Assistance Publique - Hôpitaux De Paris

This study is testing a drug called obinutuzumab for people with a rare and serious autoimmune disease called cryoglobulinemia vasculitis, where abnormal proteins damage blood vessels. It is specifically for patients whose disease did not improve with or who could not tolerate th…

This study is testing whether a team-based support program helps people who have had a heart attack lower their 'bad' cholesterol more effectively than standard care alone. The program provides extra consultations with nurses, dietitians, and pharmacists over a year. Researchers …

This study aims to find out if a 4-5 week intensive rehabilitation program is a cost-effective way to treat chronic low back pain that keeps people from working. It will compare the program to standard care for 242 adults in France who have been on sick leave for 3 months to 2 ye…

This early-stage trial is testing a new antibody called DT-7012 for people with advanced cutaneous T-cell lymphoma (CTCL), a type of skin cancer, that has come back or hasn't responded to at least two previous treatments. The study aims to find a safe dose and see if the antibody…

This study looks back at the results of a specific surgery for a rare condition where a leg artery gets pinched during activity, causing pain and limiting movement. Researchers reviewed the medical records of 70 patients who had this surgery to see how well it worked. They measur…

This study aims to find out if using two OSIA bone conduction hearing implants is better than using just one for children born with severe ear malformations. It will involve 12 children, aged 7 to 17, who will receive an implant in each ear. Six months after surgery, researchers …

This study is testing three different biologic drugs (adalimumab, ustekinumab, and baricitinib) to see if they can control painful flare-ups of folliculitis decalvans, a rare condition that causes scarring hair loss. It is for adults whose disease has not been controlled by at le…

This study is testing a liquid embolic agent called SQUIDPERI for treating bothersome urinary symptoms caused by an enlarged prostate (BPH). The procedure, called Prostatic Artery Embolization (PAE), blocks blood flow to shrink the prostate. Researchers want to see if using this …

This study is testing a new type of heart procedure called pulsed-field ablation for people with atrial fibrillation (AFib). Researchers want to see if this method causes less permanent scarring in the heart's upper chamber compared to older heat- or cold-based techniques. They w…

This study aims to see how well light therapy works for people with major depression and to find biological clues that predict who will benefit most. It will enroll 173 adults with moderate to severe depression, who will use light therapy daily for four weeks. Researchers will me…

This study aims to see if using a lower dose of a powerful drug called cyclophosphamide after a stem cell transplant is just as effective as the standard higher dose. It will involve 180 adults with blood cancers who are receiving a transplant from a half-matched donor. The main …

This study aims to find out if cancer patients who develop a blood clot in the lung (pulmonary embolism) can be safely treated at home instead of being admitted to the hospital. It will compare the safety and quality of life for over 800 patients randomly assigned to receive care…

This early-stage study is testing a new gene therapy method for Tay-Sachs and Sandhoff disease, two rare and fatal neurological disorders. Researchers will modify patients' blood stem cells in a lab to produce a missing enzyme, then test if these cells can help correct brain cell…

This study is testing whether a combination of three existing drugs (prednisone, azithromycin, and hydroxychloroquine) can slow the progression of a rare, inherited form of lung scarring. It will enroll 30 adults who have this specific genetic condition. The main goal is to see i…

This study is testing whether getting detailed antibiotic sensitivity results in 4-6 hours, instead of the standard 18-24 hours, helps intensive care unit (ICU) doctors choose the best antibiotic for serious bloodstream infections. It will involve 200 adult ICU patients with thes…

This study is testing a smartphone app called EPIDAY that aims to predict the risk of an epileptic seizure. Adults with focal epilepsy will use the app daily to track warning symptoms. The goal is to see if a computer algorithm can use this information to reliably forecast high-r…

This study is testing a new 'one-stop' clinic day for people with Crohn's disease or ulcerative colitis. During a single hospital visit, patients receive blood tests, doctor consultations, education sessions, and other specialized care all together. Researchers want to see if thi…

