HEALTHY VOLUNTEERS

This study will monitor the safety of the MenQuadfi vaccine in 706 people aged 6 weeks to 55 years in South Korea. Researchers will track side effects like injection-site reactions and serious adverse events as the vaccine is used in real-world clinics. The goal is to confirm the…

This study is checking the safety of a high-dose flu vaccine called Efluelda in adults aged 65 and older in South Korea. About 670 participants will receive one shot and be monitored for side effects for about a month. The goal is to see how often reactions like injection site pa…

This first-in-human study will test a new radioactive imaging agent called MeFAMP to see if it can safely and accurately detect brain tumors using PET scans. The study includes 28 people: healthy volunteers and patients with recurrent high-grade glioma or brain metastases from ot…

This study tests whether the drug Qsymia, combined with lifestyle coaching, can prevent obesity in 140 adolescents and young adults (ages 18-25) who are overweight (BMI 25-30) and have a family history of obesity. Participants will receive either Qsymia or a placebo, plus coachin…

This study tests whether a single dose of (2R,6R)-HNK, a drug related to ketamine, can reduce short-term pain in healthy adults aged 18-60. Participants will receive either the drug or a placebo and undergo pain tests, blood draws, and brain scans. The goal is to find a safer, no…

This early-stage study will give 24 healthy adults a single dose of Hezkue oral sildenafil suspension after they drink a moderate amount of alcohol. Researchers will measure how the drug enters the blood and how quickly it works. The goal is to understand any changes caused by al…

This early-phase trial will test the safety and tolerability of KMY tablets in 120 healthy adults aged 18 to 45. Participants will receive either the drug or a placebo, and researchers will monitor for side effects and how the drug moves through the body. The study also looks at …

This study will test a new markerless motion capture system that uses only four cameras to analyze how children walk. Researchers will enroll 125 healthy children aged 6 to 17. The goal is to see if this simpler setup can provide useful information about walking patterns, which c…

This early-stage study tests a new drug called CDR132L in 32 healthy adults. Researchers want to see how much of the drug gets into the blood when given as a shot under the skin compared to an IV drip. The goal is to find the best way to give this medicine to people with heart fa…

This study compares 69 healthy volunteers to people with idiopathic environmental intolerance (IEI), a condition where patients experience symptoms like pain or fatigue but no physical cause is found. Researchers will test whether certain thinking patterns or biases make people m…

This study tests a new tool called SOMA, a library of audio exercises designed to make mindfulness research more reliable and inclusive. Researchers want to see if these exercises can separate the effects of mindfulness from just expecting to feel better. The study involves 360 h…

This early-stage study tests the safety and tolerability of a new oral drug called ISM4808 in 86 healthy adults aged 18-55 in China. Participants receive either the drug or a placebo, and researchers monitor for side effects and how the drug moves through the body. The goal is to…

This study looks at how a new tablet form of the drug sonrotoclax (dissolved in liquid) is absorbed into the body compared to the current tablet. It also checks if eating food changes how much of the drug gets into the blood. The study involves 12 healthy adults and is not yet re…

This study checks if two drugs, IN-M00007 and IN-R00007, are bioequivalent—meaning they work the same in the body. About 60 healthy adults aged 19 to 59 will take a single dose of each drug at different times. The main goal is to measure how the drugs are absorbed and to ensure t…

This study looks at how different durations (5, 10, and 15 minutes) of a gentle ear nerve stimulation affect heart rate, blood pressure, and breathing in healthy adults aged 18 to 40. Participants will receive either real or fake (sham) stimulation on separate visits. The goal is…

This study looks at how different phases of the menstrual cycle relate to muscle strength and physical performance in healthy, active women aged 18 to 35. Participants will track their cycle with a phone app and attend three lab visits for strength tests and body measurements. Th…

This study looks at how a targeted nerve block near the wrist changes blood flow in the fingers and hands of 20 healthy adults. Researchers will use sensors and thermal cameras to measure these changes before and after the block. The goal is to better understand how the nervous s…

This study tests whether doing sit-to-stand exercises with a blood flow restriction cuff on the thigh can improve back muscle endurance and balance more than the same exercises without the cuff. Seventy healthy young adults aged 20-25 will be randomly assigned to one of two group…

This study looks at whether Kinesio Taping can immediately improve hand and arm function in healthy adults. 36 volunteers will be randomly assigned to receive real Kinesio Tape, sham tape (no tension), or no tape at all. They will then perform tests like grip strength, typing, an…

This early-stage study looks at how a high-fat meal or a standard meal changes the way the body absorbs a single dose of the drug VV913. Twelve healthy Chinese men will take the drug under different meal conditions to measure side effects and drug levels in the blood. The results…

This study explores how focused ultrasound can change brain activity in healthy adults. Researchers will send sound waves through the skull to the visual and hearing parts of the brain to see what people perceive. The goal is to find the best settings for future treatments of con…

This early-stage study tests whether a new formulation of the antibiotic polymyxin B (VRP-034) is safer for the kidneys than the current version. It involves 48 healthy adult men who will receive one or more doses of either the new or standard drug. Researchers will measure kidne…

