MIGRAINE

This study looked at whether taking rimegepant every day or every other day can help prevent migraines in people who have 4 to 14 migraine days per month. Over 1400 adults participated, and researchers compared both dosing schedules to a placebo. The goal was to see which schedul…

This study tested whether a monthly injection of fremanezumab can prevent chronic migraines in children aged 6 to 17. About 292 participants received either the drug or a placebo, and researchers tracked how many headache days they had over 12 weeks. The goal was to see if the dr…

This study tested whether adding eptinezumab (a migraine prevention drug) to a brief educational program helps adults who have both migraines and medication overuse headache. Over 600 participants were followed to see if the drug reduced the number of migraine days and headache d…

This study tested a drug called eptinezumab to see if it could prevent migraines in people with chronic migraine (15 or more headache days per month, at least 8 being migraine). About 981 adults took part. The main goal was to see if the drug reduced the number of migraine days e…

This study looked at the long-term safety of eptinezumab, a medicine used to prevent migraines. It involved 160 Japanese patients who had already completed a previous study. The goal was to see if the drug remained safe and tolerable over an extended period of up to 60 weeks.

This study tested a drug called rimegepant to see if it could prevent migraines in Japanese adults. About 496 people took either the drug or a placebo for 12 weeks. The main goal was to see if the drug reduced the number of migraine days per month. Results showed a decrease in mi…

This study looked at the safety of taking rimegepant every day to prevent episodic migraines. 441 adults with a history of migraines took the daily pill, and researchers tracked side effects. The goal was to see how well people tolerated long-term daily use of this medication.

This study tested a drug called fremanezumab, given as a shot under the skin once a month or once every three months, to prevent migraines in 365 Chinese adults. The main goal was to see if it reduced the number of migraine days per month compared to a placebo. The drug is design…

This study looked at the long-term safety of a monthly injection called fremanezumab to prevent migraine in children aged 6 to 17. Over 500 participants were followed for up to 7 years. The goal was to see if the drug is safe and helps reduce headache days over time.

This study tested a home-based biofeedback app called Cerebri for preventing migraine attacks in adults with episodic migraine. 279 participants either used the app for 10 minutes daily or joined a wait-list group. Researchers compared how much migraine days decreased in each gro…

This study tested whether a tablet called rimegepant can help prevent migraines in Chinese adults aged 18 and older with at least a one-year history of migraines. About 787 participants took either rimegepant or a placebo every other day for 12 weeks, with some continuing for ano…

This study tested a new drug called AXS-07 (a mix of meloxicam and rizatriptan) for treating migraine attacks in adults who had already tried an oral CGRP inhibitor without success. About 100 people took part in this open-label Phase 3 trial. The goal was to see if the drug could…

This study tested three types of medication—blood thinners, anti-clotting drugs, and standard migraine meds—to see which works best for reducing migraine attacks in people who also have a small hole in the heart (PFO). About 1000 adults with frequent migraines took part. The goal…

This study tested a monthly injection called erenumab in 557 Asian adults with chronic migraine (15+ headache days per month). Over 12 weeks, researchers measured how much the drug reduced the number of migraine days compared to a placebo. The goal was to see if the shot could sa…

This study tested whether a new under-the-tongue drug called MTX101 can safely relieve migraine headaches in adults. 78 participants took either the drug or a placebo during a migraine attack and recorded their pain levels and any side effects. The goal was to see if MTX101 reduc…

This study followed about 200 adults in Israel who were prescribed ubrogepant or atogepant for migraines. Researchers wanted to see how satisfied people were with these drugs in everyday use. Participants took the medication as their doctor ordered and reported their satisfaction…

This study looked at how well the migraine medication rimegepant works in real-life settings. Researchers followed 120 migraine patients in the Greater Bay Area to measure their satisfaction, quality of life, and daily functioning. The goal was to see if rimegepant helps people m…

This study tested a new drug called BHV-2100 for treating migraines quickly. About 647 people with migraines took either the drug or a placebo. The goal was to see if the drug could stop headache pain and other bothersome symptoms within 2 hours.

This study tested if inhaling isopropyl alcohol (rubbing alcohol) vapor reduces nausea during a migraine attack better than a placebo scent (eucalyptus). 21 adults with frequent migraines took part. Researchers measured changes in nausea severity and any side effects.

This study tested a biofeedback device that uses muscle signals to help people relax and retrain muscles. It included 330 adults with chronic low back pain, recent breast surgery pain, or migraines. Half used the device plus usual care; the other half had usual care alone. The go…

This study tested whether injecting a small amount of lidocaine (a numbing medicine) into a specific acupoint on the back of the head could safely reduce migraine attacks. Thirty adults with migraines received either weekly lidocaine injections for four weeks or a daily propranol…

This study looked at whether giving children with migraine just intravenous (IV) fluids in the emergency department can ease their headache pain. 46 children took part. Researchers measured pain, nausea, and whether more medicine was needed later. The goal was to see if hydration…

This study tested whether foot reflexology, a type of focused foot massage, could help people with migraines feel less pain and fatigue and have a better quality of life. 78 adults with migraines took part. One group received 10 sessions of foot reflexology over 5 weeks, while th…

This study tested a device that cools the inside of the nose to treat migraine headaches at home. 156 adults with migraines used either the real device or a fake one. The goal was to see if the device could stop pain and other bothersome symptoms within 2 hours.

