronic venous leg ulcers. 42 adults with ulcers that had not improved after 4 weeks of standard care received either timolol gel plus wound dressings and compression, or dressin…

This study tested a new method to safely reduce the use of norepinephrine, a drug that raises blood pressure, in 130 adults after heart surgery. The goal was to find the best time to stop the drug without causing harm. Researchers used a measure called dynamic arterial compliance…

This pilot study tested a drug called 3,4-diaminopyridine in people with severe botulism who needed a ventilator to breathe. The goal was to see if the drug could improve muscle strength and breathing. Only 3 people took part, and researchers measured changes in nerve and muscle …

This study looked at whether relaxation therapy can improve the overall well-being of people with fibromyalgia, a condition causing widespread chronic pain. About 80 adults with fibromyalgia took part, receiving either relaxation sessions or a placebo for 12 weeks. The goal was t…

This study looked at 155 adults having chest surgery to find the best way to control pain. Patients received one of three nerve blocks before surgery. The goal was to see which method reduced pain the most after the operation.

This study looked at whether a special MRI scan (flow MRI) can predict if surgery will help people with normal pressure hydrocephalus, a condition where fluid builds up in the brain. Currently, doctors use a spinal tap to make this prediction. The study involved 30 adults and mea…

This study looked at 90 adults who had sleeve gastrectomy surgery for obesity but did not lose enough weight. Researchers measured the remaining stomach volume two years after surgery to see if a larger leftover stomach was linked to failure. The goal was to find a way to predict…

This study looked at healthy blood donors to see if certain antibodies (called antiphospholipid antibodies) are linked to heart disease risk factors. Researchers compared people with and without these antibodies, checking for things like high blood pressure and cholesterol. The g…

This study tested how well a long-acting form of metformin controls blood sugar over 24 hours in people with type 2 diabetes and mild to moderate chronic kidney disease (stages 1-3). Twelve participants took metformin XR once daily while researchers monitored their glucose levels…

This study looked at 320 men to find out if a digital rectal exam works better when the patient lies on their side or on their back. The goal was to see which position lets the doctor check the full rectum more easily. The results help doctors choose the best way to perform this …

This study looked at whether a substance called β-D-glucan in the blood can help doctors diagnose and monitor fungal infections in the abdomen (peritonitis). Researchers measured its levels daily in 70 intensive care patients with fungal peritonitis and compared them to patients …

This study looked at how preterm infants' brains process their mother's voice. Researchers measured brain activity in 22 babies to see which side of the brain handles voice recognition and how the hospital environment affects development. The goal was to learn more about early br…

This study looked at what happens when mothers and their newborns go home earlier than usual after childbirth. Researchers followed 177 mother-newborn pairs for one month after leaving the hospital to see if any complications occurred. The goal was to understand if early discharg…

This study tested whether using a video to measure capillary refill time (how fast skin color returns after pressing it) is more reliable than the usual visual method. Researchers compared results from different doctors and the same doctor at different times in 59 ICU patients. T…

This study looked at how deep brain stimulation (DBS) changes brain activity in people with Parkinson's disease while they performed driving and impulse-control tasks. Researchers used a special light-based imaging technique to measure blood flow in the brain with the stimulator …

This study looked at tiny particles called extracellular vesicles found in urine to see if they can help tell the difference between healthy kidneys and chronic kidney disease. Researchers measured the number of these particles in 143 adults—both healthy volunteers and people wit…

This study looked at how often certain gut bacteria (Enterobacteria) are becoming resistant to a powerful group of antibiotics called carbapenems. Researchers tested samples from 287 patients in northwest France to find and understand these resistant strains. The goal was to meas…

This study aims to objectively measure how facial muscles move during expressions like smiling. Researchers will use MRI scans and motion capture technology to track both internal muscle and external skin movements in 50 healthy adults. The goal is to create a computer model that…

This study looked at how repetitive negative thinking, known as rumination, affects the emotional and mental symptoms of fibromyalgia. Researchers measured rumination and depression levels in 107 adults with fibromyalgia using questionnaires. The goal was to better understand the…

This study tested a monitoring method called microdialysis to see if it could quickly detect dangerous leaks (anastomotic leaks) after rectal cancer surgery. 21 patients who had rectal surgery with a stoma were included. The goal was to find leaks earlier than standard checks, bu…

This study tested whether drones can safely transport blood samples between hospitals without damaging them. Thirty adults donated blood, which was sent by both drone and regular road transport. Researchers checked if the samples arrived in good condition and at the right tempera…

