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Could placental wraps heal stubborn ulcers? new trial begins

NCT ID NCT07364630

First seen Feb 01, 2026 · Last updated Jun 22, 2026 · Updated 23 times

Summary

This study tests whether special wraps made from human placental membrane can help heal diabetic foot ulcers and venous leg ulcers that won't close on their own. About 50 adults with diabetes or venous disease will receive weekly applications of one of four placental membrane products plus standard care for up to 12 weeks. The main goal is to see how many ulcers fully close during that time.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Foot and Ankle Disorders

    RECRUITING

    Philidelphia, Pennsylvania, 19146, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

human placental membrane wraps (Tri-Membrane Wrap, Membrane Wrap, Membrane Wrap-Lite, Membrane Wrap-Hydro)

What this could lead to

If successful, these placental membrane wraps could offer a new, effective option to help heal stubborn diabetic foot and venous leg ulcers faster.

What could go wrong

This is a small, early-phase trial with only 50 participants, so results may not apply to everyone. The treatment is applied weekly for up to 12 weeks, and there is a risk of infection or other side effects.

Conditions

The condition(s) this trial relates to.

chronic venous insufficiency Diabetic Foot Foot Ulcer Leg Ulcer ulcer disease ulcer of lower limbs Varicose Ulcer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.