This study is testing if a two-part gut cleaning method works better than standard care for people in intensive care after a severe pill overdose. It will involve 200 patients who are on a breathing machine. Researchers will compare a standard charcoal treatment against charcoal …

This study is testing a new, much shorter 6-month drug combination for adults with multidrug-resistant tuberculosis (MDR-TB) in France. It will compare the new regimen's success rate to the results from patients who received older, much longer treatments (often 18+ months). The g…

This study looks back at the medical records of about 400 women in France who were treated for advanced cervical cancer. The goal is to see if a simpler radiation method—using just one implant instead of several—is as effective at controlling the cancer and has similar side effec…

This study is testing whether adding aspirin and folic acid (vitamin B9) to standard steroid treatment can help people recover from sudden, unexplained hearing loss. Researchers believe poor blood flow in the inner ear might cause the condition, and these medications may improve …

This study is testing whether a medication called tocilizumab can help people with a chronic, painful form of calcium crystal arthritis (CPPD) that hasn't improved with usual treatments. About 80 adults in France will receive monthly infusions of either tocilizumab or a placebo f…

This study tests if giving the drug brentuximab vedotin as a preventive treatment after a stem cell transplant can stop an aggressive type of skin cancer (CTCL) from returning. It will involve 84 adults whose cancer had responded to prior treatments but is at high risk of relapse…

This study is testing whether adding daily fiber-rich snacks to standard hospital care helps people going through alcohol withdrawal. Researchers want to see if the fiber improves gut health, reduces cravings and anxiety, and supports liver function. About 138 adults with alcohol…

This study aims to find a better way to prevent disease flare-ups in people with two rare autoimmune conditions (GPA and MPA). It will compare two approaches: giving a treatment called rituximab as soon as a specific blood marker rises, versus the current standard of just monitor…

This study is testing if adding the drug Anakinra to standard hospital care helps children with a sudden, severe heart inflammation called acute myocarditis. It will involve 110 children in intensive care units, comparing Anakinra to a placebo. The main goal is to see if the drug…

This study is testing a new combination of three drugs to control multiple myeloma that has returned or stopped responding to standard treatments. It will involve about 70 adults whose cancer has progressed despite prior therapy, including specific drugs like lenalidomide. The ma…

This study is testing whether a fecal microbiota transplant (FMT) can help control primary sclerosing cholangitis (PSC), a rare and serious liver disease often linked with inflammatory bowel disease (IBD). Researchers will compare FMT capsules to placebo capsules in 72 patients w…

This study compares starting treatment with two oral medications versus one medication for people newly diagnosed with pulmonary arterial hypertension (PAH) who also have at least two other heart-related conditions like high blood pressure or diabetes. It aims to find the safest …

This study is testing whether adding a sound feedback technique to standard early therapy can help people who have just experienced a traumatic event. The technique, called movement sonification, uses wristbands to turn a person's movements into sound, aiming to help them feel mo…

This study is testing whether adding a steroid pill (corticosteroid) to standard antibiotic treatment helps adults recover better from a severe joint infection called septic arthritis. The goal is to see if the steroid reduces long-term joint damage and pain by calming harmful in…

This study aims to find the best way to treat people with rectal cancer that has also spread to the liver. It will follow 550 patients who first receive a strong chemotherapy regimen called FOLFIRINOX. The main goal is to see how many patients can later have successful surgery to…

This study is testing if a drug called secukinumab can help control severe Takayasu arteritis, a rare disease that causes dangerous inflammation in the body's largest blood vessels. It will involve 52 patients with active, severe disease to see if the drug can achieve remission a…

This study aims to find the right dose of the drug sildenafil (often used for lung pressure) when given alongside standard cooling therapy to newborns with brain injury from oxygen deprivation at birth. It will enroll 24 full-term babies to measure how their bodies process the dr…

This large international trial aims to find better, personalized treatments for sepsis, a life-threatening response to infection. It will enroll 2,000 children and adults to test multiple treatments at once, matching them to a patient's specific biological traits. The goal is to …

