TYPE 2 DIABETES MELLITUS

This early study is testing a new procedure that uses radiofrequency (RF) energy to treat a small part of the upper intestine in people with type 2 diabetes. The goal is to see if it is safe and can help lower blood sugar levels. About 20 adults with type 2 diabetes who are not o…

This study watches 300 adults with type 2 diabetes who are already taking the drug luseogliflozin (Lusefi®) as part of their normal care. Researchers will track changes in blood sugar, weight, and blood pressure over time to see how effective and tolerable the drug is in real-wor…

This study tests a new combination medicine called Madalena association for people with type 2 diabetes whose blood sugar is not well controlled with two other diabetes drugs. About 270 adults will receive either the new drug or a placebo to see if it safely lowers HbA1c levels. …

This study tests a new weekly injection called enicepatide in 1600 adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if it helps with weight loss compared to a placebo over 72 weeks. Participants must be on stable diabetes treatment and h…

This study checks if a new insulin pump (NMX8) is safe when used with a continuous glucose monitor in people with type 1 or type 2 diabetes. About 400 participants aged 7 to 85 will use their usual therapy with the sensor for up to 40 days, then use the new pump for 90 days. The …

This study tests whether a continuous glucose monitor (CGM) called Accu-Chek SmartGuide helps adults with type 1 or type 2 diabetes spend more time with blood sugar in the target range (70-180 mg/dL) compared to standard fingerstick testing. About 270 adults who use daily insulin…

This early-stage study tests whether a new drug, maridebart cafraglutide, can help the body use insulin better in people with type 2 diabetes. About 57 adults aged 18 to 70 who are already taking metformin will receive either the drug or a placebo. The main goal is to measure cha…

This study looks at whether a structured clinical and medication management plan can improve heart health in adults with risk factors like high blood pressure, diabetes, and high cholesterol. Researchers will track 220 patients in a regular cardiology clinic to see if this approa…

This study tests an experimental cell therapy called REACT (rilparencel) in 685 adults with type 2 diabetes and chronic kidney disease. The goal is to see if up to two injections can slow the loss of kidney function compared to a sham procedure. Participants will be followed for …

This study tests whether personalized marketing and discounts in an online grocery store can encourage people with prediabetes or type 2 diabetes to buy more whole grains instead of refined grains. About 216 adults aged 45-70 from Pennsylvania who already shop online for grocerie…

This study checks how accurate a new glucose sensor called LabPatch is at measuring blood sugar in people with diabetes who use insulin. About 60 adults with type 1 or type 2 diabetes will wear the sensor during a 6-hour visit. Their readings will be compared to standard lab test…

This study aims to find out how common chronic kidney disease (CKD) is in semi-rural Sub-Saharan Africa and what factors increase the risk. Researchers will follow 1,200 adults for one year, measuring kidney function and checking for conditions like diabetes, high blood pressure,…

This study is observing 500 adults in South Korea with chronic kidney disease and type 2 diabetes who are taking the medication finerenone as part of their regular care. Researchers want to learn why doctors prescribe it, how long patients stay on it, and what side effects occur.…

This study is looking at whether the texture of the carotid artery wall, seen on an ultrasound, can help predict the risk of heart problems in people with type 2 diabetes. Researchers will compare ultrasound images from 80 adults with and without diabetes. The goal is to find a b…

This study looks at how certain genes influence the effectiveness of common diabetes drugs like exenatide and liraglutide in people with type 2 diabetes. Researchers will analyze blood samples and health data from 300 participants to find genetic markers that predict better blood…

This study looks at real-world data from 50,000 people in Asia and the US who have both chronic kidney disease and type 2 diabetes and are taking the drug finerenone as part of their regular care. Researchers will collect information on patients' age, other health conditions, and…

This study looks at whether the standard A1C blood sugar test is accurate for people with type 2 diabetes who have a Left Ventricular Assist Device (LVAD). Researchers will compare A1C results with data from a continuous glucose monitor (CGM) worn for 3 months. The goal is to see…