This study aims to see if liquid metformin causes fewer stomach problems than the standard tablet form. Twenty-four healthy adults will try both liquid versions and tablets, and researchers will track any side effects. The goal is to find a more tolerable option for people who ne…

This early-stage study will test a new version of the drug dupilumab in 40 healthy adults aged 18 to 60. The new version includes an enzyme that may help the drug spread better under the skin. Researchers will measure how the drug moves through the body and check for side effects…

This study looks at whether an 8-week dairy drink with extra protein, calcium, and vitamin D can help physically active adults aged 18-39. About 50 volunteers will drink the product and take tests on strength, body composition, and how they feel. The goal is to see if the drink i…

This early-stage study will test how two different liquid forms of metformin affect blood sugar compared to regular metformin tablets. Twenty-four healthy adults will take short-term doses and have their blood glucose measured. The goal is to see if the liquid versions work diffe…

This study looks at how brief periods of low oxygen (intermittent hypoxia) affect a measure called 'loop gain,' which reflects how your body controls breathing. Researchers want to understand if these oxygen dips can make breathing control less stable, which may help explain slee…

This study looks at how the body handles the experimental drug BGB-58067 when taken with two common medicines that change liver enzyme activity. Thirty healthy adults will take BGB-58067 with either phenytoin (an enzyme booster) or itraconazole (an enzyme blocker). The goal is to…

This study looks at how the design of breathing masks affects breathing in 10 healthy volunteers. Participants will try four different masks while using a breathing machine. The goal is to see if mask design changes breathing patterns, carbon dioxide levels, and breathing rate. T…

This early-stage study tests the safety and tolerability of a new drug called migaldendranib in 36 healthy volunteers. Participants receive weekly injections, and researchers monitor for side effects and how the drug moves through the body. The study does not aim to treat any dis…

This early-stage study tests a new drug called BMS-986533 in 118 healthy adults to see if it's safe and how the body processes it. Researchers will also check if food or stomach acid changes how the drug works, and if it interacts with other medications. Participants will not rec…

This early-stage trial tests the safety and how the body processes VV913 capsules in 24 healthy Chinese men aged 18-45. Participants receive multiple doses to check for side effects and measure drug levels in the blood. The study is not intended to treat any disease but to gather…

This study tests whether a supplement called TRPTI (oleoylethanolamide) can improve gut health and metabolism in healthy adults. Researchers will measure changes in blood markers and gut bacteria over 8 weeks. 90 healthy adults aged 18+ with a BMI between 18.5 and 29.9 will take …

This study looks at how two types of fasting—Ramadan dry fasting (no food or water from dawn to sunset) and standard 16:8 time-restricted feeding (water allowed)—affect the body's ability to clean out and renew mitochondria, the energy centers of cells. Researchers will measure b…

This study looks at how stimulating a nerve in the ear with different frequencies changes heart rate, blood pressure, and breathing in healthy adults aged 18 to 40. Each person will try five different stimulation settings (including a sham) in separate sessions. The goal is to un…

This study looks at whether the hormone progesterone changes how muscles build protein after resistance exercise. Twenty healthy women aged 18-30 will take either progesterone pills or a placebo, then do leg exercises. Researchers will measure muscle growth using biopsies and blo…

This study explores whether real-time brain scans (fMRI) can help healthy people change how they perceive social situations. Ten volunteers will undergo six MRI sessions while watching animations and receiving feedback on their brain activity. The goal is to understand the brain'…

This early-stage study tests a new type of brain stimulation called high-density theta burst stimulation (hdTBS) in 35 healthy adults aged 22 to 60. The goal is to check if it is safe and to see how it affects the brain compared to standard stimulation. Participants will have fou…

This early-stage study tests the safety of a new drug called HS-20152 in 32 healthy adults aged 18 to 64. The drug targets the complement system, part of the body's immune response. Researchers will monitor for side effects and measure how the drug moves through the body. This st…

This early-stage study looks at how food and ethnic background affect the way a new drug, JPI-547, moves through the body. It involves 36 healthy men of Korean, Caucasian, or Chinese descent who take a single dose. The goal is to gather safety and drug-level data, not to treat an…

This study looks at how stimulating the vagus nerve at different frequencies changes heart rate, blood pressure, and breathing in healthy adults aged 18-30. Each person will try five different stimulation settings (including a sham/placebo) in random order. The goal is to find wh…

This study tests a new computer method (HDC) to recognize hand gestures using muscle sensors on the forearm. Ten healthy volunteers will perform gestures while wearing a sensor armband. The goal is to see if the new method is more accurate than standard approaches. This is a tech…

This study looks at how long heart rate recordings should be to best detect changes from a mild nerve stimulation in the ear. Forty healthy adults will receive both real and fake stimulation in random order. Researchers will compare 1-minute, 5-minute, and 10-minute recordings to…

This study looks at whether a single dose of nicotinamide riboside (NR), a common supplement, can change sleep patterns in healthy adults who have mild sleep troubles. Twenty volunteers will have their sleep measured overnight with advanced monitoring after taking either NR or a …

This study looks at how different vibration frequencies from a smartphone app affect hand performance in healthy young adults. Twenty participants will test three vibration levels on their dominant hand, measuring grip strength, touch sensitivity, pain threshold, and reaction tim…