Type 2 diabetes mellitus
Clinical trials for Type 2 diabetes mellitus explained in plain language.
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New pill takes aim at stubborn blood sugar
Disease control Stopped earlyResearchers are testing an experimental oral drug called MBX-102 in adults with type 2 diabetes whose blood sugar remains too high on metformin alone. The trial compares two doses of MBX-102 with a placebo and with Actos, an approved diabetes drug. About 242 participants take the…
Matched conditions: TYPE 2 DIABETES MELLITUS
Phase 2 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Can cutting carbs and a diabetes drug help kidneys?
Disease control Stopped earlyThis small pilot study tested whether a low-carb diet (50-100 grams of carbs per day) combined with the diabetes drug dapagliflozin could improve blood sugar control in people with chronic kidney disease and prediabetes or type 2 diabetes. Four participants were split into two gr…
Matched conditions: TYPE 2 DIABETES MELLITUS
Sponsor: Department of Nephrology Clinic Ottakring Vienna • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Insulin showdown: toujeo vs tresiba for diabetics with kidney disease
Disease control Stopped earlyThis study compared two long-acting insulins, Toujeo and Tresiba, in people with type 2 diabetes who also have kidney problems and had never used insulin before. The goal was to see which one controls blood sugar better and causes fewer low blood sugar events. The trial was stopp…
Matched conditions: TYPE 2 DIABETES MELLITUS
Phase 4 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 26, 2026 14:43 UTC