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Why do some people feel sick from everyday things? new study looks at the Brain's role

NCT ID NCT06800976

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study will compare 69 healthy volunteers to people with idiopathic environmental intolerance (IEI), a condition where patients experience symptoms like pain, fatigue, or dizziness from everyday exposures (e.g., chemicals, Wi-Fi) with no clear medical cause. Researchers will test whether differences in how the brain processes beliefs versus body signals explain these symptoms. The goal is to better understand IEI and eventually improve diagnosis and treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help explain why some people develop physical symptoms from environmental triggers without a clear medical cause, pointing toward better diagnostic tools and treatments.
What could go wrong
This is a small, early-stage observational study (69 participants) that only compares groups, not tests a treatment. Results may not apply to all IEI patients or lead directly to therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

69 people

The number who actually took part.

Started

Feb 2025

Finished

Jun 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

We are recruiting healthy participants that will be age- and gender-matched to participants in the BELIEFS study, who live with idiopathic environmental intolerances.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years of age or older; not suffering from an idiopathic environmental intolerance; informed consent is given. Exclusion Criteria: * Suffering from a current psychiatric or neurological condition * not being fluent in spoken and written French * person subject to a period of exclusion for other research * being imprisoned/jailed * being hospitalized * Persons of legal age who are subject to a legal protection measure (e.g. conservatorship, guardianship), persons of legal age who are unable to express their consent and who are not subject to a protection measure. * being pregnant or breast-feeding Translated with DeepL.com (free version)

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Conditions

The condition(s) this trial relates to.

Multiple Chemical Sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers Idiopathic environmental intolerance

Contacts and locations

Locations

  • Unité de pathologies professionnelles et environnementales, Hôtel-Dieu

    Paris, Île-de-France Region, 75004, France

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