Why do some people feel sick from everyday things? new study looks at the Brain's role

NCT ID NCT06800976

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study will compare 69 healthy volunteers to people with idiopathic environmental intolerance (IEI), a condition where patients experience symptoms like pain, fatigue, or dizziness from everyday exposures (e.g., chemicals, Wi-Fi) with no clear medical cause. Researchers will test whether differences in how the brain processes beliefs versus body signals explain these symptoms. The goal is to better understand IEI and eventually improve diagnosis and treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help explain why some people develop physical symptoms from environmental triggers without a clear medical cause, pointing toward better diagnostic tools and treatments.
What could go wrong: This is a small, early-stage observational study (69 participants) that only compares groups, not tests a treatment. Results may not apply to all IEI patients or lead directly to therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Multiple Chemical Sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY VOLUNTEERS IDIOPATHIC ENVIRONMENTAL INTOLERANCE

Contacts and locations

Locations

Unité de pathologies professionnelles et environnementales, Hôtel-Dieu

Paris, Île-de-France Region, 75004, France

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