Centre Hospitalier Universitaire, Amiens

This study tests whether adding an inhaled antibiotic (amikacin liposome suspension) to standard treatment helps clear a rare lung infection caused by Mycobacterium xenopi. The infection is difficult to treat and requires long-term medication. About 190 adults with this infection…

This study tests whether using a simple urine test to guide the dose of a water pill (furosemide) can safely and effectively remove excess fluid after heart surgery. About 102 adults having heart surgery with a heart-lung machine will be randomly assigned to either standard care …

This study looks at whether it is safe to stop antibiotics early in people aged 65 and older who are in the hospital for a viral lung infection. Many older patients get antibiotics even when they have a virus, which can cause side effects and lead to antibiotic resistance. The re…

This study compares two antibiotics, clarithromycin and azithromycin, to treat a lung infection called MAC. About 424 adults with MAC lung disease will receive one of the two drugs, along with other standard medications. The goal is to see if azithromycin works just as well but c…

This study compares a new, faster cardiac MRI that uses artificial intelligence to the standard MRI for measuring heart function in people with left ventricular hypertrophy (thickened heart muscle). The goal is to see if the quicker scan gives equally accurate results while being…

This study is testing whether a blood test measuring a protein called p-Tau217 can accurately diagnose Alzheimer's disease. Currently, diagnosis requires a spinal tap to test spinal fluid, which is invasive and uncomfortable. Researchers will compare the blood test results with t…

This study tests whether using special relaxation glasses or a virtual reality headset can reduce anxiety in adults before orthopedic surgery. About 632 participants will be randomly assigned to one of three groups: relaxation glasses, VR hypnosis, or no relaxation tool. Research…

This study tests whether using a virtual reality program (HypnoVR®) can help reduce discomfort for patients in the surgical intensive care unit (ICU) after major heart, chest, or abdominal surgery. About 194 adults will be randomly assigned to either receive virtual reality sessi…

This study looks at bone marrow stem cells from 50 people with Waldenström macroglobulinemia, a rare blood cancer, and compares them to stem cells from healthy volunteers. The goal is to understand how these stem cells interact with cancer cells and contribute to the disease. No …

This study tracks blood sugar levels continuously in 80 women with polycystic ovary syndrome (PCOS) to see how glucose patterns differ across four PCOS subtypes. Researchers aim to identify which subtypes face higher risk for insulin resistance and type 2 diabetes. Participants w…

This study is testing whether a quick finger-prick blood test (CRP point-of-care testing) can predict a serious complication called anastomotic leak after planned colorectal surgery. The goal is to catch leaks earlier, reduce the need for repeated blood draws, and help patients r…

This study looks at patients with a severe condition called mixed cardiogenic-vasoplegic shock, where the heart fails to pump and blood vessels widen too much. Researchers will review medical records from 2,500 adults in French hospitals to learn how common it is, how it's treate…

This study looks at whether a protein called vasorin can help doctors tell the difference between septic shock (caused by infection) and other types of shock. Researchers will measure vasorin levels in 144 intensive care patients with either septic or non-septic shock. If vasorin…

This study is testing whether placing 15 plants in two rooms of a hospital lab can reduce the amount of formaldehyde in the air. Formaldehyde is a chemical used to preserve tissue samples, but it can be harmful to breathe. The researchers will measure formaldehyde levels in the a…

This study is looking for biological markers that can predict if a glioblastoma patient will survive at least 6 months after treatment with the drug bevacizumab. Researchers will use special brain scans to measure certain chemicals in the tumor. The goal is to identify which pati…

This study explores how brain stimulation can improve movement speed in people who have had a stroke. Researchers will first test healthy volunteers to map brain areas linked to reaction time, then apply targeted stimulation to stroke patients. The goal is to develop personalized…

This study looks at a rare liver condition called Porto-Sinusoidal Vascular Disease (PSVD) that causes high blood pressure in the liver's main vein, leading to serious problems like bleeding or fluid buildup. Researchers want to see how well a procedure called TIPS works for thes…

This study looks at how certain immune cells called monocytes might affect how well CART cell therapy works in people with multiple myeloma. Researchers will measure and study monocytes before and after treatment in 25 patients. The goal is to find clues that could help predict w…

This study looks at a protein called annexin A2 on the surface of certain white blood cells (monocytes) in people with antiphospholipid syndrome, a condition that increases the risk of blood clots. Researchers want to see if lower levels of this protein are linked to the disease.…

This study looks at eye problems in people with craniosynostosis, a condition where skull bones fuse too early. Researchers will check for issues like crossed eyes, lazy eye, and pressure inside the head. The goal is to better understand these eye problems to improve care.

This study aims to find genetic changes that cause orofacial clefts (cleft lip/palate) but are missed by standard tests. Researchers will use a new, high-resolution DNA mapping method called optical genome mapping on 26 people with clefts who have no known genetic diagnosis. The …

This study looks at cancer patients who have a blood clot in a vein just under the skin (superficial vein thrombosis). About 15-20% of these clots happen in people with cancer, but there are no clear treatment guidelines. Researchers will observe 1,576 patients to see how differe…

This study looks at how well two different software programs measure heart function in people with septic shock, a life-threatening condition. Researchers will compare measurements from 60 adult patients to see if the tools give consistent results. The goal is to improve how doct…

This study looks at whether using a special co-sleeping crib (co-dodo) helps breastfeeding mothers and their newborns sleep better and bond more closely in the hospital after birth. About 132 mothers and their babies will be randomly assigned to use either a co-dodo crib or a sta…

This study looks for unknown genetic causes of congenital sideroblastic anemias, a group of rare blood disorders where the body can't use iron properly to make red blood cells. Researchers will analyze DNA from 20 people whose genetic cause is still a mystery. The goal is to find…

This study looks at how pesticides and the natural bacteria in the gut and reproductive organs might be linked to infertility in women with endometriosis. Researchers will compare 160 women with and without endometriosis to measure DNA damage and bacterial patterns. The goal is t…