This study tested if an AI-powered voice chatbot could help Hong Kong women with migraines track their symptoms more accurately and consistently than a traditional paper diary. 49 women used both methods for one month each. The goal was to see if the chatbot improved data complet…

This study tested whether the drug erenumab can prevent migraines in children aged 6 to 17 with chronic migraine (15+ headache days per month). About 284 participants received either the drug or a placebo for 3 months. The main goal was to see if the drug reduced the number of mo…

This study looked at whether combining posture correction with a gentle neck therapy called sustained natural apophyseal glides can reduce migraine pain and disability. 44 adults with episodic migraines took part. Researchers measured pain levels, quality of life, and how much mi…

This study tested a wearable device that uses gentle electrical pulses to treat migraines in US veterans. 466 veterans used the device at home and reported whether they still needed rescue medication after treatment. The goal was to see if the device could effectively ease migrai…

This study tested a new oral medicine, AXS-07, for quickly stopping migraine headaches in adults. 302 people took either the study drug or a placebo pill at the start of a migraine. The main goals were to see if the drug could make headache pain go away within 2 hours and also re…

This study tested a wearable device called Nerivio that uses gentle electrical signals to relieve migraine pain in children ages 6 to 11. About 293 kids who already used the device took part. The goal was to see if it is safe and helps reduce headache pain within two hours.

This study looked at how well and how safely lasmiditan works for treating migraines as they happen. Researchers followed 100 people with migraine (with or without aura) who took the drug during an attack. The main goal was to see if they were pain-free after 2 hours and to track…

This early-stage study looked at whether a new drug called Lu AG09222 is safe to take together with the migraine medication ubrogepant. 43 people with migraine received ubrogepant pills plus an injection of either Lu AG09222 or a placebo. The main goal was to check for any side e…

This study tested a new wearable device that uses gentle electrical pulses on the head and neck to relieve migraine pain. 160 adults with migraines used the device during attacks, and researchers compared real stimulation to a sham (inactive) version. The goal was to see if the d…

This study looked at whether adding progressive muscle relaxation training to aerobic exercise helps people with migraine feel better. 44 adults with migraine were split into two groups: one did both relaxation and exercise, the other did exercise only. Researchers measured pain,…

This study tested a 12-week telehealth program for people with migraine. Twenty participants used a mobile app headache diary, an online manual, and had virtual sessions with a coach. The goal was to see if the program was easy to use and if it helped improve quality of life.

This study looked at whether prayer can change how people with migraines feel pain, anxiety, and depression. About 100 adults, half with migraines and half without, took part. They compared praying to reading a text to see if prayer raised pain tolerance and improved mood.

This study looked at how a nerve stimulation device (like a gentle zap on the neck) combined with stress-reduction training affects the brains of people with migraine. Researchers compared brain scans and inflammation levels in 193 adults with migraine and healthy volunteers. The…

This study looked at how well the migraine medication Rimegepant works in real-world settings. 173 adults with migraine took the drug as needed for attacks or prevention. Researchers tracked pain relief at various times and monitored safety over the long term.

This study tested a drug called rimegepant for quickly treating migraine headaches in adults who cannot use triptans (common migraine drugs) due to side effects, lack of effectiveness, or heart risks. Over 800 participants took either rimegepant or a placebo and reported their pa…

This study checked if using the Nerivio device for migraine headaches during pregnancy and up to 3 months after birth is safe. It compared 145 women with migraine who used Nerivio to those who did not, looking at baby's birth weight, delivery timing, and miscarriage rates. The go…

This study tested the drug erenumab in 512 adults with high-frequency episodic migraine (7 to 14 migraine days per month) who had already tried at least one other preventive treatment without success. The main goal was to see if erenumab could reduce the total hours of moderate-t…

This study tested a type of mindfulness training called Acceptance and Commitment Therapy (ACT) for women who have migraines 4 to 14 days per month. Researchers wanted to see if it's possible to run a larger study and whether ACT can reduce how often migraines happen and how much…

This study examined 45 children with migraine to learn about symptoms they experience after the headache ends, known as the postdrome phase. Researchers asked about symptoms like tiredness or trouble concentrating and looked at how these differ by age and gender. The goal was to …

This early-stage study tested a single inhaled dose of prochlorperazine (a drug used for migraines) in 54 healthy adults aged 18 to 45. The goal was to see if it was safe and tolerable, and to measure how the body absorbs and processes the drug. No treatment benefit was measured;…

This study looked at how people with migraine feel about two types of acute medications: rimegepant and triptans. Researchers used data from a large national health survey in the US, focusing on over 1,300 adults who reported a migraine diagnosis. They compared treatment satisfac…

This study aimed to develop a computer model that can predict whether a person will have a migraine the next day. Researchers used information from over 53,000 people who reported their migraine symptoms and location through the Nerivio app. The goal was to see how accurately the…

This study compared neck stability, neck position sense, and body awareness in 64 adults with migraine (during headache-free periods) and healthy volunteers. Researchers used special tests and questionnaires to measure differences. The goal was to better understand how migraine m…

This observational study followed 210 adults with migraine or tension headaches for 6 months. Participants kept a diary of their headaches and any sensitivity to smells (osmophobia). The goal was to see if smell sensitivity is a reliable sign of migraine versus tension headache. …

This study looked at nearly 2,000 people from the community to understand how depression, anxiety, and migraine are passed down through families. Researchers interviewed family members of all ages to track patterns and risk factors. The goal is to find better ways to prevent and …

This study measured how many infertile women have migraines and how those migraines change during IVF treatment. Researchers followed 137 women aged 18-40 at a fertility center. The goal was to understand the connection between hormone changes from IVF and migraine headaches.

This study looked at what makes it easier or harder for people with migraine and healthcare workers in Thailand to use a new preventive treatment called eptinezumab. Researchers interviewed 30 participants, including patients and providers, and tracked migraine symptoms over 6 mo…

This early-stage study tested a new nasal spray called PRT-064040 in 80 healthy Chinese adults to see if it is safe and how the body processes it. Participants received either a single dose or daily doses for a week. The goal was to gather safety information, not to treat migrain…