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Healthy volunteers to unlock secrets of sleep apnea in new hypoxia study

NCT ID NCT07409649

Knowledge-focused Sponsor: Poitiers University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how brief periods of low oxygen (intermittent hypoxia) affect a measure called 'loop gain,' which reflects how your body controls breathing. Researchers want to understand if these oxygen dips can make breathing control less stable, which may help explain sleep apnea. Forty healthy adults aged 18-45 will spend 6 hours in a special chamber, either breathing normal air or air with low oxygen, while their breathing is measured.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy subjects aged 18 to 45 * BMI between \[18-25\] kg/m2 * No known sleep disorders * Free subjects, not under guardianship or curatorship or subordination * Persons affiliated with or beneficiaries of a Social Security scheme * Signature of informed consent after clear and honest information about the study Exclusion Criteria: * Active smoking or cessation within the last 3 months and total consumption \> 10 pack-years * Alcohol or drug addiction * Excessive coffee consumption (\> 3 espressos/day) * History of acute mountain sickness (presence of symptoms such as dizziness, headaches, nausea/vomiting, and incapacitating fatigue during or after a stay at high altitude) * Living at high altitude (above 3,000 meters, continuously for more than 6 months during the last 10 years) * History of respiratory and/or cardiovascular and/or renal and/or neurological disease (migraines, epilepsy) * Diabetes * Anemia, sickle cell anemia * Any medication associated with oxygen metabolism and any psychotropic medication (anxiolytics, sedatives, antidepressants, neuroleptics, muscle relaxants, etc.) that may interfere with motor and respiratory control, muscle strength, or sleep quality * Women of childbearing age who do not use effective contraception (hormonal/mechanical: oral, injectable, transcutaneous, implantable, intrauterine device, or surgical: tubal ligation, hysterectomy, total ovariectomy) * Concurrent participation in another clinical research study affecting respiratory control or respiratory muscles * Persons benefiting from enhanced protection, namely minors, persons deprived of their liberty by judicial or administrative decision, persons staying in a healthcare facility

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers Intermittent hypoxia

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Poitiers University Hospital

    Poitiers, 86000, France

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