This study looked at 34 people who came to the emergency department with alcohol intoxication. Researchers asked them to guess their blood alcohol concentration (BAC) and then compared it to a real measurement. The goal was to see if showing patients the difference could help the…

This study reviewed medical records of 966 children diagnosed with Crohn's disease or ulcerative colitis between 1988 and 2011. Researchers looked at how often children needed surgery and how treatments like immunosuppressants and anti-TNF drugs were used over time. The goal was …

This study looked at how often people have thinking, memory, or behavior problems six months after a stroke. Researchers tested over 900 healthy adults and 300 stroke survivors using a new French-language test battery. The goal was to better understand and diagnose these issues, …

This study looked at whether a special questionnaire called VQ11 can measure changes in quality of life for people with COPD who start a new long-acting inhaler. Fifty-seven adults with stable COPD (no flare-ups in the past 6 weeks) filled out the questionnaire before and 3 month…

This study looked at 2500 kidney transplant patients in France to find out what factors, especially the type of anti-rejection drugs, increase the risk of developing cancer after transplant. The goal was to understand how to better predict and possibly prevent these cancers. The …

This study looked at whether a protein called vasorin can help predict severe kidney injury and death in people with septic shock. Researchers measured vasorin levels in 50 intensive care patients. The goal was to see if higher vasorin levels are linked to worse outcomes, which c…

This study looked at how a hospital intensive care unit (ICU) managed an outbreak of a hard-to-treat bacteria called VIM-producing Enterobacter cloacae during the COVID-19 pandemic. Researchers reviewed the care of 14 ICU patients who had this bacteria between March and October 2…

This study looked at whether thinning of certain layers in the retina (the back of the eye) could be a sign of Alzheimer's disease. Researchers compared eye scans from 55 people with Alzheimer's, Lewy body disease, and healthy individuals. The goal was to see if these retinal cha…

This study looked at whether babies in the Picardie region of France are exposed to common pesticides before birth. Researchers tested the baby's first stool and the mother's hair for these chemicals, and also asked mothers about their exposure. The goal was to see how pesticide …

This study followed 104 people with venous leg ulcers to find out which factors help them heal within 24 weeks. Researchers looked at medical history, wound size, and even social and emotional factors. The goal was to better understand why some ulcers heal and others do not, with…

This study tested whether the center of the ACL's natural attachment points keeps the ligament the same length as the knee bends. Thirty healthy volunteers had 4D scans to measure changes in distance between these points. The goal was to see if current surgical methods need impro…

This study tested a device called ANI to measure pain during weight-loss surgery in 15 adults with obesity. The goal was to see if using the monitor could reduce the amount of morphine needed during the operation. Results may help improve pain control and reduce side effects from…

This study looked at how a specific type of hands-on therapy (mobilization) on the upper back affects the activity of back muscles in healthy people. 156 volunteers were split into three groups: one received the therapy, one received a placebo-like treatment, and one had no treat…

This study tested whether using a machine to help people breathe before an ENT cancer screening procedure could keep their oxygen levels safe for a longer time. Fifty adults scheduled for panendoscopy under general anesthesia took part. The goal was to see if the machine-assisted…

This study looked at whether the diabetes drug metformin can be used safely in people with type 2 diabetes who also have kidney disease (stages 1 to 5). Researchers measured metformin levels in red blood cells to see if they stayed within a safe range. About 82 patients took part…

This study looked at whether patients follow the instructions they receive when leaving the emergency room. Researchers called 242 adults a week after their ER visit to check. The goal was to understand how well people follow discharge advice, not to test a new treatment.

This study tested whether a recent parvovirus infection might trigger Graves' disease, an autoimmune thyroid condition. Researchers compared 52 participants—half with newly diagnosed Graves' disease and half with other thyroid issues—looking for parvovirus DNA in their blood. The…

This study looked at how two pain medicines—lidocaine given through a vein and ropivacaine given through an epidural—affect each other's levels in the blood during major abdominal surgery. 51 adults having open abdominal surgery took part. The goal was to see if using both togeth…

This study tested a new heart MRI technique that uses deep learning to create clear images while patients breathe normally, instead of holding their breath. It included 54 adults with ischemic heart disease. The goal was to see if this method measures heart function as accurately…

This study looked at how giving a standard amount of fluid through a vein (a fluid challenge) changes blood flow in the liver. 22 healthy volunteers had an MRI before and after receiving 500 ml of salt water. The goal was to see if the liver's blood vessels adjust as expected. Th…