This study aims to find out if the steroid prednisolone is an effective first treatment for a scarring lung disease called fibrotic hypersensitivity pneumonitis. It will compare the steroid against a placebo in 120 participants to see which one better slows the decline in lung fu…

This study is testing if using data from a body-worn sensor (a smartwatch-like device) can help doctors better adjust Parkinson's medication for patients who experience motor fluctuations. The goal is to reduce the amount of time patients spend in the 'off' state, where symptoms …

This study is testing a new smartphone app designed to measure how quickly color returns to a pressed fingertip, a sign of blood flow called capillary refill time. Doctors currently do this by eye, which can vary between observers. The research will involve 60 adult patients in i…

This study aims to develop better methods for detecting ADHD in preschool children aged 3-6. Researchers will compare 30 children with ADHD symptoms to 30 typically developing children using eye-tracking, balance tests, and questionnaires. The goal is to identify early biomarkers…

This study is testing whether a personalized computer model, called a 'digital twin,' can predict which patients with high blood pressure will respond well to different treatments. Researchers will create these models using patient data and see if they accurately identify who ben…

This study is testing whether a simple, non-invasive liver scan can help doctors diagnose acute heart failure more quickly in emergency room patients who arrive with sudden shortness of breath. Researchers will use a device called Fibroscan® on 100 patients to see if liver stiffn…

This study aims to develop better tools for diagnosing the cause of high male hormone levels in women, a condition called hyperandrogenism. Researchers will use artificial intelligence (AI) to analyze detailed blood test results from 800 women aged 16-45 who have this condition. …

This study aims to develop new blood tests that can predict which patients with early-stage liver scarring (cirrhosis) are at highest risk of developing liver failure or liver cancer. Researchers will analyze tiny particles in the blood called extracellular vesicles, along with o…

This study aims to compare the costs and benefits of a new non-invasive prenatal test to current methods for detecting inherited genetic diseases. Researchers will enroll 300 couples at risk of passing on severe genetic conditions to their unborn child. They will analyze whether …

This study aims to test a new, objective method for programming cochlear implants in young children (aged 0-7 years). The goal is to find a more reliable way to set the comfortable volume levels on the hearing device, which can be hard to determine in young kids. Researchers hope…

This study aims to find better ways to diagnose tricky bone and joint diseases. Researchers will test new lab techniques on fluid and tissue samples from 50 patients to see if they can identify clearer disease signatures. The goal is to help doctors classify patients more accurat…

This study aims to see if a new type of PET scan using a tracer called 82-Rb can accurately tell how aggressive a kidney cancer tumor is before a patient has surgery. Researchers will scan 50 patients with kidney cancer and compare the scan results to the final tumor analysis aft…

This study is testing a new, rapid diagnostic device to detect Candida auris, a drug-resistant fungus that can cause serious infections in hospitals. The test gives results in about 15 minutes and will be compared to the standard lab method. The goal is to see if this faster test…

This study aims to find out if common, non-invasive jaundice screening devices work accurately for newborns with all skin tones. It will enroll 510 newborns and compare the quick skin meter readings with results from blood tests. The goal is to ensure all babies, regardless of sk…

This study aims to see if an ultrasound scan of nerves can help doctors tell the difference between inherited and non-inherited forms of a rare sensory nerve disorder. Researchers will look back at data from about 50 patients who have already had this type of ultrasound as part o…

This study aims to develop and test a new software tool that uses artificial intelligence to create 3D models of a patient's bile ducts from their existing MRI and CT scans. The goal is to give doctors a clearer, three-dimensional 'map' to guide them during a complex procedure ca…

This study aims to spot a rare, serious genetic disorder that can look like common PCOS. Researchers will compare 25 women with a known genetic insulin disorder to 50 women with typical PCOS. They will measure blood sugar, hormones, and body fat to find key differences for earlie…

This study aims to see if artificial intelligence (AI) can better analyze CT scans to determine how advanced a colon cancer is before surgery. It will use existing scans and records from about 1000 patients to train and test the AI models. The goal is to provide doctors with a mo…

