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Can a common supplement heal diabetic foot ulcers faster?

NCT ID NCT07768228

Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time

Summary

This phase 2 trial investigates whether oral L-carnitine, a natural compound, can improve wound healing in people with diabetic foot ulcers. Researchers will measure changes in ulcer size and depth over 12 weeks, along with markers like VEGF, inflammation, and blood sugar control. The study includes 50 adults with mild-to-moderate diabetic foot ulcers and aims to see if this supplement offers a safe, effective way to support healing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
oral L-carnitine
What this could lead to
If effective, L-carnitine could become a simple, low-cost addition to standard care for diabetic foot ulcers, potentially speeding healing and reducing complications.
What could go wrong
This is a small, early-stage trial. The supplement may not significantly improve healing, and results may not apply to all patients with diabetic foot ulcers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult Male or Female patients with diabetic neuropathy mean age (30-75) years old. * Having Diabetic neuropathy and Diabetic foot ulcer grade 1-2 (mild- moderate) according to Wagner classification. * Uncontrolled diabetic patients (HbA1c). \< 9 duration of diabetic (5 - 10) years. * All patient treated with stable dose of anti-diabetic medication priors and during the period of the study. Exclusion Criteria: * Patients with other causes of ulcers. * Patient taking any antioxidant supplements including vitamin E, ascorbic acid, omega 3 fatty acid, Coenzyme Q10 within three months prior to enrollment in the study. * Patient with autoimmune disease. * Patient with liver disease or kidney disease. * Patient taking medications for cancer. * Patient with thyroid disease.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetic foot ulcer Diabetic foot ulcer (DFU)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Pharmacy, Ain Shams University

    RECRUITING

    Cairo, Cairo Governorate, 11566, Egypt

  • Faculty of Pharmacy, Ain Shams University

    ACTIVE_NOT_RECRUITING

    Cairo, Cairo Governorate, 11566, Egypt

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