Ain Shams University

This study tests two surgical methods to correct large-angle exotropia (a type of crossed eyes) using only one eye. One method moves a piece of muscle to the side, the other splits the muscle in a Y-shape. Researchers will measure how straight the eyes become and check for any si…

This pilot study compares two surgical techniques for closing idiopathic macular holes: using a Tenon capsule graft versus the standard internal limiting membrane (ILM) flap. Twenty participants will undergo vitrectomy and be assigned to one of the two groups. The study will meas…

This study tests a systematic approach for treating orbital lymphatic malformation in children aged 1-18. Participants are split into three groups: one gets sclerotherapy (injections to shrink the lesion), one gets the drug sirolimus, and one gets both. The goal is to see if siro…

This study compares two laparoscopic surgeries for apical prolapse, a common condition in aging women. The standard surgery, sacrocolpopexy, is effective but technically challenging. The newer pectopexy may be safer and faster to learn. Thirty women with advanced prolapse will be…

This study tests whether a manuka honey mouthwash can improve gum health in people with kidney failure who are on dialysis and also have gum disease. About 150 adults will rinse with a diluted manuka honey solution three times a day. Researchers will measure changes in gum attach…

This study tests whether a 3D-printed dental expander works better than a traditional one for widening the upper jaw in teenagers aged 12 to 17. Twenty-two teens with a narrow upper jaw will receive either a custom 3D-printed or a conventionally made expander. The goal is to see …

This trial compares two ways to lift the sinus floor before placing dental implants in the upper jaw. One method uses special drills, the other uses a tool called an osteotome. The goal is to see which gives more bone gain and better implant stability. Twenty adults with missing …

This study compares three different root canal dressings used between visits in retreatment cases. The goal is to see which one best reduces inflammation, shrinks infection-related lesions, and lowers pain. Sixty adults with previously treated but still infected lower first molar…

This study tests a new 3D printed aligner for infants born with a complete cleft lip and palate. The device aims to make nasoalveolar molding (a treatment that reshapes the gums and nose before surgery) more accurate and easier to use. Twenty infants under 45 days old will receiv…

This study compares two modern, minimally invasive surgeries for removing kidney stones that are 2-3 cm in size. About 120 adults will be randomly assigned to either mini-percutaneous nephrolithotomy (Mini-PCNL) or flexible ureteroscopy with a suction sheath. The goal is to see w…

This study tests a stepwise feeding plan for children in the pediatric intensive care unit (PICU). The goal is to see if following a clear, step-by-step protocol helps kids reach their full nutrition needs sooner and reduces feeding interruptions. Researchers will compare how lon…

This study compares three different single-use flexible ureteroscopes used to remove kidney stones. Researchers will look at cost, how long the surgery takes, complications, and how well the stones are cleared. About 180 adults with small-to-medium kidney stones will take part.

This study tests a shorter, more intense radiation schedule combined with chemotherapy for cervical cancer. The goal is to see if this approach works as well or better than standard treatment, while reducing overall treatment time. About 30 adults with stage II or III cervical ca…

This study tests whether N-acetyl cysteine (NAC), a safe supplement, can reduce oxidative stress and improve eye health in people with type 2 diabetes who have mild to moderate diabetic retinopathy. About 76 adults aged 18-70 will take NAC to see if it lowers damage to blood vess…

This study tests if the heart drug nebivolol can protect the hearts of women with HER2-positive breast cancer who are receiving trastuzumab, a treatment that can weaken the heart. Researchers will measure heart function and quality of life in 56 participants over several months. …

This study looks at whether two simple blood test results—the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio—can help predict which children with severe burns will develop acute respiratory distress syndrome (ARDS), a serious lung condition. Researchers will foll…

This study tests whether vitamin K2 supplements can prevent bone loss in children with nephrotic syndrome who are on long-term steroid therapy. Steroids are effective but can weaken bones, increasing fracture risk. The trial will enroll 60 children under 16 and measure changes in…

This study tests two drugs—hydrocortisone and dexmedetomidine—to see which better prevents shivering after abdominal surgery under general anesthesia. 70 adults will be randomly assigned to receive one drug before the end of surgery. The goal is to find a safe, effective way to k…

This study tests whether taking alpha lipoic acid, a common antioxidant supplement, can prevent or reduce skin irritation caused by radiation therapy in breast cancer patients. Researchers will enroll 40 women with early-stage breast cancer who are scheduled for radiation. The go…

This study tests whether giving women a carbohydrate drink with added nitrates (from beet root extract) before open gynecological surgery can shorten their hospital stay. The idea is that the combination may reduce stress from surgery and improve recovery. About 90 women aged 18-…

