Acupuncture needle with lidocaine may ease migraines
NCT ID NCT07067853
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether injecting lidocaine into the GB20 acupoint (at the back of the neck) can reduce migraine attacks. Thirty adults with migraines received either weekly lidocaine injections for four weeks or daily propranolol pills. Researchers tracked headache frequency, duration, pain intensity, and disability over two months to see if the injections work as well as standard medication.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lidocaine 2% injection at GB20 acupoint
- What this could lead to
- If it works, this could offer a safe, non-oral alternative for migraine relief with fewer daily pills.
- What could go wrong
- This is a small, completed trial with only 30 participants, so results may not apply widely. Lidocaine injections can cause pain, infection, or skin irritation at the injection site.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
30 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 59 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with migraine * Minimum of 3 days of migraine attacks in 1 month * Willing to participate until the study concludes Exclusion Criteria: * Headache with other known cause (e.g. head trauma, cancer, hemorrhagic stroke) * Inaccessible GB20 acupuncture point (scar tissue, infection, open wound, etc) * History of heart disease and/or asthma * History of Hypersensitivity with propranolol and/or lidocaine * History of acupuncture treatment 3 month prior to study * Routine consumption of anticoagulation medications, steroids or pain killers * Pregnant and breastfeeding women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Universitas Indonesia
Jakarta Pusat, DKI Jakarta, 10430, Indonesia
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Other studies related to the condition(s) this trial covers.
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