HEALTHY VOLUNTEERS

This study tests whether a single dose of an experimental drug called (2R,6R)-HNK can safely reduce short-term pain in healthy adults. HNK is related to ketamine but may have fewer side effects. Researchers will compare HNK to a placebo in 92 volunteers using pain tests and brain…

This study follows 100 healthy adults aged 18 to 29 who already carry the Epstein-Barr virus. Researchers collect blood and saliva samples over 6 to 12 months to learn when and why the virus becomes active again. No treatments or vaccines are given—the goal is simply to gather da…

This study looks at how long heart rate recordings should be to accurately measure the body's response to a mild nerve stimulation in the ear. Forty healthy adults will receive both real and fake stimulation in random order. Researchers will compare 1-minute, 5-minute, and 10-min…

This early-stage study tests a single dose of the experimental drug VV913 in 56 healthy Chinese men aged 18 to 45. The goal is to check safety, side effects, and how the drug moves through the body. No treatment for any disease is being tested here.

This early-stage study tests the safety and tolerability of KMY tablets in 120 healthy adults aged 18-45. Participants receive single or multiple doses, and some take the tablet with a high-fat meal to see how food affects the drug. The goal is to gather safety data and understan…

This study compares 69 people with idiopathic environmental intolerance (IEI) — who experience symptoms like pain, fatigue, or dizziness from everyday exposures — to healthy volunteers. Researchers will test whether certain thinking patterns (cognitive biases) make the brain over…

This study looks at how a gentle, non-invasive nerve stimulation on the ear affects heart rate, blood pressure, and breathing in healthy adults aged 18 to 40. Participants will receive either real or fake stimulation for 5, 10, or 15 minutes on separate visits. The goal is to see…

This study tests whether liquid metformin causes fewer stomach side effects than standard tablets. Twenty-four healthy adults will try both forms and report any discomfort. The goal is to find a better-tolerated option for people who need metformin.

This study checks if two versions of a drug (IN-M00007 and IN-R00007) are absorbed and processed the same way in the body. Sixty healthy adults aged 19 to 59 will take a single dose of each drug at different times. The goal is to see if they are bioequivalent, meaning they can be…

This study tests whether real-time brain imaging (fMRI) can help healthy volunteers change how they perceive social situations, like seeing interactions as positive or negative. Ten participants will undergo six MRI sessions while receiving feedback on their brain activity. The g…

This study looks at whether the design of a breathing mask affects how healthy people breathe while using non-invasive ventilation (NIV). Ten healthy adults will try four different masks and have their breathing measured. The goal is to learn which mask designs work best, which c…

This study looks at how brief periods of low oxygen (intermittent hypoxia) change the body's breathing control system in 40 healthy adults aged 18-45. Participants will spend time in a special chamber, and researchers will measure breathing stability before and after. The goal is…

This study looks at whether a single dose of nicotinamide riboside (NR), a common supplement, can change how healthy adults sleep. Twenty people with mild sleep troubles will have their sleep measured in a lab after taking either NR or a placebo. The goal is to see if NR has any …

This early-stage study tests the safety and tolerability of a new drug called migaldendranib in 36 healthy volunteers. Participants receive multiple doses, and researchers monitor side effects and how the drug moves through the body. The goal is to gather safety information, not …

This study tests a new computer algorithm to better recognize hand gestures from muscle signals. Ten healthy adults will wear a sensor armband and perform hand movements. The goal is to see if the new method is more accurate than existing techniques. This is a technology test, no…

This study tests three different breath-activated inhaler devices in 10 healthy adults. Each person tries all three devices in random order. The goal is to see how well they measure airflow, record breaths, and feel comfortable to use. No medication is involved—only an inactive s…

This study aims to create and test a Turkish version of a questionnaire that measures cybersickness—symptoms like nausea and eye strain—experienced during virtual reality use. Researchers will enroll 42 healthy adults who can stand and walk independently. The goal is to ensure th…

This early-stage study tests a new drug called ZE74-0282 in 40 healthy adults aged 18 to 55. The main goal is to check its safety and how the body handles it, not to treat any disease. Participants receive either the drug or a placebo, and researchers monitor side effects and dru…

This study looks at how different frequencies of a mild ear nerve stimulation (taVNS) change heart rate, blood pressure, and breathing in healthy adults aged 18 to 40. Each person will try five different stimulation settings (including a sham) in separate sessions. The goal is to…

This study will test a new, simpler motion capture system that uses only four cameras to analyze how children walk. Current systems require special labs and many cameras, limiting their use. The goal is to see if this easier method can be used for routine check-ups in children wi…

This early-stage study will test the safety and tolerability of a single dose of HS-20152, a new drug that targets the complement pathway (part of the immune system), in 32 healthy adults aged 18 to 64. Participants will be randomly assigned to receive either the drug or a placeb…

This study looks at how different phases of the menstrual cycle relate to muscle strength and physical performance in healthy, active women aged 18 to 35. Participants will track their cycle with a phone app for about two months and attend three lab visits for strength tests and …

This study looks at how a targeted nerve block near the wrist affects blood flow and hand temperature in 20 healthy adults. Participants will receive an ultrasound-guided injection of anesthetic around the radial artery, and researchers will measure changes in finger pulse and ha…

This study checks if a new drug called IBI3027 works the same as the approved drug Dupilumab in healthy Chinese men aged 18-45. Participants get one injection and are monitored for 56 days. The goal is to compare drug levels and safety, not to treat any disease.

This early-stage study tests a new oral drug called ISM4808 in 86 healthy adults in China. The main goal is to check if the drug is safe and how the body processes it. Participants will receive either the drug or a placebo, and researchers will monitor for side effects. This stud…

This early-stage study looks at how a new drug called CS0159 behaves in the body when taken with a high-fat meal or with other common medications (rifampicin and itraconazole). The goal is to understand how these factors affect drug levels and safety. Thirty-two healthy adults ag…

This early-stage study tests how two different liquid forms of metformin affect blood sugar compared to regular metformin tablets. Twenty-four healthy adults will take single or short-term doses of each version in a random order. Researchers will measure blood sugar levels and ch…