This study compares two sedation approaches—dormicum-ketamine versus dexmedetomidine—to see which better prevents emergence delirium (confusion and agitation) in children aged 3 to 16 with burns. Sixty kids undergoing burn dressing changes or minor procedures will be randomly ass…

This study looks at whether adding dexmedetomidine to the standard numbing drug bupivacaine in a caudal block (a type of pain shot near the tailbone) can give children longer pain relief after open appendix surgery. Sixty children will be randomly assigned to get either the combo…

This study tests a 10-week behavioral training program designed to boost resilience and reduce stress in nursing students. 90 students will either take the program during the semester or wait until after. Researchers will measure changes in stress and resilience using questionnai…

This study compares two methods for controlling pain after hip surgery: a nerve block (fascia iliaca compartment block) and a spinal injection of nalbuphine. 120 adults having hip surgery under spinal anesthesia will be randomly assigned to one of the two methods. The main goal i…

This study tests a newer way to give epidural steroid injections for people with long-term leg pain caused by nerve issues. It compares the new 'transgrade' method to the standard 'interlaminar' method. The goal is to see which approach provides better pain relief three months af…

This study compares two ultrasound-guided nerve blocks—M-TAPA and quadratus lumborum block—for pain after laparoscopic gallbladder removal. Fifty-two adults undergoing surgery will receive one of the two blocks, and researchers will measure how long it takes before they need addi…

This study tests whether high-level laser therapy can help manage oral mucositis—painful mouth sores—in children under 18 who are having a bone marrow transplant. Fourteen participants will receive either laser treatment or standard mouth care (chlorhexidine and sodium bicarbonat…

This study tests if giving ketamine before laparoscopic sleeve gastrectomy (a type of weight-loss surgery) can reduce pain after the operation. Researchers will compare how long it takes for patients to need extra pain medicine. The study includes 90 adults with a BMI between 35 …

This study tests three ways to fix black triangles—the small, dark gaps between teeth caused by missing gum tissue. Thirty adults will receive either a surgical gum graft, a gel injection, or a tooth-colored filling. Researchers will measure how well each method closes the gap an…

This study compares two minimally invasive procedures—water vapor therapy (Rezum) and prostatic artery embolization—for men with moderate-to-severe enlarged prostate symptoms. About 30 men aged 50 and older who haven't responded to medication will be followed for 6 months to see …

This study compares two ultrasound-guided nerve block techniques for distal upper limb surgery to see which one numbs the arm faster. Fifty adults having arm or hand surgery will be randomly assigned to receive one of the two blocks. The goal is to improve patient comfort and spe…

This study tests two treatments for white spots on front teeth that often appear after braces. It involves 18 people aged 15 to 25. Each person gets both treatments—one on each side of the mouth—to see which works better at improving tooth color and reducing spot size. Results wi…

This study tests whether a lidocaine nasal spray can reduce pain and the need for strong opioid drugs during partial turbinectomy (nose) surgery. About 50 adults having this surgery will receive either the spray or a placebo. The goal is to see if the spray helps patients recover…

This study tests whether itopride, a drug that helps the stomach empty faster, can reduce the risk of food or liquid staying in the stomach after 8 hours of fasting in people taking semaglutide. About 60 diabetic patients scheduled for hysterectomy will be randomly assigned to re…

This study tests two different methods to re-inflate the lungs after weight-loss surgery. About 100 adults having laparoscopic bariatric surgery will receive one of two breathing techniques right before waking up from anesthesia. The goal is to see which method improves oxygen le…

This study tests whether a combination of two drugs—tamsulosin and a lower dose of tadalafil—can reduce uncomfortable symptoms caused by a ureteric stent placed after kidney stone removal. About 140 adults who have a stent after stone surgery will receive either the standard or h…

This study compares two ways of giving fentanyl (a painkiller) to preterm babies undergoing painful procedures like inserting a breathing tube or a central line. One method uses a tiny spray into the nose, the other uses an IV needle. The goal is to see if the nose spray works ju…

This study tests whether two natural supplements—silymarin (from milk thistle) and a hesperidin/diosmin combination (from citrus)—can reduce pain and improve quality of life in people with fibromyalgia. About 90 adults with fibromyalgia will take one of the supplements or a place…

This study compares two types of nerve blocks—erector spinae plane block and serratus anterior plane block—to see which one controls pain better after video-assisted lung surgery. About 50 adults aged 25 to 70 having lung procedures like lobectomy or pleurectomy will take part. T…

