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Migraine showdown: which drug cuts headaches best?

NCT ID NCT06347497

First seen May 31, 2026 · Last updated Jun 13, 2026 · Updated 3 times

Summary

This study tested two drugs, zonisamide and topiramate, to see which works better for preventing migraines. About 600 people with migraines took one of the medicines for three months. Researchers measured how much their monthly migraine days dropped and how many people had at least half fewer headache days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Kafr Elsheikh University Hospital

    Kafr ash Shaykh, 33511, Egypt

Conditions

The condition(s) this trial relates to.

Migraine Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.