This study is testing if special 'active' sports shoes, designed to make walking easier, can help people with severe COPD. Researchers will have 75 participants walk in their usual shoes and in the special shoes to see if they can walk farther and feel less breathless. The goal i…

This study is testing a new, comprehensive treatment plan for sudden, severe low back pain in emergency departments. It combines standard pain medication with advice on staying active, psychological support, and education for both doctors and patients. The goal is to see if this …

This study aims to understand how an artificial urinary sphincter implant affects women's sexual function. Researchers will follow 30 women who have received the implant for urinary incontinence, checking in at 6 and 12 months after surgery. The goal is to see if sexual quality o…

This study is testing whether a portable, non-drug device called actiTENS mini can help reduce chronic pelvic pain in women with endometriosis. It will involve 208 women across 27 centers in France. Participants will use the device daily for several months, comparing different st…

This study is testing whether specially adapted shoes can improve walking for people who have had a stroke. It will involve 58 stroke survivors who have difficulty walking due to foot stiffness and dragging. Researchers will measure if wearing these shoes for 30 days helps people…

This study aims to create and test a self-rehabilitation program for people living with long-term effects of a stroke. The program is designed with patient input and focuses on practicing everyday tasks at home. Researchers will compare the program to usual care to see if it help…

This study compares two different materials used in multifocal lens implants during cataract surgery. Researchers want to see if one type provides better contrast sensitivity (the ability to see details in low light) than the other. Each patient will have one type of lens implant…

This study aims to test a new educational workshop designed to help people with chronic inflammatory rheumatic diseases (like rheumatoid arthritis) feel better about their bodies and themselves. The program will teach skills to improve self-image and self-esteem. Researchers will…

This study is testing whether an inhaled painkiller called methoxyflurane works as well as morphine for severe chest pain during a heart attack. It will involve 700 adults experiencing a major heart attack who are being transported by ambulance. The goal is to find a safer, easie…

This study is testing if a simple, active distraction can help reduce pain and fear when young children get a blood draw or IV. Researchers will have children aged 1 to 3 years shake a maraca with their free arm during the procedure to see if it helps them feel less pain and need…

This study is testing if having adults with sickle cell anemia lie on their stomachs while awake helps them breathe better during a severe lung complication called acute chest syndrome. Researchers want to see if this simple positioning improves oxygen levels and reduces breathin…

This study aims to find out if a newer, lighter carbon-fiber ankle brace helps children with cerebral palsy move better than their usual plastic brace. Researchers will compare how well 38 children, aged 8 to 15, can walk, run, and jump while wearing each type of brace over sever…

This study is testing an education and support program designed to help the family members and friends who care for people with multiple myeloma, a type of blood cancer. It aims to see if teaching caregivers about the disease and coping skills improves their own stress levels and…

This study aims to see if restoring a gentle flow of air through the nose can help patients with a tracheostomy who are on a ventilator feel less short of breath. It will compare three simple, drug-free methods: continuous nasal airflow, nasal sprays, and airflow directed at the …

This study looks back at medical records to see how well two antiviral drugs, nirmatrelvir/ritonavir (Paxlovid) and remdesivir (Veklury), worked for immunocompromised adults hospitalized with COVID-19 in France. Researchers will analyze data from about 300 patients who were treat…

This study aims to understand why glioblastoma, a severe brain cancer, is more common and aggressive in men. Researchers will analyze tumor and blood samples from 40 newly diagnosed patients to see if male hormones (androgens) influence the tumor's environment and the body's immu…

This study aims to see if testing hospital wastewater can reliably show which antibiotic-resistant bacteria are present among patients, offering a simpler alternative to individual patient swabs. Researchers will compare bacteria and resistance genes found in wastewater from a sp…

This study aims to improve IVF success rates by using artificial intelligence (AI) to analyze time-lapse videos of developing embryos. Researchers will look back at data from 1,500 couples to find patterns in how embryos grow and move that predict which ones are most likely to im…