This study compares two pain-relief cocktails given during back surgery to see which works better. 72 adults having lumbosacral surgery will receive either dexmedetomidine or ketamine added to the standard numbing drug bupivacaine. The goal is to extend pain relief after surgery …

This study tests if a newer ultrasound-guided nerve block can control pain after hemorrhoid surgery as well as the standard saddle block. Fifty adults aged 18 to 65 having hemorrhoid removal will be randomly assigned to one of the two methods. Researchers will track pain scores a…

This study looks at two different ultrasound techniques to help doctors decide how much fluid to give patients with septic shock. One method measures the heart's left ventricle, while the other checks blood flow in the carotid artery. The goal is to see which is more accurate at …

This study is testing whether a simple neck ultrasound can predict dangerous drops in blood pressure after anesthesia in adults with chronic liver disease. Researchers will measure blood flow in the carotid artery before and after anesthesia in 35 patients. If the method works, i…

This study looks at whether levels of a substance called PGE2 in the blood can predict which premature babies (born at 32 weeks or earlier) will develop a serious heart condition called patent ductus arteriosus (PDA). Researchers will measure PGE2 levels and use heart ultrasounds…

This study is looking at whether a blood test called D-dimer can help doctors understand how serious pneumonia is and how well patients might recover. Researchers will measure D-dimer levels in 50 adults admitted to the hospital with community-acquired pneumonia and compare them …

This study is testing whether ultrasound can measure breathing muscle strength in ICU patients on ventilators. The goal is to see if these measurements can predict who will successfully wean off the machine. Researchers will enroll 77 adults who have been on a ventilator for more…

This study compares using ultrasound versus an age-based formula to choose the correct breathing tube size for children aged 3 months to 8 years with single ventricle heart conditions. The goal is to see which method leads to fewer breathing tube placement attempts and less post-…

This study looks at 290 intensive care patients with sepsis to see which blood test best predicts their chance of recovery. Researchers will compare three different markers in the blood to see which one most accurately forecasts survival at 28 days. The goal is to help doctors id…

This study is looking at whether taking psychotropic medications (drugs that affect mood or thinking) raises the risk of falls in older adults. Researchers will follow 398 people aged 60 and older after they leave the hospital, tracking falls and fractures over one year. The goal…

This study looks at how quickly people can bite and slide their teeth when wearing a lower denture held in by either two regular-sized implants or four smaller mini-implants. Researchers will measure the time it takes to close the bite and to slide the teeth apart. The goal is to…

This study compares two widely used inhaled anesthetics, isoflurane and sevoflurane, to see which one causes less oxidative stress (a type of cell damage) in patients having gallbladder removal surgery. Researchers will measure stress markers in the blood of 80 adults before and …

This study looks at three different scoring systems to see which one best predicts the risk of death in patients with severe tetanus in the intensive care unit. Researchers will follow 115 adults with tetanus for up to 90 days. The goal is to find the most accurate tool to help d…

This study tests which method is more accurate for placing dental implants: a custom-made guide or a dynamic navigation system that shows the dentist where to drill on a screen. Twenty healthy adults with at least one missing upper tooth will take part. The goal is to see which a…

This study uses bedside ultrasound to measure muscle loss, fat changes, and fluid buildup in critically ill pregnant and gynecological patients. Researchers will track 121 women in the ICU to see if these body changes relate to serious outcomes like death, need for a breathing ma…

This study looks at whether a simple ultrasound test before surgery can predict if a patient will have dangerously low blood pressure after receiving anesthesia for brain surgery. Researchers will measure the size and flexibility of a major vein and artery using ultrasound in 36 …

This study looks at how lung ultrasound can help find lung issues early in women who are critically ill due to pregnancy complications or gynecologic cancer. Researchers will check for different lung ultrasound patterns and see if they relate to patient outcomes like death or nee…

This study looks at whether a quick breathing measurement, called the Rapid Shallow Breathing Index, can help doctors decide when it's safe to remove a breathing tube from patients in the intensive care unit. About 70 adults on ventilators will be monitored after tube removal to …

This study looks at whether measuring how much a vein near the armpit collapses with breathing can predict if a sepsis patient needs more fluids. It involves 40 spontaneously breathing adults with sepsis and signs of poor circulation. The goal is to find a simple, non-invasive wa…

This study looks at whether using a blood test (anti-Xa) to adjust the dose of a blood thinner (enoxaparin) works better than dosing based on weight alone for preventing dangerous blood clots in burn patients. About 25 adults with serious burns will be enrolled. The goal is to se…