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Which nerve block works best for post-surgery chest pain?

NCT ID NCT04222010

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested three different nerve block techniques to control pain after thoracoscopic (chest) surgery. 155 adults were randomly assigned to receive either a serratus plane block, a paravertebral block, or both together, using the anesthetic ropivacaine. The goal was to find which method provides the best pain relief and could help prevent long-term pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine (a local anesthetic)
What this could lead to
If successful, this study could identify the best nerve block technique to reduce pain after chest surgery, leading to faster recovery and less chronic pain.
What could go wrong
This is a completed Phase 3 trial with 155 participants, so results are fairly reliable. However, individual responses to pain relief vary, and the best technique may still not eliminate pain for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

155 people

The number who actually took part.

Started

Jan 2020

Finished

Feb 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adult patient over18 years old * without guardianship * video-assisted thoracoscopic surgery with 3 trocars * No cons-indications to loco-regional anesthesia (allergy, skin condition) Exclusion Criteria: * patient under 18 years old * patient under guardianship * pregnant * rejection of consent * rejection of loco-regional anesthesia * chronic pain antecedents under morphine medication * pain assessment impossible

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Amiens

    Amiens, 80054, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.