This study aims to understand why some people with a rare, inherited skin scaling disorder (NIPAL4 ichthyosis) also develop a serious type of blood cancer called Sézary syndrome. Researchers will analyze the immune cells in the blood of 10 adult patients who have the skin conditi…

This study aims to understand what happens to couples after they go through IVF with genetic testing (PGT) to prevent passing on a severe inherited disease, but do not have a baby from the process. Researchers will follow 900 couples from a Paris clinic to learn about their emoti…

This study aims to create a detailed map of the different types of hepatitis C virus circulating in France. Researchers will analyze existing blood samples and medical records from 2,500 newly diagnosed patients to identify which virus types are most common. The goal is to unders…

This study aims to create the first national database of patients with SITRAME syndrome, a rare autoimmune disease. Researchers will collect information from 100 French patients to understand who gets the disease, how it progresses, and what treatments are used. The goal is to ga…

This study aims to better understand how a rare genetic disorder, enamel renal syndrome, affects kidney function and causes harmful calcium deposits in blood vessels. Researchers will compare detailed test results from 30 adults with the condition to results from healthy voluntee…

This study aims to better understand how the lungs work in brain-injured patients who are trying to stop using a ventilator. Researchers will use a special belt with sensors to take pictures of how air moves in different parts of the lungs. They hope to find patterns that can pre…

This study aims to understand how sepsis (a severe infection) changes the immune system's activity over time. Researchers will follow 290 people—including sepsis patients, other critically ill patients, and healthy volunteers—for up to 12 months after their ICU stay. By analyzing…

This study aims to understand why some cancer patients develop neurological problems after receiving immunotherapy drugs. Researchers will analyze spinal fluid and blood from 160 participants, including cancer patients with these side effects and people with other neurological co…

This study aims to understand the biological causes of autism spectrum disorder (ASD) by creating brain-like models called organoids from blood cells. Researchers will compare organoids from children with ASD to those from their unaffected siblings. The goal is to identify cellul…

This study aims to understand why some women experience repeated IVF failures or miscarriages. Researchers will compare uterine tissue and blood samples from women with these histories to women without them, looking for differences in immune cells and bacteria. The goal is to ide…

This study aims to understand and track memory and thinking problems (often called 'chemo fog') in people with early-stage, operable lung cancer. Researchers will observe 90 patients to see when these issues start, how long they last, and what makes them worse or better. The goal…

This study aims to see if a computer can predict what word a patient says by reading their brain activity during awake brain tumor surgery. Researchers will record brain signals from 20 adult patients while they name pictures, as part of their standard surgical mapping. The goal …

This study aims to understand the real-life experiences of patients with prosthetic joint infections, their families, and their healthcare teams. Researchers will conduct interviews and group discussions to learn about the challenges of this serious condition. The goal is to use …

This study aims to find better, more objective ways to program cochlear implants for adults with severe hearing loss. Currently, programming relies heavily on a patient's subjective feedback about what sounds comfortable. Researchers will follow 60 adults, some getting a new impl…

This study aims to gather information on the safety of intrauterine devices (IUDs) and menstrual products like tampons and cups for women with primary immune deficiency diseases. Researchers will survey 200 adult women with these rare genetic conditions to see which products they…

This study aims to understand why and how heart problems develop in patients receiving stem cell transplants for blood cancers. Researchers will follow 400 transplant patients for one year, using heart scans, blood tests, and health tracking to identify early warning signs of hea…

This study aims to understand how disorders in blood cell production are connected to various inflammatory and autoimmune diseases. Researchers will observe 5,000 adult patients who have these conditions, collecting their health information over time. The goal is to create a deta…

This study aims to better understand severe, life-threatening skin and soft tissue infections (often called flesh-eating infections) by tracking 1000 patients in the Paris area. Researchers will follow patients' recovery, quality of life, and treatment outcomes to identify what f…

This study aims to understand the overall health of doctors-in-training (residents) at a Paris hospital. It will check their physical, mental, and sexual health, as well as their access to care. The goal is to get a complete picture of their wellbeing to find ways to better suppo…

