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Shock and stretch: new combo therapy for migraine pain?

NCT ID NCT07125820

Symptom relief Sponsor: Suleyman Demirel University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether adding TENS (a device that sends mild electrical pulses through the skin) and exercise to usual migraine medication can reduce pain and disability in women with migraine. Thirty-eight women participated, all continuing their prescribed meds. The goal was to see if these add-ons improve pain, muscle strength, sleep, balance, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcutaneous electrical nerve stimulation (TENS) device and exercise training
What this could lead to
If it works, this could offer a drug-free way to ease migraine pain and improve daily function for women.
What could go wrong
This is a small, completed trial with only 38 participants, so results may not apply to everyone. The effects may be modest and need confirmation in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

38 people

The number who actually took part.

Started

Feb 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Sedentary female individuals aged 18-55 years * Being diagnosed with migraine according to the International Headache Society (IHS) criteria * Having at least 2 migraine attacks per month * Having started the use of medical medication for migraine treatment 3 months or earlier * Not taking medication continuously except for migraine attacks Exclusion Criteria: * Having vestibular migraine * Having another type of concomitant headache * Becoming pregnant * Being breastfeeding * History of trauma or surgery in the craniocervical region * Presence of concomitant neurological (multiple sclerosis, Parkinson's disease, etc.) and/or inflammatory rheumatic diseases (ankylosing spondylitis, rheumatoid arthritis, etc.) * Presence of psychiatric problems (schizophrenia, bipolar disorder, etc.) * History of malignancy * Physiotherapy and rehabilitation for migraine or cervical region in the last 6 months * Botox / filler application to the face area * Not attending research sessions regularly or missing 3 consecutive sessions

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Conditions

The condition(s) this trial relates to.

migraine disorder Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Migraine

Contacts and locations

Locations

  • Baskent University

    Ankara, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.