DIABETIC FOOT ULCER

This study tests whether negative pressure wound therapy (a special vacuum dressing) works better than standard wound care for diabetic foot ulcers after surgery. Researchers will track 50 adults over one year to see if this treatment reduces the need for leg amputations, extra s…

This study tests a gel called ENERGI-F703 on diabetic foot ulcers that haven't healed for at least 4 weeks. About 230 adults with diabetes will use either the gel or a placebo for 16 weeks. The main goal is to see if the gel helps the wound close completely and stay closed for 2 …

This study tests whether adding a special dressing called EDX110 to usual care helps diabetic foot ulcers heal better than usual care alone. About 298 adults with a non-healing foot ulcer will be randomly assigned to receive either the EDX110 dressing plus standard care, or stand…

This early-stage study tests a topical spray called ELU42 for diabetic foot ulcers that have not healed for at least 4 weeks. The goal is to see if the spray is safe and can shrink or close these wounds. Fifteen adults with mild-to-moderate ulcers will receive the spray three tim…

This study tests whether a product called NeoThelium FT, used with standard wound care, helps diabetic foot ulcers close faster than standard care alone. About 132 adults with diabetes and a foot ulcer that has lasted at least 4 weeks will take part. The main goal is to see if th…

This study tests whether adding a special gel called Omeza Complete Matrix to standard wound care helps diabetic foot ulcers heal completely within 12 weeks. About 130 adults with diabetes and a foot ulcer that has lasted at least 4 weeks will take part. Researchers will compare …

This study tests whether a special graft made from donated placental tissue can help heal diabetic foot ulcers that won't close with standard care. About 60 adults with type 1 or 2 diabetes will receive either the graft plus usual wound care or usual care alone. The main goal is …

This study tests a new wound dressing for diabetic foot ulcers in 100 adults with diabetes. Participants will receive either the new dressing or standard NHS care during their regular podiatry visits. The main goal is to see if the new dressing leads to complete wound healing wit…

This study tests whether adding a special amniotic membrane graft (Orion™) to standard wound care helps heal diabetic foot ulcers faster in people over 50. About 240 participants will be split into two groups: one gets standard care alone, the other gets standard care plus the gr…

This study tests a gel called BB-101 on diabetic foot and leg ulcers. About 96 adults with diabetes will receive either the gel or a placebo to see if it helps wounds close faster. The goal is to find a safe, effective way to treat these stubborn sores.

This study tests a skin graft called NeoThelium FT to see if it helps heal diabetic foot ulcers in people with diabetes. Ten adults with mild to moderate foot ulcers will receive the graft. The main goal is to see if the wound closes completely and stays closed for two weeks.

This study tests whether using a special walking analysis and custom shoe inserts can reduce the chance of new foot ulcers or amputations in people who have had a diabetic foot ulcer before. About 69 adults with healed foot ulcers will be followed to see if this approach lowers t…

This study tests whether a special wound dressing made from dehydrated human placenta tissue, used along with standard wound care, can help close diabetic foot ulcers faster than standard care alone. About 120 adults with diabetes and a foot ulcer that hasn't healed for at least …

This study follows 50 people whose diabetic foot ulcers healed completely in an earlier trial. Researchers want to see how often the ulcers come back after treatment with a special amniotic membrane plus standard care versus standard care alone. Participants will be monitored usi…

This study tests whether a special placental graft, used alongside standard wound care, can help close diabetic foot ulcers that won't heal on their own. About 350 adults with type 1 or 2 diabetes and a foot ulcer between 1 and 15 cm² will be randomly assigned to receive the graf…

This study compares two new skin grafts (PelloGraft and SanoGraft) to standard care for treating diabetic foot ulcers and venous leg ulcers. About 180 adults with these hard-to-heal wounds will be enrolled. The goal is to see if the grafts help wounds close completely within 12 t…

This study tests whether a special wound covering made from donated placental membrane can help heal diabetic foot ulcers and venous leg ulcers that won't close with standard care alone. About 50 adults with diabetes or vein problems will receive either standard wound care plus t…

This study tests a device that combines light and magnetic pulses to help heal diabetic foot ulcers that have not closed with standard care. About 450 adults with these stubborn wounds will either get the real device or a fake (sham) device, plus usual wound care. The main goal i…

This study tests whether special smart insoles can help prevent foot ulcers from coming back in people with diabetes and nerve damage. The insoles measure pressure and temperature on the feet and alert the user to problem areas. 400 high-risk participants will be followed to see …

This study is testing a device called FlowOx that uses gentle suction on the foot for one hour, twice a day, for 12 weeks. The goal is to see if it improves blood flow and helps heal foot ulcers in people with diabetes. About 30 adults with diabetes and foot ulcers will use the d…

This study tests a program called CARE-D-Foot-Nav, which assigns a patient navigator to help adults with diabetes and foot ulcers manage their care. The goal is to see if this extra support leads to more ulcers healing completely within 20 weeks compared to usual care. The study …

This study tests three types of diabetic boots to see which helps people wear them more consistently. Diabetic foot ulcers can lead to amputation if not treated properly, and wearing a special boot is key to healing. One boot uses a smartwatch and phone to remind and track wear t…

This study is testing a special soft cast for diabetic foot ulcers. Researchers want to see if it helps ulcers heal completely, is comfortable, and safe to use. The study will include 100 adults with diabetic foot ulcers. Participants will use the cast until their ulcer heals or …

This study follows 1000 adults with diabetic foot ulcers for up to 5 years. Researchers want to learn why these patients have a higher risk of death and what factors contribute. The goal is to create a risk score to identify those most in need of extra care.

This study reviews medical records of 200 patients with diabetic foot ulcers admitted to a hospital in Iran in 2024. Researchers will look at lab results like blood sugar and inflammation levels to see how they relate to ulcer severity. The goal is to find patterns that could hel…

This study aims to find biological markers (biomarkers) that can predict whether a diabetic foot ulcer will heal or not. Researchers will collect samples like blood and wound fluid from 5,000 adults with diabetes and an open foot ulcer. The goal is to develop tools that help doct…