This study aims to discover biological markers that can predict how inflammatory bowel diseases (IBD) like Crohn's and ulcerative colitis will progress and how patients will respond to treatments. It will follow 4,500 participants, including people with IBD and healthy controls, …

This study aims to understand the healthcare journey of young people (ages 12-25) with somatic symptom disorder—a condition where they experience distressing physical symptoms that doctors can't fully explain by another medical condition. Researchers will interview 36 patients an…

This study will create a registry of 5000 French patients with hypertrophic cardiomyopathy, a condition where the heart muscle becomes abnormally thick. Researchers will analyze existing heart MRI scans to develop a better scoring system for predicting which patients are at highe…

This study aims to better understand social thinking skills in children with neurodevelopmental conditions like autism and ADHD. Researchers will test a new set of assessment tasks with 100 children and teens aged 8-16 to measure how they process emotions, understand others' pers…

This study aims to understand Congenital Central Hypoventilation Syndrome (CCHS), a rare disorder where people don't breathe automatically, especially during sleep. Researchers will collect and analyze blood and urine samples from 40 adults with CCHS and healthy volunteers to loo…

This study aims to understand how specialized Multiple Sclerosis Care Units (MSCUs) help coordinate care between different doctors and services. Researchers will interview patients, caregivers, and healthcare professionals in France and Italy to learn what makes care pathways wor…

This study aims to better understand why people with autoimmune diseases like lupus have a higher risk of heart problems. Researchers will collect heart scan results and health information from 1,500 patients over time to identify early warning signs. The goal is to learn which p…

This study aims to understand how well a common antibiotic (cefazolin) reaches the chest area in young children after heart surgery. Researchers will place a tiny probe during surgery to measure antibiotic levels directly in the tissue over 28 hours. The goal is to gather informa…

This study aims to validate a French version of a questionnaire that measures how people's smile appearance affects their quality of life. Researchers will recruit 120 adult patients visiting dental departments at two Paris hospitals. Participants will complete the questionnaire …

This study aims to gather information to improve how doctors protect patients' lungs during surgery. It will observe 34 adults having long surgeries while using special monitors to see if they can better guide ventilator settings. The goal is to learn if this monitoring can help …

This study aims to understand how a newer heart procedure called pulse-field ablation changes the structure of the heart's upper chambers (atria) in people with atrial fibrillation. Researchers will compare detailed CT scans taken before and after the procedure in 200 patients to…

This study aims to understand what happens to patients who experience a sudden, severe worsening of their pulmonary hypertension, a condition where high blood pressure in the lungs strains the heart. Researchers will track 200 patients across Europe who are hospitalized for this …

This study aims to understand why patients with severe lung failure (ARDS) respond differently to treatment. Researchers will analyze blood and lung fluid from 50 ICU patients on breathing machines to map their immune system activity. The goal is to identify different biological …

This study aims to understand how heart artery disease progresses over time in people with a genetic condition causing very high cholesterol. Researchers will use detailed heart scans to track changes in artery plaque in 300 participants over 5 years, with health record follow-up…

This study aims to create the first-ever lab-grown cells from the human diaphragm, the main breathing muscle. Researchers will collect small tissue samples from 10 people undergoing surgery for a separate condition. By comparing these new diaphragm cells to existing arm muscle ce…

This study aims to create a French version of a tool used to assess pain in newborn babies. Researchers will work with healthcare professionals to translate and adapt the COMFORTneo scale, which is already used in other countries. The goal is to provide French neonatal units with…

This study aims to create a large, unified database by combining existing medical and research data from children and young adults with acute myeloid leukemia (AML) in France. The goal is to find hidden patterns by studying many patients together, which is hard to do for rare dis…

This study aims to understand if a special pre-surgery scan helps prevent spinal cord damage during operations to remove certain childhood chest tumors. Researchers will look back at the medical records of 150 children in France who had this surgery between 2005 and 2024. They wi…

This research study aims to understand how bacteria, fungi, and viruses living on the skin and in the gut might relate to Netherton syndrome, a rare genetic skin condition. Researchers will compare samples from about 30 patients (ages 10+) with samples from healthy volunteers. Th…

This study aims to create a detailed map of how genes work in the human placenta from early pregnancy to birth. Researchers will collect and analyze small placenta samples from 100 pregnant volunteers at two time points. The goal is to understand normal development and identify e…

This study aims to understand why some people with severe nearsightedness develop an abnormal bulging at the back of the eye, called a posterior staphyloma. Researchers will compare 600 European adults with severe nearsightedness—half with this condition and half without—by colle…

This study follows 450 people with diabetes over time to understand if low levels of a nutrient called glutamine in their blood are linked to a higher risk of future heart problems like heart attacks or strokes. It is an observational study, meaning researchers will collect blood…

This study is testing a mobile app called Resilience PRO to see if it can help patients with a specific type of brain tumor (IDH-mutant glioma) better manage their symptoms and quality of life. The app will send weekly surveys to 80 patients to track their symptoms, fatigue, and …

This study aims to see if a blood test can track childhood leukemia as effectively as current painful bone marrow tests. Researchers will compare cancer DNA found in blood samples with DNA from bone marrow samples taken at key treatment points. The goal is to find a less invasive…

This study aims to understand why children with ulcerative colitis are more likely to get serious C. difficile infections. Researchers will compare stool samples from 80 children across four groups: those with active colitis with and without the infection, those whose colitis is …

This study aims to understand why patients respond differently to the heart medication mavacamten, which treats a condition called obstructive hypertrophic cardiomyopathy. Researchers will collect genetic and health data from 300 patients already taking the drug to see if a perso…

This study aims to develop better brain scans for very premature babies. Researchers will use a new 3D ultrasound technique to look for tiny brain injuries in 360 infants born before 30 weeks. The goal is to see if these early scans can predict which children might have thinking …

This study aims to understand which type of speech therapy works best for young children with severe hearing loss who use cochlear implants. Researchers will observe 60 children to see how two different therapy approaches affect their ability to understand and use language. The g…

This study aims to understand how living kidney donors feel about receiving a symbolic form of recognition, like a commemorative medal, after their donation. Researchers will interview 15 people who have donated a kidney to learn if such recognition could improve their experience…

This study aims to create a reference standard for a new, simpler way to analyze how children walk. Researchers will use a system with just four cameras to record the walking patterns of 125 healthy children. The goal is to later use this reference to better understand and treat …

This study aims to better understand how the brain responds to anesthesia and sedation by observing brain wave patterns. It will enroll 330 participants, including children, elderly adults, and people undergoing sedation for procedures. Researchers will use standard brain monitor…

This study aims to understand how a common virus called CMV might weaken the immune system of kidney transplant patients, making them more susceptible to other serious infections. Researchers will compare the immune responses of 60 transplant patients with and without active CMV …

This study is looking back at the medical records and heart MRI scans of 5,000 people in France who had myocarditis (heart inflammation). The goal is to understand how the patterns seen on these scans relate to long-term health outcomes like survival and heart problems. This know…

This study aims to understand if surgery for a specific brain tumor (craniopharyngioma) changes what foods people like, particularly high-fat and high-sugar items. Researchers will compare food preferences in adults who had this surgery to other patient groups and healthy people.…

This study aims to understand the connection between the brain and lungs in adults admitted to intensive care with sudden, severe breathing failure. Researchers will use non-invasive sensors to measure brain and muscle activity before and after patients start a high-flow oxygen t…

This study aims to find biological markers (biomarkers) in the blood and tissues of adults with rare inflammatory diseases called systemic histiocytoses. By studying 500 patients, researchers hope to better understand what causes these diseases, predict how they will progress, an…

This study aims to understand how brain lesions change on MRI or CT scans in people being treated for a rare brain infection called nocardiosis. Researchers will look back at the medical records and brain scans of 60 patients who have already been treated. The goal is to see if c…